Phenotype measure:   Lake2   irritability

ID, description, units MPD:21737   irritability   assessment of irritability during supine restraint (score 0-1)   [score]
Data set, strains Lake2   B6.A consomic w/par   23 strains     sex: both     age: 8wks
Procedure observation (SHIRPA)
Ontology mappings

  STRAIN COMPARISON PLOT
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Lake2 - assessment of irritability during supine restraint (score 0-1)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains23 strains
Mean of the strain means0.853   score 0.842   score
Median of the strain means1.00   score 1.00   score
SD of the strain means± 0.237 ± 0.302
Coefficient of variation (CV)0.278 0.359
Min–max range of strain means0.250   –   1.00   score 0   –   1.00   score
Mean sample size per strain8.3   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0976 0.0976 1.3074 0.2537
strain 22 22.9639 1.0438 13.9871 < 0.0001
sex:strain 22 6.5055 0.2957 3.9624 < 0.0001
Residuals 335 25.0 0.0746


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 0.25 0.447   16 0.112 1.79 -2.54
A/J m 0.0 0.0   8 0.0 0.0 -2.79
B6.A-Chr1 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr1 m 0.875 0.354   8 0.125 0.404 0.11
B6.A-Chr10 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr10 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr11 f 0.875 0.354   8 0.125 0.404 0.09
B6.A-Chr11 m 1.0 0.0   10 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr12 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr12 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr13 f 1.0 0.0   5 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr13 m 1.0 0.0   7 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr14 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr14 m 0.5 0.535   8 0.189 1.07 -1.13
B6.A-Chr15 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr15 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr16 f 0.75 0.463   8 0.164 0.617 -0.44
B6.A-Chr16 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr17 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr17 m 0.625 0.518   8 0.183 0.828 -0.72
B6.A-Chr18 f 0.625 0.518   8 0.183 0.828 -0.96
B6.A-Chr18 m 0.625 0.518   8 0.183 0.828 -0.72
B6.A-Chr19 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr19 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr2 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr2 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr3 f 0.5 0.535   8 0.189 1.07 -1.49
B6.A-Chr3 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr4 f 1.0 0.0   7 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr4 m 0.875 0.354   8 0.125 0.404 0.11
B6.A-Chr5 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr5 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr6 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr6 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr7 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr7 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr8 f 0.75 0.463   8 0.164 0.617 -0.44
B6.A-Chr8 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
