Project measure / variable:   Wiltshire4   Bcells_Ida_D

ID, description, units MPD:52445   Bcells_Ida_D   B cells, percent viability   [%]  dose: 11.1 µM  
idarubicin study
Data set, strains Wiltshire4   inbred w/CC7   35 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - B cells, percent viability dose: 11.1 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means17.7   %
Median of the strain means13.6   %
SD of the strain means± 15.3
Coefficient of variation (CV)0.863
Min–max range of strain means0.665   –   58.8   %
Mean sample size per strain3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 29982.7478 881.8455 4.1583 < 0.0001
Residuals 101 21419.1621 212.0709


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 16.9 6.78   4 3.39 0.402 8.34, 24.6 -0.05
129X1/SvJ m 58.8 16.6   4 8.31 0.283 41.6, 76.2 2.69
A/J m 1.59 0.699   4 0.349 0.438 1.1, 2.63 -1.05
AKR/J m 26.7 11.1   4 5.57 0.417 11.4, 37.5 0.59
BALB/cByJ m 48.9 5.45   4 2.73 0.111 44.7, 56.9 2.04
BTBR T+ Itpr3tf/J m 10.6 6.7   3 3.87 0.629 4.23, 17.6 -0.47
C3H/HeJ m 28.9 5.13   4 2.56 0.178 21.9, 34.0 0.73
C57BL/6J m 17.2 15.0   4 7.51 0.875 2.65, 35.8 -0.03
C57BLKS/J m 2.83 0.682   4 0.341 0.241 1.93, 3.36 -0.97
C57BR/cdJ m 5.39 6.77   4 3.39 1.26 0.33, 15.1 -0.81
C58/J m 0.665 0.94   2   0.665 1.41 -1.12
CBA/J m 2.88 1.15   4 0.577 0.401 1.92, 4.49 -0.97
CZECHII/EiJ m 3.62 0.777   4 0.389 0.214 2.72, 4.62 -0.92
DBA/2J m 4.56 4.7   4 2.35 1.03 1.18, 11.5 -0.86
FVB/NJ m 19.4 5.65   4 2.82 0.291 16.1, 27.9 0.11
I/LnJ m 13.6 9.78   4 4.89 0.717 5.5, 25.5 -0.27
KK/HlJ m 28.8 10.7   4 5.35 0.371 13.5, 36.4 0.72
LG/J m 2.78 2.24   4 1.12 0.805 0.44, 5.54 -0.98
LP/J m 8.75 4.03   4 2.01 0.46 3.57, 12.5 -0.59
MA/MyJ m 6.43 4.79   4 2.39 0.745 1.66, 12.7 -0.74
NOD/ShiLtJ m 2.63 0.349   4 0.174 0.133 2.12, 2.91 -0.99
NON/ShiLtJ m 18.4 7.84   4 3.92 0.427 8.8, 26.8 0.04
NZB/BlNJ m 21.0 8.51   4 4.25 0.404 12.8, 29.1 0.21
NZO/HlLtJ m 9.98 8.69   4 4.34 0.87 0.56, 21.5 -0.51
NZW/LacJ m 12.1 8.35   4 4.17 0.691 0.84, 21.0 -0.37
PERA/EiJ m 34.3 64.8   4 32.4 1.89 1.08
PL/J m 35.7 17.9   4 8.93 0.5 22.2, 61.1 1.18
PWD/PhJ m 9.37 3.28   4 1.64 0.35 5.44, 13.1 -0.55
PWK/PhJ m 7.73 1.76   4 0.881 0.228 5.37, 9.64 -0.65
RIIIS/J m 7.26 1.88   4 0.939 0.259 4.92, 9.45 -0.68
SEA/GnJ m 14.4 12.4   4 6.18 0.856 3.04, 29.3 -0.22
SJL/J m 18.7 23.0   4 11.5 1.23 0.34, 48.3 0.06
SM/J m 37.7 14.8   4 7.38 0.391 29.5, 59.9 1.31
SWR/J m 29.5 5.48   4 2.74 0.186 23.5, 36.7 0.77
WSB/EiJ m 52.1 20.3   3 11.7 0.39 36.5, 75.1 2.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 16.8725 7.2813 31.3167 2.4283
129X1/SvJ m 58.82 7.2813 73.2642 44.3758
A/J m 1.595 7.2813 16.0392 0.0
AKR/J m 26.715 7.2813 41.1592 12.2708
BALB/cByJ m 48.885 7.2813 63.3292 34.4408
BTBR T+ Itpr3tf/J m 10.64 8.4078 27.3187 0.0
C3H/HeJ m 28.85 7.2813 43.2942 14.4058
C57BL/6J m 17.16 7.2813 31.6042 2.7158
C57BLKS/J m 2.83 7.2813 17.2742 0.0
C57BR/cdJ m 5.39 7.2813 19.8342 0.0
C58/J m 0.665 10.2974 21.0922 0.0
CBA/J m 2.8775 7.2813 17.3217 0.0
CZECHII/EiJ m 3.625 7.2813 18.0692 0.0
DBA/2J m 4.565 7.2813 19.0092 0.0
FVB/NJ m 19.4275 7.2813 33.8717 4.9833
I/LnJ m 13.6325 7.2813 28.0767 0.0
KK/HlJ m 28.825 7.2813 43.2692 14.3808
LG/J m 2.7775 7.2813 17.2217 0.0
LP/J m 8.7525 7.2813 23.1967 0.0
MA/MyJ m 6.43 7.2813 20.8742 0.0
NOD/ShiLtJ m 2.6275 7.2813 17.0717 0.0
NON/ShiLtJ m 18.38 7.2813 32.8242 3.9358
NZB/BlNJ m 21.045 7.2813 35.4892 6.6008
NZO/HlLtJ m 9.9825 7.2813 24.4267 0.0
NZW/LacJ m 12.0775 7.2813 26.5217 0.0
PERA/EiJ m 34.315 7.2813 48.7592 19.8708
PL/J m 35.7025 7.2813 50.1467 21.2583
PWD/PhJ m 9.37 7.2813 23.8142 0.0
PWK/PhJ m 7.7325 7.2813 22.1767 0.0
RIIIS/J m 7.2575 7.2813 21.7017 0.0
SEA/GnJ m 14.4425 7.2813 28.8867 0.0
SJL/J m 18.675 7.2813 33.1192 4.2308
SM/J m 37.7275 7.2813 52.1717 23.2833
SWR/J m 29.5 7.2813 43.9442 15.0558
WSB/EiJ m 52.1133 8.4078 68.7921 35.4346




  GWAS USING LINEAR MIXED MODELS