Phenotype measure:   Lake2   hindlimb_rotation

ID, description, units MPD:21718   hindlimb_rotation   response to rotation while held in extension by the tail with forelimbs gripping (wire maneuver) (score 0-4)   [score]
Data set, strains Lake2   B6.A consomic w/par   23 strains     sex: both     age: 8wks
Procedure observation (SHIRPA)
Ontology mappings

  STRAIN COMPARISON PLOT
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Lake2 - response to rotation while held in extension by the tail with forelimbs gripping (wire maneuver) (score 0-4)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains23 strains
Mean of the strain means0.296   score 0.441   score
Median of the strain means0.250   score 0.500   score
SD of the strain means± 0.396 ± 0.406
Coefficient of variation (CV)1.34 0.922
Min–max range of strain means0   –   1.75   score 0   –   1.50   score
Mean sample size per strain8.3   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.5172 2.5172 5.8642 0.016
strain 22 34.9591 1.589 3.702 < 0.0001
sex:strain 22 22.4666 1.0212 2.3791 0.0006
Residuals 335 143.7946 0.4292


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 0.0 0.0   16 0.0 0.0 -0.75
A/J m 0.0 0.0   8 0.0 0.0 -1.08
B6.A-Chr1 f 0.0 0.0   8 0.0 0.0 -0.75
B6.A-Chr1 m 0.5 0.535   8 0.189 1.07 0.15
B6.A-Chr10 f 0.5 0.535   8 0.189 1.07 0.51
B6.A-Chr10 m 0.75 0.463   8 0.164 0.617 0.76
B6.A-Chr11 f 0.375 0.518   8 0.183 1.38 0.2
B6.A-Chr11 m 0.5 0.527   10 0.167 1.05 0.15
B6.A-Chr12 f 0.25 0.707   8 0.25 2.83 -0.12
B6.A-Chr12 m 1.0 1.41   8 0.5 1.41 1.38
B6.A-Chr13 f 0.0 0.0   5 0.0 0.0 -0.75
B6.A-Chr13 m 0.143 0.378   7 0.143 2.65 -0.73
B6.A-Chr14 f 0.125 0.354   8 0.125 2.83 -0.43
B6.A-Chr14 m 0.125 0.354   8 0.125 2.83 -0.78
B6.A-Chr15 f 0.75 0.707   8 0.25 0.943 1.15
B6.A-Chr15 m 0.125 0.354   8 0.125 2.83 -0.78
B6.A-Chr16 f 0.125 0.354   8 0.125 2.83 -0.43
B6.A-Chr16 m 0.875 1.13   8 0.398 1.29 1.07
B6.A-Chr17 f 0.25 0.463   8 0.164 1.85 -0.12
B6.A-Chr17 m 0.625 1.41   8 0.498 2.25 0.45
B6.A-Chr18 f 0.25 0.463   8 0.164 1.85 -0.12
B6.A-Chr18 m 1.12 1.25   8 0.441 1.11 1.67
B6.A-Chr19 f 0.75 1.04   8 0.366 1.38 1.15
B6.A-Chr19 m 0.125 0.354   8 0.125 2.83 -0.78
B6.A-Chr2 f 0.375 0.518   8 0.183 1.38 0.2
B6.A-Chr2 m 0.625 0.744   8 0.263 1.19 0.45
B6.A-Chr3 f 0.375 0.518   8 0.183 1.38 0.2
B6.A-Chr3 m 0.375 0.518   8 0.183 1.38 -0.16
B6.A-Chr4 f 0.0 0.0   7 0.0 0.0 -0.75
B6.A-Chr4 m 0.5 1.41   8 0.5 2.83 0.15
B6.A-Chr5 f 0.375 0.518   8 0.183 1.38 0.2
B6.A-Chr5 m 0.5 0.535   8 0.189 1.07 0.15
B6.A-Chr6 f 1.75 1.16   8 0.412 0.666 1.0, 4.0 3.67
B6.A-Chr6 m 0.5 0.535   8 0.189 1.07 0.15
B6.A-Chr7 f 0.0 0.0   8 0.0 0.0 -0.75
B6.A-Chr7 m 0.0 0.0   8 0.0 0.0 -1.08
B6.A-Chr8 f 0.5 0.756   8 0.267 1.51 0.51
B6.A-Chr8 m 1.5 1.6   8 0.567 1.07 2.61
B6.A-Chr9 f 0.0 0.0   8 0.0 0.0 -0.75
B6.A-Chr9 m 0.125 0.354   8 0.125 2.83 -0.78
B6.A-ChrX f 0.0 0.0   8 0.0 0.0 -0.75
B6.A-ChrX m 0.0 0.0   8 0.0 0.0 -1.08
B6.A-ChrY f 0.0 0.0   8 0.0 0.0 -0.75
B6.A-ChrY m 0.125 0.354   8 0.125 2.83 -0.78
C57BL/6J f 0.0625 0.25   16 0.0625 4.0 -0.59
C57BL/6J m 0.0 0.0   8 0.0 0.0 -1.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 0.0 0.1638 0.3222 -0.3222
A/J m 0.0 0.2316 0.4556 -0.4556
B6.A-Chr1 f 0.0 0.2316 0.4556 -0.4556
B6.A-Chr1 m 0.5 0.2316 0.9556 0.0444
B6.A-Chr10 f 0.5 0.2316 0.9556 0.0444
B6.A-Chr10 m 0.75 0.2316 1.2056 0.2944
B6.A-Chr11 f 0.375 0.2316 0.8306 -0.0806
B6.A-Chr11 m 0.5 0.2072 0.9075 0.0925
B6.A-Chr12 f 0.25 0.2316 0.7056 -0.2056
B6.A-Chr12 m 1.0 0.2316 1.4556 0.5444
B6.A-Chr13 f 0.0 0.293 0.5763 -0.5763
B6.A-Chr13 m 0.1429 0.2476 0.63 -0.3442
B6.A-Chr14 f 0.125 0.2316 0.5806 -0.3306
B6.A-Chr14 m 0.125 0.2316 0.5806 -0.3306
B6.A-Chr15 f 0.75 0.2316 1.2056 0.2944
B6.A-Chr15 m 0.125 0.2316 0.5806 -0.3306
B6.A-Chr16 f 0.125 0.2316 0.5806 -0.3306
B6.A-Chr16 m 0.875 0.2316 1.3306 0.4194
B6.A-Chr17 f 0.25 0.2316 0.7056 -0.2056
B6.A-Chr17 m 0.625 0.2316 1.0806 0.1694
B6.A-Chr18 f 0.25 0.2316 0.7056 -0.2056
B6.A-Chr18 m 1.125 0.2316 1.5806 0.6694
B6.A-Chr19 f 0.75 0.2316 1.2056 0.2944
B6.A-Chr19 m 0.125 0.2316 0.5806 -0.3306
B6.A-Chr2 f 0.375 0.2316 0.8306 -0.0806
B6.A-Chr2 m 0.625 0.2316 1.0806 0.1694
B6.A-Chr3 f 0.375 0.2316 0.8306 -0.0806
B6.A-Chr3 m 0.375 0.2316 0.8306 -0.0806
B6.A-Chr4 f 0.0 0.2476 0.4871 -0.4871
B6.A-Chr4 m 0.5 0.2316 0.9556 0.0444
B6.A-Chr5 f 0.375 0.2316 0.8306 -0.0806
B6.A-Chr5 m 0.5 0.2316 0.9556 0.0444
B6.A-Chr6 f 1.75 0.2316 2.2056 1.2944
B6.A-Chr6 m 0.5 0.2316 0.9556 0.0444
B6.A-Chr7 f 0.0 0.2316 0.4556 -0.4556
B6.A-Chr7 m 0.0 0.2316 0.4556 -0.4556
B6.A-Chr8 f 0.5 0.2316 0.9556 0.0444
B6.A-Chr8 m 1.5 0.2316 1.9556 1.0444
B6.A-Chr9 f 0.0 0.2316 0.4556 -0.4556
B6.A-Chr9 m 0.125 0.2316 0.5806 -0.3306
B6.A-ChrX f 0.0 0.2316 0.4556 -0.4556
B6.A-ChrX m 0.0 0.2316 0.4556 -0.4556
B6.A-ChrY f 0.0 0.2316 0.4556 -0.4556
B6.A-ChrY m 0.125 0.2316 0.5806 -0.3306
C57BL/6J f 0.0625 0.1638 0.3847 -0.2597
C57BL/6J m 0.0 0.2316 0.4556 -0.4556


