Project measure / variable:   Wiltshire4   Bcells_BEZ_D

ID, description, units MPD:52405   Bcells_BEZ_D   B cells, percent viability   [%]  dose: 11.1 µM  
BEZ235 study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - B cells, percent viability dose: 11.1 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means90.0   %
Median of the strain means85.6   %
SD of the strain means± 21.4
Coefficient of variation (CV)0.238
Min–max range of strain means58.7   –   167   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 57761.6081 1750.3518 3.2011 < 0.0001
Residuals 99 54132.1192 546.7891


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 113.0 11.6   4 5.82 0.103 99.4, 125.0 1.08
129X1/SvJ m 84.7 9.8   4 4.9 0.116 75.3, 97.3 -0.25
A/J m 90.1 9.5   4 4.75 0.105 79.3, 101.0 0.01
AKR/J m 99.9 0.928   4 0.464 0.00929 98.5, 100.0 0.46
BALB/cByJ m 100.0 4.04   4 2.02 0.0404 94.2, 103.0 0.47
BTBR T+ Itpr3tf/J m 80.6 16.3   4 8.17 0.203 67.0, 103.0 -0.44
BUB/BnJ m 79.1 20.8   4 10.4 0.263 58.5, 107.0 -0.51
C3H/HeJ m 71.4 16.7   4 8.37 0.235 56.9, 88.7 -0.87
C57BL/6J m 89.7 13.3   4 6.65 0.148 71.9, 100.0 -0.01
C57BLKS/J m 99.0 30.3   4 15.1 0.306 69.7, 141.0 0.42
C58/J m 62.2 13.4   2   9.45 0.215 52.7, 71.6 -1.3
CBA/J m 167.0 39.9   4 19.9 0.239 130.0, 223.0 3.6
CZECHII/EiJ m 83.8 17.7   4 8.86 0.211 58.9, 96.9 -0.29
DBA/2J m 96.5 33.1   4 16.5 0.343 47.6, 121.0 0.3
FVB/NJ m 103.0 11.1   4 5.57 0.108 87.2, 113.0 0.61
I/LnJ m 84.0 16.0   4 7.98 0.19 68.7, 104.0 -0.28
KK/HlJ m 80.8 12.7   4 6.35 0.157 72.7, 99.8 -0.43
LG/J m 99.5 20.3   4 10.2 0.204 86.1, 129.0 0.44
LP/J m 73.8 22.9   4 11.4 0.31 58.7, 108.0 -0.76
MA/MyJ m 84.7 13.4   4 6.68 0.158 69.7, 101.0 -0.25
NOD/ShiLtJ m 71.3 26.4   4 13.2 0.371 51.2, 109.0 -0.87
NON/ShiLtJ m 88.7 9.75   4 4.87 0.11 75.8, 97.1 -0.06
NZB/BlNJ m 97.0 4.03   4 2.02 0.0416 91.0, 99.2 0.33
NZO/HlLtJ m 74.2 25.0   4 12.5 0.337 51.4, 107.0 -0.74
NZW/LacJ m 58.7 25.2   4 12.6 0.429 43.4, 96.2 -1.46
PERA/EiJ m 92.4 33.5   4 16.7 0.362 53.7, 122.0 0.11
PL/J m 80.3 28.7   4 14.3 0.357 45.8, 114.0 -0.45
PWD/PhJ m 139.0 68.1   4 34.1 0.492 81.6, 236.0 2.29
PWK/PhJ m 86.5 20.2   4 10.1 0.233 57.2, 103.0 -0.16
RIIIS/J m 96.5 4.47   4 2.24 0.0464 92.5, 103.0 0.3
SEA/GnJ m 75.2 12.5   4 6.24 0.166 62.6, 91.3 -0.69
SJL/J m 77.3 32.8   4 16.4 0.425 48.9, 123.0 -0.59
SM/J m 60.6 23.5   4 11.8 0.388 42.1, 91.8 -1.37
WSB/EiJ m 119.0 8.27   3 4.77 0.0697 111.0, 128.0 1.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 112.66 11.6918 135.859 89.461
129X1/SvJ m 84.68 11.6918 107.879 61.481
A/J m 90.1175 11.6918 113.3165 66.9185
AKR/J m 99.9 11.6918 123.099 76.701
BALB/cByJ m 100.1375 11.6918 123.3365 76.9385
BTBR T+ Itpr3tf/J m 80.62 11.6918 103.819 57.421
BUB/BnJ m 79.1075 11.6918 102.3065 55.9085
C3H/HeJ m 71.3925 11.6918 94.5915 48.1935
C57BL/6J m 89.74 11.6918 112.939 66.541
C57BLKS/J m 99.0125 11.6918 122.2115 75.8135
C58/J m 62.19 16.5346 94.9983 29.3817
CBA/J m 166.9525 11.6918 190.1515 143.7535
CZECHII/EiJ m 83.85 11.6918 107.049 60.651
DBA/2J m 96.505 11.6918 119.704 73.306
FVB/NJ m 102.935 11.6918 126.134 79.736
I/LnJ m 84.0175 11.6918 107.2165 60.8185
KK/HlJ m 80.8475 11.6918 104.0465 57.6485
LG/J m 99.48 11.6918 122.679 76.281
LP/J m 73.7525 11.6918 96.9515 50.5535
MA/MyJ m 84.715 11.6918 107.914 61.516
NOD/ShiLtJ m 71.2725 11.6918 94.4715 48.0735
NON/ShiLtJ m 88.6775 11.6918 111.8765 65.4785
NZB/BlNJ m 96.9925 11.6918 120.1915 73.7935
NZO/HlLtJ m 74.24 11.6918 97.439 51.041
NZW/LacJ m 58.7 11.6918 81.899 35.501
PERA/EiJ m 92.35 11.6918 115.549 69.151
PL/J m 80.35 11.6918 103.549 57.151
PWD/PhJ m 138.61 11.6918 161.809 115.411
PWK/PhJ m 86.51 11.6918 109.709 63.311
RIIIS/J m 96.515 11.6918 119.714 73.316
SEA/GnJ m 75.2225 11.6918 98.4215 52.0235
SJL/J m 77.295 11.6918 100.494 54.096
SM/J m 60.625 11.6918 83.824 37.426
WSB/EiJ m 118.73 13.5005 145.5179 91.9421




  GWAS USING LINEAR MIXED MODELS