Phenotype measure:   Wiltshire4   monocytes_Sel_A

ID, description, units MPD:52474   monocytes_Sel_A   monocytes, percent viability   [%]  dose: 0.046 µM
selumetinib study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Wiltshire4 - monocytes, percent viability dose: 0.046 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means99.8   %
Median of the strain means100   %
SD of the strain means± 6.58
Coefficient of variation (CV)0.0659
Min–max range of strain means76.5   –   114   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 4559.2939 138.1604 1.1609 0.2822
Residuals 99 11782.4416 119.0146


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 107.0 11.3   4 5.63 0.105 90.3, 114.0 1.1
129X1/SvJ m 99.0 3.76   4 1.88 0.038 94.9, 104.0 -0.12
A/J m 101.0 5.59   4 2.79 0.0551 97.0, 109.0 0.19
AKR/J m 101.0 4.5   4 2.25 0.0445 94.4, 104.0 0.19
BALB/cByJ m 100.0 4.52   4 2.26 0.0451 97.5, 107.0 0.03
BTBR T+ Itpr3tf/J m 96.9 5.15   4 2.58 0.0532 89.5, 102.0 -0.44
BUB/BnJ m 94.9 4.16   4 2.08 0.0438 89.7, 99.8 -0.74
C3H/HeJ m 99.5 1.77   4 0.885 0.0178 97.7, 101.0 -0.04
C57BL/6J m 101.0 1.93   4 0.967 0.0191 98.6, 103.0 0.19
C57BLKS/J m 95.7 15.3   4 7.66 0.16 78.1, 113.0 -0.62
C58/J m 76.5 10.3   2   7.25 0.134 69.2, 83.7 -3.54
CBA/J m 100.0 12.6   4 6.31 0.126 85.5, 112.0 0.03
CZECHII/EiJ m 101.0 8.31   4 4.16 0.0819 92.7, 109.0 0.19
DBA/2J m 90.0 13.2   4 6.58 0.146 79.4, 109.0 -1.49
FVB/NJ m 96.6 3.21   4 1.6 0.0332 93.6, 101.0 -0.48
I/LnJ m 103.0 2.84   4 1.42 0.0275 99.4, 106.0 0.49
KK/HlJ m 90.5 11.9   4 5.97 0.132 75.3, 101.0 -1.41
LG/J m 105.0 6.24   4 3.12 0.0597 99.7, 113.0 0.79
LP/J m 103.0 5.2   4 2.6 0.0503 97.8, 110.0 0.49
MA/MyJ m 100.0 1.7   4 0.849 0.017 97.5, 101.0 0.03
NOD/ShiLtJ m 104.0 19.7   4 9.83 0.188 92.4, 134.0 0.64
NON/ShiLtJ m 103.0 12.6   4 6.28 0.122 93.2, 121.0 0.49
NZB/BlNJ m 101.0 3.61   4 1.81 0.0359 95.4, 103.0 0.19
NZO/HlLtJ m 95.6 2.12   4 1.06 0.0222 92.7, 97.8 -0.64
NZW/LacJ m 91.0 10.7   4 5.33 0.117 78.1, 104.0 -1.33
PERA/EiJ m 102.0 12.7   4 6.34 0.125 87.3, 118.0 0.34
PL/J m 103.0 2.01   4 1.0 0.0195 100.0, 105.0 0.49
PWD/PhJ m 99.2 13.4   4 6.68 0.135 81.5, 114.0 -0.09
PWK/PhJ m 102.0 12.5   4 6.24 0.123 85.2, 115.0 0.34
RIIIS/J m 114.0 21.3   4 10.7 0.186 88.0, 139.0 2.16
SEA/GnJ m 98.1 4.24   4 2.12 0.0432 94.8, 104.0 -0.26
SJL/J m 106.0 4.28   4 2.14 0.0402 103.0, 113.0 0.95
SM/J m 100.0 7.43   4 3.71 0.0739 89.3, 105.0 0.03
WSB/EiJ m 112.0 39.5   3 22.8 0.353 73.8, 153.0 1.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 107.0325 5.4547 117.8558 96.2092
129X1/SvJ m 99.04 5.4547 109.8633 88.2167
A/J m 101.4275 5.4547 112.2508 90.6042
AKR/J m 101.13 5.4547 111.9533 90.3067
BALB/cByJ m 100.34 5.4547 111.1633 89.5167
BTBR T+ Itpr3tf/J m 96.9025 5.4547 107.7258 86.0792
BUB/BnJ m 94.9475 5.4547 105.7708 84.1242
C3H/HeJ m 99.51 5.4547 110.3333 88.6867
C57BL/6J m 101.225 5.4547 112.0483 90.4017
C57BLKS/J m 95.7225 5.4547 106.5458 84.8992
C58/J m 76.485 7.7141 91.7914 61.1786
CBA/J m 100.385 5.4547 111.2083 89.5617
CZECHII/EiJ m 101.49 5.4547 112.3133 90.6667
DBA/2J m 89.9975 5.4547 100.8208 79.1742
FVB/NJ m 96.59 5.4547 107.4133 85.7667
I/LnJ m 103.1025 5.4547 113.9258 92.2792
KK/HlJ m 90.545 5.4547 101.3683 79.7217
LG/J m 104.635 5.4547 115.4583 93.8117
LP/J m 103.415 5.4547 114.2383 92.5917
MA/MyJ m 100.025 5.4547 110.8483 89.2017
NOD/ShiLtJ m 104.2975 5.4547 115.1208 93.4742
NON/ShiLtJ m 102.9725 5.4547 113.7958 92.1492
NZB/BlNJ m 100.6 5.4547 111.4233 89.7767
NZO/HlLtJ m 95.5575 5.4547 106.3808 84.7342
NZW/LacJ m 91.03 5.4547 101.8533 80.2067
PERA/EiJ m 101.68 5.4547 112.5033 90.8567
PL/J m 102.9925 5.4547 113.8158 92.1692
PWD/PhJ m 99.2425 5.4547 110.0658 88.4192
PWK/PhJ m 101.825 5.4547 112.6483 91.0017
RIIIS/J m 114.475 5.4547 125.2983 103.6517
SEA/GnJ m 98.1125 5.4547 108.9358 87.2892
SJL/J m 106.4625 5.4547 117.2858 95.6392
SM/J m 100.4525 5.4547 111.2758 89.6292
WSB/EiJ m 112.12 6.2985 124.6177 99.6223




  GWAS USING LINEAR MIXED MODELS