Project measure / variable:   Wiltshire4   Bcells_BEZ_B

ID, description, units MPD:52403   Bcells_BEZ_B   B cells, percent viability   [%]  dose: 0.137 µM  
BEZ235 study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - B cells, percent viability dose: 0.137 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means104   %
Median of the strain means100   %
SD of the strain means± 15.2
Coefficient of variation (CV)0.147
Min–max range of strain means84.7   –   167   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 30125.8275 912.9039 1.8032 0.0137
Residuals 99 50119.3202 506.2558


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 113.0 12.6   4 6.31 0.112 98.4, 129.0 0.6
129X1/SvJ m 96.6 7.66   4 3.83 0.0793 86.2, 104.0 -0.47
A/J m 102.0 1.71   4 0.855 0.0167 102.0, 105.0 -0.12
AKR/J m 100.0 0.516   4 0.258 0.00514 99.8, 101.0 -0.25
BALB/cByJ m 100.0 4.1   4 2.05 0.0408 94.4, 103.0 -0.25
BTBR T+ Itpr3tf/J m 106.0 6.68   4 3.34 0.0633 96.5, 112.0 0.14
BUB/BnJ m 104.0 10.7   4 5.35 0.103 91.9, 116.0 0.01
C3H/HeJ m 93.6 6.46   4 3.23 0.069 85.5, 100.0 -0.67
C57BL/6J m 102.0 1.07   4 0.537 0.0106 100.0, 103.0 -0.12
C57BLKS/J m 106.0 9.18   4 4.59 0.0869 97.4, 117.0 0.14
C58/J m 88.0 1.13   2   0.8 0.0129 87.2, 88.8 -1.04
CBA/J m 124.0 43.0   4 21.5 0.346 85.8, 184.0 1.33
CZECHII/EiJ m 100.0 43.6   4 21.8 0.434 66.7, 163.0 -0.25
DBA/2J m 132.0 56.9   4 28.5 0.431 51.2, 176.0 1.85
FVB/NJ m 105.0 9.98   4 4.99 0.0951 90.5, 113.0 0.08
I/LnJ m 94.5 12.8   4 6.41 0.136 77.9, 105.0 -0.61
KK/HlJ m 104.0 6.8   4 3.4 0.0655 94.5, 109.0 0.01
LG/J m 91.4 61.8   4 30.9 0.676 -0.82
LP/J m 110.0 14.6   4 7.31 0.133 92.8, 128.0 0.41
MA/MyJ m 97.3 2.78   4 1.39 0.0286 93.6, 99.9 -0.43
NOD/ShiLtJ m 102.0 15.2   4 7.61 0.15 84.2, 121.0 -0.12
NON/ShiLtJ m 106.0 15.5   4 7.76 0.146 91.7, 124.0 0.14
NZB/BlNJ m 96.9 3.55   4 1.78 0.0366 92.9, 101.0 -0.45
NZO/HlLtJ m 84.8 14.9   4 7.47 0.176 67.2, 101.0 -1.25
NZW/LacJ m 84.7 28.0   4 14.0 0.33 60.0, 122.0 -1.26
PERA/EiJ m 126.0 39.0   4 19.5 0.31 102.0, 184.0 1.46
PL/J m 99.4 12.6   4 6.32 0.127 89.0, 116.0 -0.29
PWD/PhJ m 167.0 20.9   4 10.5 0.125 146.0, 195.0 4.15
PWK/PhJ m 95.9 9.01   4 4.51 0.094 84.9, 103.0 -0.52
RIIIS/J m 97.6 3.24   4 1.62 0.0332 94.4, 102.0 -0.41
SEA/GnJ m 95.7 8.67   4 4.34 0.0906 86.3, 107.0 -0.53
SJL/J m 109.0 29.4   4 14.7 0.27 91.8, 152.0 0.34
SM/J m 95.3 7.89   4 3.94 0.0828 86.1, 102.0 -0.56
WSB/EiJ m 100.0 14.7   3 8.48 0.147 87.7, 116.0 -0.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 112.8925 11.2501 135.2151 90.5699
129X1/SvJ m 96.5625 11.2501 118.8851 74.2399
A/J m 102.465 11.2501 124.7876 80.1424
AKR/J m 100.4825 11.2501 122.8051 78.1599
BALB/cByJ m 100.385 11.2501 122.7076 78.0624
BTBR T+ Itpr3tf/J m 105.53 11.2501 127.8526 83.2074
BUB/BnJ m 103.85 11.2501 126.1726 81.5274
C3H/HeJ m 93.5525 11.2501 115.8751 71.2299
C57BL/6J m 101.5575 11.2501 123.8801 79.2349
C57BLKS/J m 105.575 11.2501 127.8976 83.2524
C58/J m 87.96 15.91 119.5289 56.3911
CBA/J m 124.3725 11.2501 146.6951 102.0499
CZECHII/EiJ m 100.455 11.2501 122.7776 78.1324
DBA/2J m 132.02 11.2501 154.3426 109.6974
FVB/NJ m 105.005 11.2501 127.3276 82.6824
I/LnJ m 94.46 11.2501 116.7826 72.1374
KK/HlJ m 103.8675 11.2501 126.1901 81.5449
LG/J m 91.385 11.2501 113.7076 69.0624
LP/J m 109.8725 11.2501 132.1951 87.5499
MA/MyJ m 97.3025 11.2501 119.6251 74.9799
NOD/ShiLtJ m 101.83 11.2501 124.1526 79.5074
NON/ShiLtJ m 106.1125 11.2501 128.4351 83.7899
NZB/BlNJ m 96.94 11.2501 119.2626 74.6174
NZO/HlLtJ m 84.7925 11.2501 107.1151 62.4699
NZW/LacJ m 84.7075 11.2501 107.0301 62.3849
PERA/EiJ m 125.905 11.2501 148.2276 103.5824
PL/J m 99.445 11.2501 121.7676 77.1224
PWD/PhJ m 167.1775 11.2501 189.5001 144.8549
PWK/PhJ m 95.8625 11.2501 118.1851 73.5399
RIIIS/J m 97.555 11.2501 119.8776 75.2324
SEA/GnJ m 95.71 11.2501 118.0326 73.3874
SJL/J m 108.5225 11.2501 130.8451 86.1999
SM/J m 95.2525 11.2501 117.5751 72.9299
WSB/EiJ m 99.9967 12.9905 125.7725 74.2208




  GWAS USING LINEAR MIXED MODELS