Project measure / variable:   Wiltshire4   monocytes_BEZ_A

ID, description, units MPD:52414   monocytes_BEZ_A   monocytes, percent viability   [%]  dose: 0.046 µM  
BEZ235 study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - monocytes, percent viability dose: 0.046 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means99.4   %
Median of the strain means99.2   %
SD of the strain means± 10.4
Coefficient of variation (CV)0.105
Min–max range of strain means76.2   –   140   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 14129.7096 428.173 1.8976 0.0082
Residuals 99 22338.0321 225.6367


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 140.0 9.53   4 4.76 0.0678 129.0, 152.0 3.88
129X1/SvJ m 101.0 4.51   4 2.25 0.0447 96.4, 106.0 0.15
A/J m 99.1 9.61   4 4.81 0.097 88.5, 109.0 -0.03
AKR/J m 98.8 1.14   4 0.57 0.0115 97.5, 100.0 -0.06
BALB/cByJ m 99.7 9.41   4 4.71 0.0944 87.3, 110.0 0.03
BTBR T+ Itpr3tf/J m 108.0 10.4   4 5.21 0.0965 93.4, 118.0 0.82
BUB/BnJ m 99.3 3.56   4 1.78 0.0358 94.8, 104.0 -0.01
C3H/HeJ m 99.7 2.38   4 1.19 0.0239 97.5, 102.0 0.03
C57BL/6J m 101.0 1.85   4 0.923 0.0183 98.6, 103.0 0.15
C57BLKS/J m 76.2 51.5   4 25.7 0.676 -2.22
C58/J m 96.1 25.5   2   18.0 0.265 78.1, 114.0 -0.32
CBA/J m 99.4 14.6   4 7.31 0.147 83.0, 112.0 0.0
CZECHII/EiJ m 104.0 6.73   4 3.36 0.0644 97.4, 112.0 0.44
DBA/2J m 108.0 23.2   4 11.6 0.215 88.7, 139.0 0.82
FVB/NJ m 97.3 5.95   4 2.97 0.0611 91.4, 105.0 -0.2
I/LnJ m 96.7 5.04   4 2.52 0.0521 89.6, 101.0 -0.26
KK/HlJ m 86.3 7.75   4 3.87 0.0898 77.3, 95.5 -1.26
LG/J m 99.4 7.98   4 3.99 0.0802 93.5, 111.0 0.0
LP/J m 103.0 6.86   4 3.43 0.0664 96.4, 112.0 0.34
MA/MyJ m 100.0 1.2   4 0.602 0.012 98.2, 101.0 0.06
NOD/ShiLtJ m 98.5 8.84   4 4.42 0.0898 88.8, 106.0 -0.09
NON/ShiLtJ m 98.7 13.5   4 6.74 0.137 85.5, 113.0 -0.07
NZB/BlNJ m 98.6 0.935   4 0.467 0.00948 97.6, 99.7 -0.08
NZO/HlLtJ m 98.7 3.27   4 1.63 0.0331 95.5, 102.0 -0.07
NZW/LacJ m 96.2 9.84   4 4.92 0.102 84.0, 108.0 -0.31
PERA/EiJ m 94.4 17.3   4 8.64 0.183 74.3, 116.0 -0.48
PL/J m 101.0 1.28   4 0.638 0.0126 99.1, 102.0 0.15
PWD/PhJ m 93.7 14.0   4 7.02 0.15 80.1, 112.0 -0.55
PWK/PhJ m 94.1 7.47   4 3.73 0.0793 85.1, 100.0 -0.51
RIIIS/J m 78.4 11.5   4 5.75 0.147 62.5, 90.0 -2.01
SEA/GnJ m 102.0 6.06   4 3.03 0.0597 97.3, 110.0 0.25
SJL/J m 91.8 4.2   4 2.1 0.0458 86.7, 95.9 -0.73
SM/J m 101.0 2.46   4 1.23 0.0243 98.8, 104.0 0.15
WSB/EiJ m 120.0 55.0   3 31.7 0.458 71.4, 180.0 1.97


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 140.445 7.5106 155.3477 125.5423
129X1/SvJ m 100.79 7.5106 115.6927 85.8873
A/J m 99.07 7.5106 113.9727 84.1673
AKR/J m 98.8275 7.5106 113.7302 83.9248
BALB/cByJ m 99.745 7.5106 114.6477 84.8423
BTBR T+ Itpr3tf/J m 107.88 7.5106 122.7827 92.9773
BUB/BnJ m 99.3225 7.5106 114.2252 84.4198
C3H/HeJ m 99.695 7.5106 114.5977 84.7923
C57BL/6J m 101.0375 7.5106 115.9402 86.1348
C57BLKS/J m 76.175 7.5106 91.0777 61.2723
C58/J m 96.13 10.6216 117.2056 75.0544
CBA/J m 99.3975 7.5106 114.3002 84.4948
CZECHII/EiJ m 104.4525 7.5106 119.3552 89.5498
DBA/2J m 107.935 7.5106 122.8377 93.0323
FVB/NJ m 97.3325 7.5106 112.2352 82.4298
I/LnJ m 96.66 7.5106 111.5627 81.7573
KK/HlJ m 86.295 7.5106 101.1977 71.3923
LG/J m 99.4325 7.5106 114.3352 84.5298
LP/J m 103.365 7.5106 118.2677 88.4623
MA/MyJ m 99.975 7.5106 114.8777 85.0723
NOD/ShiLtJ m 98.5025 7.5106 113.4052 83.5998
NON/ShiLtJ m 98.6925 7.5106 113.5952 83.7898
NZB/BlNJ m 98.6225 7.5106 113.5252 83.7198
NZO/HlLtJ m 98.7175 7.5106 113.6202 83.8148
NZW/LacJ m 96.1675 7.5106 111.0702 81.2648
PERA/EiJ m 94.3725 7.5106 109.2752 79.4698
PL/J m 100.94 7.5106 115.8427 86.0373
PWD/PhJ m 93.6925 7.5106 108.5952 78.7898
PWK/PhJ m 94.1025 7.5106 109.0052 79.1998
RIIIS/J m 78.44 7.5106 93.3427 63.5373
SEA/GnJ m 101.5225 7.5106 116.4252 86.6198
SJL/J m 91.79 7.5106 106.6927 76.8873
SM/J m 101.3975 7.5106 116.3002 86.4948
WSB/EiJ m 120.0933 8.6725 137.3015 102.8852




  GWAS USING LINEAR MIXED MODELS