B6.A-Chr9 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-Chr9 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
B6.A-ChrX f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.62
B6.A-ChrX m 0.875 0.354   8 0.125 0.404 0.11
B6.A-ChrY f 0.375 0.518   8 0.183 1.38 -2.02
B6.A-ChrY m 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.52
C57BL/6J f 0.5 0.516   16 0.129 1.03 -1.49
C57BL/6J m 0.0 0.0   8 0.0 0.0 -2.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 0.25 0.0683 0.3843 0.1157
A/J m 0.0 0.0966 0.19 -0.19
B6.A-Chr1 f 1.0 0.0966 1.19 0.81
B6.A-Chr1 m 0.875 0.0966 1.065 0.685
B6.A-Chr10 f 1.0 0.0966 1.19 0.81
B6.A-Chr10 m 1.0 0.0966 1.19 0.81
B6.A-Chr11 f 0.875 0.0966 1.065 0.685
B6.A-Chr11 m 1.0 0.0864 1.1699 0.8301
B6.A-Chr12 f 1.0 0.0966 1.19 0.81
B6.A-Chr12 m 1.0 0.0966 1.19 0.81
B6.A-Chr13 f 1.0 0.1222 1.2403 0.7597
B6.A-Chr13 m 1.0 0.1033 1.2031 0.7969
B6.A-Chr14 f 1.0 0.0966 1.19 0.81
B6.A-Chr14 m 0.5 0.0966 0.69 0.31
B6.A-Chr15 f 1.0 0.0966 1.19 0.81
B6.A-Chr15 m 1.0 0.0966 1.19 0.81
B6.A-Chr16 f 0.75 0.0966 0.94 0.56
B6.A-Chr16 m 1.0 0.0966 1.19 0.81
B6.A-Chr17 f 1.0 0.0966 1.19 0.81
B6.A-Chr17 m 0.625 0.0966 0.815 0.435
B6.A-Chr18 f 0.625 0.0966 0.815 0.435
B6.A-Chr18 m 0.625 0.0966 0.815 0.435
B6.A-Chr19 f 1.0 0.0966 1.19 0.81
B6.A-Chr19 m 1.0 0.0966 1.19 0.81
B6.A-Chr2 f 1.0 0.0966 1.19 0.81
B6.A-Chr2 m 1.0 0.0966 1.19 0.81
B6.A-Chr3 f 0.5 0.0966 0.69 0.31
B6.A-Chr3 m 1.0 0.0966 1.19 0.81
B6.A-Chr4 f 1.0 0.1033 1.2031 0.7969
B6.A-Chr4 m 0.875 0.0966 1.065 0.685
B6.A-Chr5 f 1.0 0.0966 1.19 0.81
B6.A-Chr5 m 1.0 0.0966 1.19 0.81
B6.A-Chr6 f 1.0 0.0966 1.19 0.81
B6.A-Chr6 m 1.0 0.0966 1.19 0.81
B6.A-Chr7 f 1.0 0.0966 1.19 0.81
B6.A-Chr7 m 1.0 0.0966 1.19 0.81
B6.A-Chr8 f 0.75 0.0966 0.94 0.56
B6.A-Chr8 m 1.0 0.0966 1.19 0.81
B6.A-Chr9 f 1.0 0.0966 1.19 0.81
B6.A-Chr9 m 1.0 0.0966 1.19 0.81
B6.A-ChrX f 1.0 0.0966 1.19 0.81
B6.A-ChrX m 0.875 0.0966 1.065 0.685
B6.A-ChrY f 0.375 0.0966 0.565 0.185
B6.A-ChrY m 1.0 0.0966 1.19 0.81
C57BL/6J f 0.5 0.0683 0.6343 0.3657
C57BL/6J m 0.0 0.0966 0.19 -0.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 0.125 0.0591 0.2413 0.0087
B6.A-Chr1 both 0.9375 0.0683 1.0718 0.8032
B6.A-Chr10 both 1.0 0.0683 1.1343 0.8657
B6.A-Chr11 both 0.9375 0.0648 1.0649 0.8101
B6.A-Chr12 both 1.0 0.0683 1.1343 0.8657
B6.A-Chr13 both 1.0 0.08 1.1573 0.8427
B6.A-Chr14 both 0.75 0.0683 0.8843 0.6157
B6.A-Chr15 both 1.0 0.0683 1.1343 0.8657
B6.A-Chr16 both 0.875 0.0683 1.0093 0.7407
B6.A-Chr17 both 0.8125 0.0683 0.9468 0.6782
B6.A-Chr18 both 0.625 0.0683 0.7593 0.4907
B6.A-Chr19 both 1.0 0.0683 1.1343 0.8657
B6.A-Chr2 both 1.0 0.0683 1.1343 0.8657
B6.A-Chr3 both 0.75 0.0683 0.8843 0.6157
B6.A-Chr4 both 0.9375 0.0707 1.0766 0.7984
B6.A-Chr5 both 1.0 0.0683 1.1343 0.8657
B6.A-Chr6 both 1.0 0.0683 1.1343 0.8657
B6.A-Chr7 both 1.0 0.0683 1.1343 0.8657
B6.A-Chr8 both 0.875 0.0683 1.0093 0.7407
B6.A-Chr9 both 1.0 0.0683 1.1343 0.8657
B6.A-ChrX both 0.9375 0.0683 1.0718 0.8032
B6.A-ChrY both 0.6875 0.0683 0.8218 0.5532
C57BL/6J both 0.25 0.0591 0.3663 0.1337




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA