Project measure / variable:   Wiltshire4   monocytes_Dox_A

ID, description, units MPD:52434   monocytes_Dox_A   monocytes, percent viability   [%]  dose: 0.046 µM  
doxorubicin study
Data set, strains Wiltshire4   inbred w/CC7   35 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - monocytes, percent viability dose: 0.046 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means91.2   %
Median of the strain means93.7   %
SD of the strain means± 9.92
Coefficient of variation (CV)0.109
Min–max range of strain means63.7   –   105   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 13202.7055 388.3149 2.4379 0.0003
Residuals 102 16246.6196 159.2806


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 97.9 44.5   4 22.2 0.454 61.6, 163.0 0.67
129X1/SvJ m 97.0 4.57   4 2.28 0.0471 91.4, 102.0 0.58
A/J m 86.3 7.14   4 3.57 0.0827 80.0, 95.4 -0.5
AKR/J m 91.8 7.01   4 3.5 0.0763 83.6, 97.7 0.06
BALB/cByJ m 96.0 1.94   4 0.972 0.0202 93.5, 98.2 0.48
BTBR T+ Itpr3tf/J m 94.1 12.8   4 6.39 0.136 81.5, 110.0 0.29
C3H/HeJ m 94.3 1.6   4 0.801 0.017 92.8, 96.2 0.31
C57BL/6J m 93.7 6.6   4 3.3 0.0705 89.0, 103.0 0.25
C57BLKS/J m 67.9 2.95   4 1.48 0.0435 64.5, 71.7 -2.35
C57BR/cdJ m 83.1 7.63   4 3.81 0.0918 75.4, 92.6 -0.82
C58/J m 90.4 0.559   2   0.395 0.00618 90.0, 90.8 -0.08
CBA/J m 82.5 5.17   4 2.59 0.0627 77.8, 89.1 -0.88
CZECHII/EiJ m 87.9 7.39   4 3.7 0.0841 79.7, 94.2 -0.34
DBA/2J m 63.7 8.05   4 4.03 0.126 57.6, 75.5 -2.78
FVB/NJ m 88.1 8.47   4 4.24 0.0962 79.0, 99.4 -0.32
I/LnJ m 97.4 11.4   4 5.7 0.117 81.5, 108.0 0.62
KK/HlJ m 78.8 9.83   4 4.91 0.125 66.4, 87.8 -1.25
LG/J m 102.0 5.1   4 2.55 0.0499 94.7, 106.0 1.09
LP/J m 86.3 2.9   4 1.45 0.0337 82.1, 88.5 -0.5
MA/MyJ m 97.7 2.96   4 1.48 0.0303 93.8, 100.0 0.65
NOD/ShiLtJ m 102.0 8.86   4 4.43 0.0873 91.8, 113.0 1.09
NON/ShiLtJ m 70.9 12.4   4 6.18 0.175 54.4, 84.2 -2.05
NZB/BlNJ m 89.7 10.8   4 5.38 0.12 74.2, 97.5 -0.15
NZO/HlLtJ m 102.0 2.67   4 1.34 0.0262 99.9, 106.0 1.09
NZW/LacJ m 98.5 10.1   4 5.06 0.103 85.8, 110.0 0.73
PERA/EiJ m 98.9 13.1   4 6.56 0.133 88.2, 118.0 0.77
PL/J m 100.0 0.717   4 0.358 0.00714 99.6, 101.0 0.88
PWD/PhJ m 90.8 14.7   4 7.33 0.161 73.3, 105.0 -0.04
PWK/PhJ m 92.1 18.7   4 9.33 0.203 64.4, 104.0 0.09
RIIIS/J m 97.3 11.9   4 5.95 0.122 86.5, 114.0 0.61
SEA/GnJ m 89.7 1.36   4 0.681 0.0152 87.7, 90.7 -0.15
SJL/J m 79.7 14.2   4 7.12 0.178 62.7, 97.4 -1.16
SM/J m 97.6 4.88   4 2.44 0.05 91.8, 104.0 0.64
SWR/J m 102.0 12.2   4 6.09 0.119 86.7, 115.0 1.09
WSB/EiJ m 105.0 35.4   3 20.4 0.337 80.2, 146.0 1.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 97.9425 6.3103 110.459 85.426
129X1/SvJ m 97.0275 6.3103 109.544 84.511
A/J m 86.3375 6.3103 98.854 73.821
AKR/J m 91.84 6.3103 104.3565 79.3235
BALB/cByJ m 96.025 6.3103 108.5415 83.5085
BTBR T+ Itpr3tf/J m 94.1225 6.3103 106.639 81.606
C3H/HeJ m 94.3225 6.3103 106.839 81.806
C57BL/6J m 93.675 6.3103 106.1915 81.1585
C57BLKS/J m 67.9025 6.3103 80.419 55.386
C57BR/cdJ m 83.09 6.3103 95.6065 70.5735
C58/J m 90.445 8.9241 108.146 72.744
CBA/J m 82.495 6.3103 95.0115 69.9785
CZECHII/EiJ m 87.855 6.3103 100.3715 75.3385
DBA/2J m 63.6925 6.3103 76.209 51.176
FVB/NJ m 88.0925 6.3103 100.609 75.576
I/LnJ m 97.415 6.3103 109.9315 84.8985
KK/HlJ m 78.8275 6.3103 91.344 66.311
LG/J m 102.0725 6.3103 114.589 89.556
LP/J m 86.2775 6.3103 98.794 73.761
MA/MyJ m 97.7475 6.3103 110.264 85.231
NOD/ShiLtJ m 101.55 6.3103 114.0665 89.0335
NON/ShiLtJ m 70.86 6.3103 83.3765 58.3435
NZB/BlNJ m 89.735 6.3103 102.2515 77.2185
NZO/HlLtJ m 101.8775 6.3103 114.394 89.361
NZW/LacJ m 98.4575 6.3103 110.974 85.941
PERA/EiJ m 98.925 6.3103 111.4415 86.4085
PL/J m 100.3875 6.3103 112.904 87.871
PWD/PhJ m 90.845 6.3103 103.3615 78.3285
PWK/PhJ m 92.0525 6.3103 104.569 79.536
RIIIS/J m 97.2625 6.3103 109.779 84.746
SEA/GnJ m 89.71 6.3103 102.2265 77.1935
SJL/J m 79.7325 6.3103 92.249 67.216
SM/J m 97.645 6.3103 110.1615 85.1285
SWR/J m 102.2375 6.3103 114.754 89.721
WSB/EiJ m 104.96 7.2865 119.4128 90.5072




  GWAS USING LINEAR MIXED MODELS