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 0.0 0.1418 0.279 -0.279
B6.A-Chr1 both 0.25 0.1638 0.5722 -0.0722
B6.A-Chr10 both 0.625 0.1638 0.9472 0.3028
B6.A-Chr11 both 0.4375 0.1554 0.7432 0.1318
B6.A-Chr12 both 0.625 0.1638 0.9472 0.3028
B6.A-Chr13 both 0.0714 0.1918 0.4487 -0.3059
B6.A-Chr14 both 0.125 0.1638 0.4472 -0.1972
B6.A-Chr15 both 0.4375 0.1638 0.7597 0.1153
B6.A-Chr16 both 0.5 0.1638 0.8222 0.1778
B6.A-Chr17 both 0.4375 0.1638 0.7597 0.1153
B6.A-Chr18 both 0.6875 0.1638 1.0097 0.3653
B6.A-Chr19 both 0.4375 0.1638 0.7597 0.1153
B6.A-Chr2 both 0.5 0.1638 0.8222 0.1778
B6.A-Chr3 both 0.375 0.1638 0.6972 0.0528
B6.A-Chr4 both 0.25 0.1695 0.5835 -0.0835
B6.A-Chr5 both 0.4375 0.1638 0.7597 0.1153
B6.A-Chr6 both 1.125 0.1638 1.4472 0.8028
B6.A-Chr7 both 0.0 0.1638 0.3222 -0.3222
B6.A-Chr8 both 1.0 0.1638 1.3222 0.6778
B6.A-Chr9 both 0.0625 0.1638 0.3847 -0.2597
B6.A-ChrX both 0.0 0.1638 0.3222 -0.3222
B6.A-ChrY both 0.0625 0.1638 0.3847 -0.2597
C57BL/6J both 0.0313 0.1418 0.3103 -0.2478




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA