Project measure / variable:   Wiltshire4   monocytes_Sel_C

ID, description, units MPD:52476   monocytes_Sel_C   monocytes, percent viability   [%]  dose: 1.235 µM  
selumetinib study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - monocytes, percent viability dose: 1.235 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means98.9   %
Median of the strain means99.5   %
SD of the strain means± 10.3
Coefficient of variation (CV)0.104
Min–max range of strain means68.6   –   126   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 11929.0551 361.4865 3.0388 < 0.0001
Residuals 99 11776.8702 118.9583


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 126.0 29.5   4 14.8 0.234 82.1, 142.0 2.62
129X1/SvJ m 99.0 1.57   4 0.784 0.0158 96.8, 100.0 0.01
A/J m 100.0 5.34   4 2.67 0.0532 94.1, 106.0 0.1
AKR/J m 102.0 4.08   4 2.04 0.04 96.1, 105.0 0.3
BALB/cByJ m 106.0 2.48   4 1.24 0.0234 103.0, 109.0 0.69
BTBR T+ Itpr3tf/J m 85.0 10.1   4 5.07 0.119 75.6, 96.4 -1.35
BUB/BnJ m 93.5 3.87   4 1.94 0.0414 88.6, 98.0 -0.53
C3H/HeJ m 99.5 2.08   4 1.04 0.0209 96.8, 101.0 0.06
C57BL/6J m 101.0 1.43   4 0.713 0.0141 99.9, 103.0 0.2
C57BLKS/J m 86.8 10.2   4 5.1 0.117 73.1, 97.6 -1.18
C58/J m 68.6 2.86   2   2.03 0.0417 66.6, 70.6 -2.94
CBA/J m 91.2 11.5   4 5.77 0.127 79.1, 103.0 -0.75
CZECHII/EiJ m 103.0 9.8   4 4.9 0.0949 94.4, 115.0 0.39
DBA/2J m 101.0 22.5   4 11.2 0.223 86.2, 134.0 0.2
FVB/NJ m 102.0 3.86   4 1.93 0.038 98.7, 107.0 0.3
I/LnJ m 105.0 3.83   4 1.92 0.0365 99.9, 108.0 0.59
KK/HlJ m 99.0 1.51   4 0.756 0.0153 97.3, 101.0 0.01
LG/J m 100.0 7.76   4 3.88 0.0775 94.7, 112.0 0.1
LP/J m 102.0 1.83   4 0.914 0.0179 99.2, 103.0 0.3
MA/MyJ m 98.7 1.13   4 0.565 0.0114 97.3, 99.9 -0.02
NOD/ShiLtJ m 96.1 10.7   4 5.37 0.112 84.7, 111.0 -0.27
NON/ShiLtJ m 89.6 21.6   4 10.8 0.241 64.5, 113.0 -0.9
NZB/BlNJ m 102.0 1.74   4 0.871 0.0171 99.4, 104.0 0.3
NZO/HlLtJ m 95.8 5.43   4 2.72 0.0567 88.7, 101.0 -0.3
NZW/LacJ m 86.6 7.04   4 3.52 0.0813 78.0, 93.4 -1.2
PERA/EiJ m 117.0 9.83   4 4.91 0.0838 104.0, 127.0 1.75
PL/J m 98.6 5.86   4 2.93 0.0594 93.3, 105.0 -0.03
PWD/PhJ m 112.0 10.0   4 5.02 0.09 97.9, 122.0 1.27
PWK/PhJ m 95.8 7.75   4 3.87 0.0809 87.3, 106.0 -0.3
RIIIS/J m 98.4 9.76   4 4.88 0.0992 87.5, 111.0 -0.05
SEA/GnJ m 104.0 5.91   4 2.95 0.0569 95.0, 108.0 0.49
SJL/J m 115.0 14.7   4 7.33 0.128 96.6, 129.0 1.56
SM/J m 99.6 4.05   4 2.03 0.0407 94.1, 104.0 0.06
WSB/EiJ m 83.9 30.5   3 17.6 0.364 55.6, 116.0 -1.46


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 126.315 5.4534 137.1357 115.4943
129X1/SvJ m 98.955 5.4534 109.7757 88.1343
A/J m 100.455 5.4534 111.2757 89.6343
AKR/J m 102.1775 5.4534 112.9982 91.3568
BALB/cByJ m 105.8925 5.4534 116.7132 95.0718
BTBR T+ Itpr3tf/J m 84.9625 5.4534 95.7832 74.1418
BUB/BnJ m 93.535 5.4534 104.3557 82.7143
C3H/HeJ m 99.5375 5.4534 110.3582 88.7168
C57BL/6J m 101.275 5.4534 112.0957 90.4543
C57BLKS/J m 86.8325 5.4534 97.6532 76.0118
C58/J m 68.595 7.7123 83.8978 53.2922
CBA/J m 91.195 5.4534 102.0157 80.3743
CZECHII/EiJ m 103.23 5.4534 114.0507 92.4093
DBA/2J m 100.815 5.4534 111.6357 89.9943
FVB/NJ m 101.5025 5.4534 112.3232 90.6818
I/LnJ m 104.9125 5.4534 115.7332 94.0918
KK/HlJ m 99.0225 5.4534 109.8432 88.2018
LG/J m 100.15 5.4534 110.9707 89.3293
LP/J m 101.8975 5.4534 112.7182 91.0768
MA/MyJ m 98.74 5.4534 109.5607 87.9193
NOD/ShiLtJ m 96.0825 5.4534 106.9032 85.2618
NON/ShiLtJ m 89.625 5.4534 100.4457 78.8043
NZB/BlNJ m 101.72 5.4534 112.5407 90.8993
NZO/HlLtJ m 95.7975 5.4534 106.6182 84.9768
NZW/LacJ m 86.6425 5.4534 97.4632 75.8218
PERA/EiJ m 117.35 5.4534 128.1707 106.5293
PL/J m 98.6475 5.4534 109.4682 87.8268
PWD/PhJ m 111.6025 5.4534 122.4232 100.7818
PWK/PhJ m 95.7625 5.4534 106.5832 84.9418
RIIIS/J m 98.4375 5.4534 109.2582 87.6168
SEA/GnJ m 103.7725 5.4534 114.5932 92.9518
SJL/J m 114.535 5.4534 125.3557 103.7143
SM/J m 99.6275 5.4534 110.4482 88.8068
WSB/EiJ m 83.8967 6.297 96.3914 71.402




  GWAS USING LINEAR MIXED MODELS