Project measure / variable:   Wiltshire4   Bcells_Dox_E

ID, description, units MPD:52426   Bcells_Dox_E   B cells, percent viability   [%]  dose: 100 µM  
doxorubicin study
Data set, strains Wiltshire4   inbred w/CC7   35 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - B cells, percent viability dose: 100 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means13.9   %
Median of the strain means10.4   %
SD of the strain means± 13.7
Coefficient of variation (CV)0.986
Min–max range of strain means0.943   –   50.1   %
Mean sample size per strain3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 23577.9217 714.4825 8.556 < 0.0001
Residuals 99 8267.179 83.5069


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 29.3 5.38   4 2.69 0.184 25.0, 37.0 1.12
129X1/SvJ m 23.4 11.8   4 5.89 0.503 11.8, 38.3 0.69
A/J m 11.8 3.9   4 1.95 0.331 7.51, 17.0 -0.15
AKR/J m 26.6 5.7   4 2.85 0.214 20.3, 33.0 0.92
BALB/cByJ m 16.6 5.99   4 2.99 0.362 11.9, 25.1 0.2
BTBR T+ Itpr3tf/J m 2.67 0.902   4 0.451 0.339 1.78, 3.62 -0.82
C3H/HeJ m 3.48 1.1   4 0.549 0.315 1.97, 4.48 -0.76
C57BL/6J m 3.12 1.73   4 0.863 0.553 1.3, 5.43 -0.79
C57BLKS/J m 5.1 1.68   4 0.839 0.329 3.43, 6.76 -0.64
C57BR/cdJ m 2.52 0.922   4 0.461 0.367 1.19, 3.23 -0.83
C58/J m 4.12 1.28   2   0.905 0.311 3.21, 5.02 -0.71
CBA/J m 19.0 28.4   4 14.2 1.49 2.42, 61.6 0.37
CZECHII/EiJ m 2.72 1.02   4 0.511 0.375 1.92, 4.2 -0.82
DBA/2J m 38.0 19.5   4 9.75 0.513 17.8, 55.9 1.76
FVB/NJ m 23.4 11.4   4 5.7 0.487 15.3, 39.7 0.69
I/LnJ m 2.66 0.0   1   0.0 0.0 2.66, 2.66 -0.82
KK/HlJ m 0.943 1.89   4 0.943 2.0 -0.95
LG/J m 2.76 1.28   4 0.64 0.464 1.43, 4.0 -0.81
LP/J m 2.35 1.8   4 0.898 0.764 0.87, 4.86 -0.84
MA/MyJ m 3.45 3.65   4 1.83 1.06 1.2, 8.89 -0.76
NOD/ShiLtJ m 4.05 1.12   4 0.558 0.275 2.98, 5.4 -0.72
NON/ShiLtJ m 16.2 6.13   4 3.06 0.378 9.23, 23.7 0.17
NZB/BlNJ m 10.6 10.2   4 5.1 0.962 1.52, 24.4 -0.24
NZO/HlLtJ m 3.11 1.82   4 0.911 0.585 1.26, 5.54 -0.79
NZW/LacJ m 2.51 0.968   4 0.484 0.385 1.29, 3.31 -0.83
PERA/EiJ m 3.08 2.13   4 1.06 0.689 1.25, 5.84 -0.79
PL/J m 20.6 4.51   4 2.25 0.219 16.3, 25.7 0.49
PWD/PhJ m 46.4 14.6   4 7.28 0.314 28.6, 63.5 2.37
PWK/PhJ m 15.5 5.25   4 2.62 0.338 7.87, 19.0 0.12
RIIIS/J m 4.36 3.29   4 1.64 0.755 1.39, 9.0 -0.7
SEA/GnJ m 22.7 4.45   4 2.22 0.196 17.2, 27.0 0.64
SJL/J m 13.2 9.96   4 4.98 0.752 4.3, 27.0 -0.05
SM/J m 10.4 6.44   4 3.22 0.619 4.49, 16.8 -0.26
SWR/J m 40.2 14.5   4 7.26 0.361 29.7, 61.6 1.92
WSB/EiJ m 50.1 23.3   3 13.4 0.464 34.7, 76.9 2.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 29.2775 4.5691 38.3436 20.2114
129X1/SvJ m 23.41 4.5691 32.4761 14.3439
A/J m 11.7825 4.5691 20.8486 2.7164
AKR/J m 26.6175 4.5691 35.6836 17.5514
BALB/cByJ m 16.56 4.5691 25.6261 7.4939
BTBR T+ Itpr3tf/J m 2.665 4.5691 11.7311 0.0
C3H/HeJ m 3.485 4.5691 12.5511 0.0
C57BL/6J m 3.1225 4.5691 12.1886 0.0
C57BLKS/J m 5.095 4.5691 14.1611 0.0
C57BR/cdJ m 2.515 4.5691 11.5811 0.0
C58/J m 4.115 6.4617 16.9364 0.0
CBA/J m 19.0225 4.5691 28.0886 9.9564
CZECHII/EiJ m 2.7225 4.5691 11.7886 0.0
DBA/2J m 37.9925 4.5691 47.0586 28.9264
FVB/NJ m 23.39 4.5691 32.4561 14.3239
KK/HlJ m 0.9425 4.5691 10.0086 0.0
LG/J m 2.76 4.5691 11.8261 0.0
LP/J m 2.3525 4.5691 11.4186 0.0
MA/MyJ m 3.4475 4.5691 12.5136 0.0
NOD/ShiLtJ m 4.0525 4.5691 13.1186 0.0
NON/ShiLtJ m 16.215 4.5691 25.2811 7.1489
NZB/BlNJ m 10.61 4.5691 19.6761 1.5439
NZO/HlLtJ m 3.1125 4.5691 12.1786 0.0
NZW/LacJ m 2.515 4.5691 11.5811 0.0
PERA/EiJ m 3.085 4.5691 12.1511 0.0
PL/J m 20.565 4.5691 29.6311 11.4989
PWD/PhJ m 46.3525 4.5691 55.4186 37.2864
PWK/PhJ m 15.5275 4.5691 24.5936 6.4614
RIIIS/J m 4.355 4.5691 13.4211 0.0
SEA/GnJ m 22.6875 4.5691 31.7536 13.6214
SJL/J m 13.25 4.5691 22.3161 4.1839
SM/J m 10.4025 4.5691 19.4686 1.3364
SWR/J m 40.2175 4.5691 49.2836 31.1514
WSB/EiJ m 50.12 5.2759 60.5886 39.6514




  GWAS USING LINEAR MIXED MODELS