Project measure / variable:   Wiltshire4   monocytes_Sel_B

ID, description, units MPD:52475   monocytes_Sel_B   monocytes, percent viability   [%]  dose: 0.137 µM  
selumetinib study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Wiltshire4 - monocytes, percent viability dose: 0.137 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means97.4   %
Median of the strain means99.2   %
SD of the strain means± 8.98
Coefficient of variation (CV)0.0921
Min–max range of strain means72.2   –   113   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 9201.4133 278.8307 1.1654 0.2774
Residuals 99 23685.8259 239.2508


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 72.2 49.8   4 24.9 0.689 -2.81
129X1/SvJ m 98.8 3.23   4 1.62 0.0327 94.1, 101.0 0.15
A/J m 97.6 3.22   4 1.61 0.033 94.2, 102.0 0.02
AKR/J m 100.0 2.67   4 1.33 0.0265 96.6, 103.0 0.29
BALB/cByJ m 105.0 1.42   4 0.709 0.0136 103.0, 106.0 0.84
BTBR T+ Itpr3tf/J m 94.3 6.16   4 3.08 0.0653 87.9, 101.0 -0.35
BUB/BnJ m 94.3 5.41   4 2.71 0.0574 86.7, 98.6 -0.35
C3H/HeJ m 99.1 1.35   4 0.677 0.0137 97.8, 101.0 0.19
C57BL/6J m 103.0 1.95   4 0.977 0.019 99.7, 104.0 0.62
C57BLKS/J m 88.4 10.9   4 5.45 0.123 76.9, 103.0 -1.01
C58/J m 73.7 6.51   2   4.61 0.0884 69.1, 78.3 -2.64
CBA/J m 102.0 7.08   4 3.54 0.0692 95.3, 111.0 0.51
CZECHII/EiJ m 106.0 6.29   4 3.14 0.0593 98.0, 112.0 0.95
DBA/2J m 94.2 21.8   4 10.9 0.231 77.5, 126.0 -0.36
FVB/NJ m 97.9 5.27   4 2.63 0.0538 94.6, 106.0 0.05
I/LnJ m 103.0 3.29   4 1.64 0.0321 98.4, 106.0 0.62
KK/HlJ m 93.0 6.12   4 3.06 0.0658 87.2, 98.4 -0.49
LG/J m 105.0 5.93   4 2.96 0.0566 99.3, 112.0 0.84
LP/J m 100.0 2.48   4 1.24 0.0248 96.4, 102.0 0.29
MA/MyJ m 101.0 1.6   4 0.798 0.0158 98.3, 102.0 0.4
NOD/ShiLtJ m 94.3 18.7   4 9.33 0.198 70.4, 116.0 -0.35
NON/ShiLtJ m 95.0 14.7   4 7.34 0.155 76.6, 111.0 -0.27
NZB/BlNJ m 102.0 2.07   4 1.04 0.0204 98.6, 104.0 0.51
NZO/HlLtJ m 94.3 3.44   4 1.72 0.0365 90.5, 98.2 -0.35
NZW/LacJ m 86.8 10.1   4 5.04 0.116 75.5, 99.2 -1.18
PERA/EiJ m 112.0 21.4   4 10.7 0.191 98.5, 144.0 1.62
PL/J m 99.6 3.71   4 1.86 0.0372 94.2, 102.0 0.24
PWD/PhJ m 113.0 20.2   4 10.1 0.178 92.1, 141.0 1.73
PWK/PhJ m 91.4 7.59   4 3.8 0.0831 84.0, 99.8 -0.67
RIIIS/J m 109.0 30.5   4 15.2 0.28 80.9, 139.0 1.29
SEA/GnJ m 100.0 13.9   4 6.94 0.139 80.2, 110.0 0.29
SJL/J m 99.2 20.7   4 10.4 0.209 77.7, 121.0 0.2
SM/J m 104.0 1.83   4 0.914 0.0176 102.0, 106.0 0.73
WSB/EiJ m 83.8 44.6   3 25.8 0.532 38.1, 127.0 -1.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 72.23 7.7339 87.5757 56.8843
129X1/SvJ m 98.77 7.7339 114.1157 83.4243
A/J m 97.605 7.7339 112.9507 82.2593
AKR/J m 100.4975 7.7339 115.8432 85.1518
BALB/cByJ m 104.555 7.7339 119.9007 89.2093
BTBR T+ Itpr3tf/J m 94.335 7.7339 109.6807 78.9893
BUB/BnJ m 94.27 7.7339 109.6157 78.9243
C3H/HeJ m 99.0775 7.7339 114.4232 83.7318
C57BL/6J m 102.5775 7.7339 117.9232 87.2318
C57BLKS/J m 88.4275 7.7339 103.7732 73.0818
C58/J m 73.695 10.9373 95.3971 51.9929
CBA/J m 102.32 7.7339 117.6657 86.9743
CZECHII/EiJ m 105.965 7.7339 121.3107 90.6193
DBA/2J m 94.22 7.7339 109.5657 78.8743
FVB/NJ m 97.9025 7.7339 113.2482 82.5568
I/LnJ m 102.5525 7.7339 117.8982 87.2068
KK/HlJ m 92.9725 7.7339 108.3182 77.6268
LG/J m 104.695 7.7339 120.0407 89.3493
LP/J m 100.0275 7.7339 115.3732 84.6818
MA/MyJ m 100.6925 7.7339 116.0382 85.3468
NOD/ShiLtJ m 94.3475 7.7339 109.6932 79.0018
NON/ShiLtJ m 95.025 7.7339 110.3707 79.6793
NZB/BlNJ m 101.54 7.7339 116.8857 86.1943
NZO/HlLtJ m 94.2975 7.7339 109.6432 78.9518
NZW/LacJ m 86.805 7.7339 102.1507 71.4593
PERA/EiJ m 111.92 7.7339 127.2657 96.5743
PL/J m 99.6275 7.7339 114.9732 84.2818
PWD/PhJ m 113.21 7.7339 128.5557 97.8643
PWK/PhJ m 91.4075 7.7339 106.7532 76.0618
RIIIS/J m 108.7475 7.7339 124.0932 93.4018
SEA/GnJ m 100.18 7.7339 115.5257 84.8343
SJL/J m 99.2275 7.7339 114.5732 83.8818
SM/J m 103.9025 7.7339 119.2482 88.5568
WSB/EiJ m 83.84 8.9303 101.5597 66.1203




  GWAS USING LINEAR MIXED MODELS