MPD: Data set: Lake3

Procedures conducted:

• rotarod		Latency to fall from fixed and accelerating rotorods, multiple trials.
• hole board test		Exploratory, locomotor, and anxiety-related behavior.
• grip strength		3 trials.

Lake3 downloads
• Download Lake3 project data set animal data, as uploaded
• Download Lake3 animal data matrix with factor-related expansion applied as necessary
• Download Lake3 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Lake3 measures:

MA:0000615 forelimb muscle
MP:0001362 abnormal anxiety-related response
MP:0001392 abnormal locomotor behavior
MP:0001440 abnormal grooming behavior
MP:0001504 abnormal posture
MP:0001515 abnormal grip strength
MP:0001516 abnormal motor coordination/balance
MP:0001761 abnormal urination pattern
MP:0013189 abnormal exploration in a new environment
MP:0020147 abnormal defecation amount
VT:0001392 locomotor behavior trait
VT:0001440 grooming behavior trait
VT:0001505 body posture trait
VT:0001516 motor coordination/balance trait
VT:0003620 urine output
VT:0004262 physical strength trait
VT:0010080 skeletal muscle physiology trait
VT:0010461 excretion behavior trait
VT:0010462 defecation behavior trait
VT:0010471 exploratory behavior trait
VT:0010716 anxiety-related behavior trait

Investigators	Jeffrey Lake The Jackson Laboratory, Bar Harbor, ME Leah Rae Donahue The Jackson Laboratory, Bar Harbor, ME Muriel T Davisson The Jackson Laboratory, Bar Harbor, ME
Contact	Jeffrey Lake jpl@jax.org
Part of a series:	• physiology see Lake1 • SHIRPA see Lake2 • behavior (this project) Lake3
Project type	Phenotype strain survey data set
MPD identifiers	Lake3 MPD:190
Data changelog	2 updates/corrections. Initial release date: 10/2007.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Lake3:1	Lake3	hole board test	(none)	number of stretch attends in 5 min test [n] stretch_attends 19001	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:2	Lake3	hole board test	(none)	number of grooming episodes in 5 min test [n] grooming 19002	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:3	Lake3	hole board test	(none)	number of fecal boli in 5 min test [n] defecation 19003	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:4	Lake3	hole board test	(none)	number of urine puddles in 5 min test [n] urination 19004	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:5	Lake3	hole board test	(none)	latency to visit perimeter, 5 min test [s] lat_perimeter 19005	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:6	Lake3	hole board test	(none)	number of arena entries in 5 min test [n] arena_entries 19006	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:7	Lake3	hole board test	(none)	number of head dunks in 5 min test [n] head_dunk 19007	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:8	Lake3	hole board test	(none)	number of hole visits in 5 min test [n] hole_visit 19008	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:9	Lake3	hole board test	(none)	number of rearings in the arena in 5 min test [n] rearing_arena 19009	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:10	Lake3	hole board test	(none)	number of rearings in the perimeter in 5 min test [n] rearing_perimeter 19010	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:11	Lake3	hole board test	(none)	number of line crossings in 5 min test [n] line_crossings 19011	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:12	Lake3	hole board test	(none)	total locomotor activity, line crosses plus rearings, 5 min test [n] tot_activity 19012	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:13	Lake3	grip strength	(none)	grip strength mean peak tension over 3 trials [g] mean_grip 19013	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:14	Lake3	grip strength	(none)	grip strength maximum peak tension over 3 trials [g] max_grip 19014	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:15	Lake3	rotarod	(none)	rotarod habituation, latency to fall from stationary rotarod [s] stationary 19015 trial1 trial2 trial3	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:18	Lake3	rotarod	(none)	latency to fall from 4 rpm rotarod [s] constant 19018 trial1 trial2 trial3	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3:21	Lake3	rotarod	(none)	latency to fall from accelerating rotarod, 60 rpm/min [s] accel 19021 trial1 trial2 trial3	B6.A consomic w/par	23	both	8-9wks	N=8

Lake3: Behavioral and neuromuscular phenotypes, C57BL/6J-Chr#A/J/NaJ mouse chromosome substitution panel (2005)

Lake3: Behavioral and neuromuscular phenotypes, C57BL/6J-Chr#^A/J/NaJ mouse chromosome substitution panel (2005)