Project measure / variable:   Wiltshire4   monocytes_Ida_E

ID, description, units MPD:52458   monocytes_Ida_E   monocytes, percent viability   [%]  dose: 100 µM  
idarubicin study
Data set, strains Wiltshire4   inbred w/CC7   35 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - monocytes, percent viability dose: 100 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means15.9   %
Median of the strain means10.7   %
SD of the strain means± 13.0
Coefficient of variation (CV)0.818
Min–max range of strain means1.73   –   48.3   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 22629.5501 665.575 4.1022 < 0.0001
Residuals 102 16549.3296 162.2483


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 6.37 3.82   4 1.91 0.599 2.36, 11.5 -0.73
129X1/SvJ m 28.6 10.3   4 5.13 0.359 19.1, 42.2 0.98
A/J m 46.9 14.8   4 7.39 0.315 34.3, 67.3 2.39
AKR/J m 35.4 5.2   4 2.6 0.147 30.3, 41.1 1.51
BALB/cByJ m 5.19 0.843   4 0.421 0.162 4.31, 6.33 -0.82
BTBR T+ Itpr3tf/J m 9.69 5.12   4 2.56 0.528 2.82, 14.3 -0.48
C3H/HeJ m 12.3 7.85   4 3.92 0.636 2.61, 20.6 -0.27
C57BL/6J m 18.2 8.74   4 4.37 0.479 9.15, 29.5 0.18
C57BLKS/J m 14.6 8.46   4 4.23 0.579 2.88, 21.3 -0.1
C57BR/cdJ m 8.66 9.36   4 4.68 1.08 -0.55
C58/J m 5.65 2.28   2   1.62 0.404 4.04, 7.27 -0.79
CBA/J m 8.28 3.62   4 1.81 0.437 5.71, 13.6 -0.58
CZECHII/EiJ m 12.8 2.77   4 1.39 0.217 9.76, 16.4 -0.24
DBA/2J m 19.4 10.9   4 5.47 0.565 6.33, 33.1 0.27
FVB/NJ m 18.5 9.9   4 4.95 0.536 8.02, 31.9 0.2
I/LnJ m 33.1 49.5   4 24.8 1.5 5.38, 107.0 1.33
KK/HlJ m 24.4 21.7   4 10.8 0.886 0.66
LG/J m 8.34 2.12   4 1.06 0.255 5.22, 9.96 -0.58
LP/J m 10.0 4.45   4 2.23 0.445 3.95, 14.3 -0.45
MA/MyJ m 3.58 1.34   4 0.671 0.374 2.29, 5.33 -0.95
NOD/ShiLtJ m 9.68 5.39   4 2.7 0.557 2.26, 15.2 -0.48
NON/ShiLtJ m 48.3 18.1   4 9.06 0.375 25.1, 68.9 2.5
NZB/BlNJ m 17.2 3.36   4 1.68 0.196 13.8, 21.5 0.1
NZO/HlLtJ m 4.48 1.03   4 0.514 0.229 3.07, 5.51 -0.88
NZW/LacJ m 4.6 1.35   4 0.677 0.294 3.4, 6.51 -0.87
PERA/EiJ m 6.31 2.3   4 1.15 0.365 4.66, 9.61 -0.74
PL/J m 8.9 4.32   4 2.16 0.486 4.94, 15.0 -0.54
PWD/PhJ m 2.22 2.91   4 1.46 1.31 -1.05
PWK/PhJ m 1.73 1.3   4 0.648 0.748 -1.09
RIIIS/J m 4.71 5.44   4 2.72 1.16 -0.86
SEA/GnJ m 44.8 19.8   4 9.88 0.441 25.5, 63.3 2.23
SJL/J m 20.1 16.0   4 8.02 0.798 4.9, 42.2 0.33
SM/J m 10.7 6.73   4 3.36 0.63 5.33, 20.0 -0.4
SWR/J m 29.7 19.9   4 9.97 0.671 9.54, 56.2 1.07
WSB/EiJ m 11.4 12.9   3 7.46 1.14 3.49, 26.3 -0.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 6.37 6.3688 19.0026 0.0
129X1/SvJ m 28.6 6.3688 41.2326 15.9674
A/J m 46.8875 6.3688 59.5201 34.2549
AKR/J m 35.3875 6.3688 48.0201 22.7549
BALB/cByJ m 5.1925 6.3688 17.8251 0.0
BTBR T+ Itpr3tf/J m 9.69 6.3688 22.3226 0.0
C3H/HeJ m 12.34 6.3688 24.9726 0.0
C57BL/6J m 18.24 6.3688 30.8726 5.6074
C57BLKS/J m 14.6 6.3688 27.2326 1.9674
C57BR/cdJ m 8.66 6.3688 21.2926 0.0
C58/J m 5.655 9.0069 23.5201 0.0
CBA/J m 8.275 6.3688 20.9076 0.0
CZECHII/EiJ m 12.795 6.3688 25.4276 0.1624
DBA/2J m 19.3625 6.3688 31.9951 6.7299
FVB/NJ m 18.46 6.3688 31.0926 5.8274
I/LnJ m 33.055 6.3688 45.6876 20.4224
KK/HlJ m 24.44 6.3688 37.0726 11.8074
LG/J m 8.3375 6.3688 20.9701 0.0
LP/J m 10.005 6.3688 22.6376 0.0
MA/MyJ m 3.585 6.3688 16.2176 0.0
NOD/ShiLtJ m 9.6775 6.3688 22.3101 0.0
NON/ShiLtJ m 48.3175 6.3688 60.9501 35.6849
NZB/BlNJ m 17.1725 6.3688 29.8051 4.5399
NZO/HlLtJ m 4.485 6.3688 17.1176 0.0
NZW/LacJ m 4.6 6.3688 17.2326 0.0
PERA/EiJ m 6.315 6.3688 18.9476 0.0
PL/J m 8.9025 6.3688 21.5351 0.0
PWD/PhJ m 2.2175 6.3688 14.8501 0.0
PWK/PhJ m 1.7325 6.3688 14.3651 0.0
RIIIS/J m 4.705 6.3688 17.3376 0.0
SEA/GnJ m 44.81 6.3688 57.4426 32.1774
SJL/J m 20.0975 6.3688 32.7301 7.4649
SM/J m 10.675 6.3688 23.3076 0.0
SWR/J m 29.735 6.3688 42.3676 17.1024
WSB/EiJ m 11.3767 7.3541 25.9635 0.0




  GWAS USING LINEAR MIXED MODELS