MPD: Phenotype measures mapped to MA:0000368, kidney

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Ankra-Badu1:9	Ankra-Badu1	organ weights	(none)	right kidney weight [mg] KIDNEY 21209	QTL population		both	10wks	N=502	2009

Auwerx1:225	Auwerx1	organ weights	high-fat diet	kidney weight (both) [g] kidney_wt 111404 CD HFD	BXD w/par	57	m	29wks	N=4	2016

Auwerx2:131	Auwerx2	organ weights	(none)	kidney weight (both) [g] kidney_wt 114659 CD HFD	inbred w/CC8	9	both	21wks	N=4	2021

Brockmann1:10	Brockmann1	organ weights	(none)	weight of kidney [mg] Kidney 21310	QTL population		both	6wks	N=138	2009

Brockmann1:27	Brockmann1	organ weights	(none)	weight of kidney [mg] kidney 21507	QTL population		both	6wks	N=201	2009

Chesler2:64	Chesler2	organ weights	(none)	kidney (left) weight [g] kidneyL_wt 43496	CC diallel w/par	46	both	7-15wks	N=3	2011

Chesler3:93	Chesler3	organ dimensions	(none)	kidney length [cm] kidney_length 43593 left right	CC pre w/par	124	both	7-15wks	N=1	2011

Chesler3:95	Chesler3	organ dimensions	(none)	kidney volume [cm³] kidney_vol 43595	CC pre w/par	77	both	7-15wks	N=1	2011

Chesler3:96	Chesler3	organ weights	(none)	kidney weight [g] kidney_wt 43596 left right both	CC pre w/par	351	both	7-15wks	N=2	2011

Cheverud1:17	Cheverud1	organ weights	high-fat diet	kidney weight (both) as percentage of body weight [%] kidneywt_adj 17820 control diet high-fat diet	LGXSM w/par	17	both	20-30wks	N=8	2004

Cowell1:3	Cowell1	in vitro assay	Staphylococcus aureus	log₁₀ bacterial colony count from kidney 24h post-infection (CFU/g) [log(n/g)] kidney_CFU 49003	inbred	13	f	8wks	N=6	2012

Deschepper1:23	Deschepper1	organ weights	(none)	kidney weight [mg] kidney 10423 right left both	inbred	13	both	10wks	N=10	2004

Deschepper1:24	Deschepper1	organ weights	(none)	kidney weight, normalized to body weight [mg] kidney_adj 10424 right left both	inbred	13	both	10wks	N=10	2004

Feng1:3	Feng1	organ weights	(none)	left kidney weight [g] LKW 21603	QTL population		m	8wks	N=336	2009

Feng1:4	Feng1	organ weights	(none)	right kidney weight [g] RKW 21604	QTL population		m	8wks	N=336	2009

Graham1:68	Graham1	RNA expression profiling	West Nile virus	virus in kidney, fold change compared to matched control, post infection WNV_kidney 63368 day 2 day 4 day 7 day 12	CC RIX	5	m	8-10wks	N=1	2015

Graham1:79	Graham1	RNA expression profiling	West Nile virus	Ifnb1 gene expression in kidney, fold change compared to matched control, post infection Ifnb1_kidney 63379 day 2 day 4 day 7 day 12	CC RIX	5	m	8-10wks	N=1	2015

Graham1:90	Graham1	RNA expression profiling	West Nile virus	Ifit1 gene expression in kidney, fold change compared to matched control, post infection Ifit1_kidney 63390 day 2 day 4 day 7 day 12	CC RIX	5	m	8-10wks	N=1	2015

Gros1:1	Gros1	in vitro assay	Candida albicans	kidney fungal load 48h post-infection, colony-forming units (log₁₀ CFU per kidney) [log(n)] fungal_load 38501	inbred	23	f	8-12wks	N=9	2011

Gros1:2	Gros1	in vitro assay	Candida albicans	susceptibility to C. albicans based on fungal load (0=susceptible; 1=resistant) [designation] susceptibility 38502	inbred	23	f	8-12wks	N=9	2011

Guay-Woodford1:2	Guay-Woodford1	organ dimensions	(none)	length of kidney [mm] kidney_length 10702	QTL population		f	2wks	N=144	2000

Guay-Woodford1:3	Guay-Woodford1	organ dimensions	(none)	kidney length normalized to body length [ratio] K_CR 10703	QTL population		f	2wks	N=144	2000

Guay-Woodford1:4	Guay-Woodford1	histopathology	(none)	renal cystic disease severity [score] severity 10704	QTL population		f	2wks	N=144	2000

Gupta1:2	Gupta1	organ weights	(none)	kidney weight [g] kidney 39102 left right both	inbred	7	both	postnatal d1	N=9	2011

Gupta1:5	Gupta1	organ weights	(none)	percent kidney weight to body weight [%] pct_kidney 39105 left right both	inbred	7	both	postnatal d1	N=9	2011

Gupta1:9	Gupta1	organ dimensions	(none)	kidney planar surface area [mm²] area_kidney 39109 left right	inbred	8	both	postnatal d1	N=9	2011

Gupta1:12	Gupta1	organ dimensions	(none)	normalized kidney planar surface area [mm²/g] adj_area_kidney 39112 left right	inbred	7	both	postnatal d1	N=9	2011

Gupta2:2	Gupta2	organ weights	(none)	kidney weight [g] kidney 39202 left right both	BXH	10	both	postnatal d1	N=14	2011

Gupta2:5	Gupta2	organ weights	(none)	percent kidney weight to body weight [%] pct_kidney 39205 left right both	BXH	10	both	postnatal d1	N=14	2011

Gupta2:9	Gupta2	organ dimensions	(none)	kidney planar surface area [mm²] area_kidney 39209 left right	BXH	10	both	postnatal d1	N=14	2011

Gupta2:12	Gupta2	organ dimensions	(none)	normalized kidney planar surface area [mm²/g] adj_area_kidney 39212 left right	BXH	10	both	postnatal d1	N=14	2011

Harrill2:41	Harrill2	organ weights	DB289	kidney (left) weight [g] Lt_kidney 44141 control DB289	inbred	34	f	6-8wks	N=5	2012

Harrill2:44	Harrill2	organ weights	DB289	kidney (right) weight [g] Rt_kidney 44144 control DB289	inbred	34	f	6-8wks	N=5	2012

Harrill2:48	Harrill2	organ weights	DB289	kidney (both) weight [g] both_kidney 44148 control DB289	inbred	34	f	6-8wks	N=5	2012

Harrill2:51	Harrill2	organ weights	DB289	total kidney weight as percentage of body weight [%] pctKW_BW 44151 control DB289 difference	inbred	34	f	6-8wks	N=5	2012

Hillebrands1:1	Hillebrands1	histopathology	(none)	number of perivascular immune cell clusters per renal cross-section [n] clusternum 51101	inbred	23	both	90wks	N=7	2014

Hillebrands1:2	Hillebrands1	histopathology	(none)	relative size of perivascular immune cell clusters [%] clustersize 51102	inbred	20	both	90wks	N=7	2014

Jaxpheno2:30	Jaxpheno2	organ weights	(none)	kidney (left) weight [g] kidney_L 22730 age 8wks age 16wks	inbred	11	both		N=8	2006

Jaxpheno2:32	Jaxpheno2	organ weights	(none)	kidney (right) weight [g] kidney_R 22732 age 8wks age 16wks	inbred	11	both		N=8	2006

Jaxpheno2:34	Jaxpheno2	organ weights	(none)	kidney (left) weight, as percentage of body weight [%] pct_kidney_L 22734 age 8wks age 16wks	inbred	11	both		N=8	2006

Jaxpheno2:36	Jaxpheno2	organ weights	(none)	kidney (right) weight, as percentage of body weight [%] pct_kidney_R 22736 age 8wks age 16wks	inbred	11	both		N=8	2006

Korstanje2:1	Korstanje2	histopathology	(none)	percentage of glomeruli exhibiting mesangial matrix expansion [%] pct_MME 51001 6mo 12mo 20mo	inbred	29	m		N=6	2013

Mrug1:4	Mrug1	organ dimensions	(none)	kidney length [mm] Klength 17504	QTL population		both	10d	N=230	2005

Mrug1:5	Mrug1	organ dimensions	(none)	kidney length, square root [sqrt(mm)] sqrtKL 17505	QTL population		both	10d	N=230	2005

Mrug1:6	Mrug1	organ dimensions	(none)	crown to rump length of kidney [mm] CRLength 17506	QTL population		both	10d	N=230	2005

Mrug1:7	Mrug1	organ dimensions	(none)	kidney weight/crown to rump length KL-CRL-Ratio 17507	QTL population		both	10d	N=230	2005

Mrug1:8	Mrug1	organ dimensions	(none)	kidney weight/crown to rump length, log transformed logKL-CRL-Ratio 17508	QTL population		both	10d	N=230	2005

Mrug1:9	Mrug1	organ weights	(none)	kidney weight [g] KW 17509	QTL population		both	10d	N=230	2005

Mrug1:10	Mrug1	organ weights	(none)	kidney weight, square root [sqrt(g)] sqrtKW 17510	QTL population		both	10d	N=230	2005

Mrug1:12	Mrug1	organ weights	(none)	kidney weight/body weight KW-BW-Ratio 17512	QTL population		both	10d	N=230	2005

Mrug1:13	Mrug1	organ weights	(none)	kidney weight/body weight, log transformed logKW-BW-ratio 17513	QTL population		both	10d	N=230	2005

Mrug1:14	Mrug1	organ dimensions	(none)	kidney volume [ml] KVolume 17514	QTL population		both	10d	N=230	2005

Mrug1:15	Mrug1	organ dimensions	(none)	kidney volume, square root [sqrt(ml)] sqrtKV 17515	QTL population		both	10d	N=230	2005

Mrug1:16	Mrug1	organ dimensions	(none)	renal principal component of kidney length, weight and volume Prin1 17516	QTL population		both	10d	N=230	2005

Reed1:9	Reed1	organ weights	(none)	kidney weight [g] kidneys 32609 weight [g] as percent of body weight [%]	inbred	28	m	29-67wks	N=12	2009

Reed2:46	Reed2	organ weights	(none)	kidney weight (both) [g] kidney_wt 53146	B6.129 and 129.B6 consomic w/par	9	both	26wks	N=17	2015

Rusyn6:51	Rusyn6	organ weights	trichloroethylene	kidney weight as a percent of body weight [%] kidney_adj 51251 control TCE	inbred	7	m	6-7wks	N=4	2014

Rusyn6:54	Rusyn6	histopathology	trichloroethylene	BrdU-positive nuclei in kidney (proximal tubule cell proliferation), relative to control group [%] BrdU_kidney_tce 51254	inbred	7	m	6-7wks	N=3	2014

Rusyn6:55	Rusyn6	histopathology	trichloroethylene	kidney injury molecule 1 (KIM-1) positive proximal tubules [%] KIM1_kidney 51255 control TCE	inbred	7	m	6-7wks	N=4	2014

Rusyn6:58	Rusyn6	drug and metabolite quantification	trichloroethylene	trichloroacetic acid (kidney TCA) [nmol/g] TCA_kidney_tce 51258	inbred	7	m	6-7wks	N=4	2014

Rusyn6:60	Rusyn6	drug and metabolite quantification	trichloroethylene	dichloroacetic acid (kidney DCA) [nmol/g] DCA_kidney_tce 51260	inbred	6	m	6-7wks	N=3	2014

Rusyn6:62	Rusyn6	drug and metabolite quantification	trichloroethylene	trichloroethanol (kidney TCOH) [nmol/g] TCOH_kidney_tce 51262	inbred	7	m	6-7wks	N=4	2014

Rusyn6:64	Rusyn6	drug and metabolite quantification	trichloroethylene	S-(1,2-dichlorovinyl) glutathione (kidney DCVG) [pmol/g] DCVG_kidney_tce 51264	inbred	6	m	6-7wks	N=2	2014

Rusyn6:66	Rusyn6	drug and metabolite quantification	trichloroethylene	S-(1,2-dichlorovinyl)-L-cysteine (kidney DCVC) [pmol/g] DCVC_kidney_tce 51266	inbred	6	m	6-7wks	N=2	2014

Rusyn6:68	Rusyn6	RNA expression profiling	trichloroethylene	Acox1, mRNA in kidney, relative to control group [ratio] Acox1_kidney_tce 51268	inbred	7	m	6-7wks	N=3	2014

Rusyn6:70	Rusyn6	RNA expression profiling	trichloroethylene	Cyp4a10, mRNA in kidney, relative to control group [ratio] Cyp4a10_kidney_tce 51270	inbred	7	m	6-7wks	N=3	2014

Schoonjans1:224	Schoonjans1	organ weights	high-fat diet	kidney weight (both) [g] kidney_wt 112859 CD HFD	BXD w/par	36	m	29wks	N=5	2021

Shorter8:2	Shorter8	organ weights	(none)	kidney weight, right [g] kidney_wt 110157	DO population		m	12-15wks	N=147	2019

Ankra-Badu1

organ weights

(none)

right kidney weight [mg] KIDNEY 21209

QTL population

both

10wks

N=502

2009

Auwerx1

organ weights

high-fat diet

kidney weight (both) [g] kidney_wt 111404 CD HFD

BXD w/par

57

m

29wks

N=4

2016

Auwerx2

organ weights

(none)

kidney weight (both) [g] kidney_wt 114659 CD HFD

inbred w/CC8

9

both

21wks

N=4

2021

Brockmann1

organ weights

(none)

weight of kidney [mg] Kidney 21310

QTL population

both

6wks

N=138

2009

Brockmann1

organ weights

(none)

weight of kidney [mg] kidney 21507

QTL population

both

6wks

N=201

2009

Chesler2

organ weights

(none)

kidney (left) weight [g] kidneyL_wt 43496

CC diallel w/par

46

both

7-15wks

N=3

2011

Chesler3

organ dimensions

(none)

kidney length [cm] kidney_length 43593 left right

CC pre w/par

124

both

7-15wks

N=1

2011

Chesler3

organ dimensions

(none)

kidney volume [cm³] kidney_vol 43595

CC pre w/par

77

both

7-15wks

N=1

2011

Chesler3

organ weights

(none)

kidney weight [g] kidney_wt 43596 left right both

CC pre w/par

351

both

7-15wks

N=2

2011

Cheverud1

organ weights

high-fat diet

kidney weight (both) as percentage of body weight [%] kidneywt_adj 17820 control diet high-fat diet

LGXSM w/par

17

both

20-30wks

N=8

2004

Cowell1

in vitro assay

Staphylococcus aureus

log₁₀ bacterial colony count from kidney 24h post-infection (CFU/g) [log(n/g)] kidney_CFU 49003

inbred

13

f

8wks

N=6

2012

Deschepper1

organ weights

(none)

kidney weight [mg] kidney 10423 right left both

inbred

13

both

10wks

N=10

2004

Deschepper1

organ weights

(none)

kidney weight, normalized to body weight [mg] kidney_adj 10424 right left both

inbred

13

both

10wks

N=10

2004

Feng1

organ weights

(none)

left kidney weight [g] LKW 21603

QTL population

m

8wks

N=336

2009

Feng1

organ weights

(none)

right kidney weight [g] RKW 21604

QTL population

m

8wks

N=336

2009

Graham1

RNA expression profiling

West Nile virus

virus in kidney, fold change compared to matched control, post infection WNV_kidney 63368 day 2 day 4 day 7 day 12

CC RIX

5

m

8-10wks

N=1

2015

Graham1

RNA expression profiling

West Nile virus

Ifnb1 gene expression in kidney, fold change compared to matched control, post infection Ifnb1_kidney 63379 day 2 day 4 day 7 day 12

CC RIX

5

m

8-10wks

N=1

2015

Graham1

RNA expression profiling

West Nile virus

Ifit1 gene expression in kidney, fold change compared to matched control, post infection Ifit1_kidney 63390 day 2 day 4 day 7 day 12

CC RIX

5

m

8-10wks

N=1

2015

Gros1

in vitro assay

Candida albicans

kidney fungal load 48h post-infection, colony-forming units (log₁₀ CFU per kidney) [log(n)] fungal_load 38501

inbred

23

f

8-12wks

N=9

2011

Gros1

in vitro assay

Candida albicans

susceptibility to C. albicans based on fungal load (0=susceptible; 1=resistant) [designation] susceptibility 38502

inbred

23

f

8-12wks

N=9

2011

Guay-Woodford1

organ dimensions

(none)

length of kidney [mm] kidney_length 10702

QTL population

f

2wks

N=144

2000

Guay-Woodford1

organ dimensions

(none)

kidney length normalized to body length [ratio] K_CR 10703

QTL population

f

2wks

N=144

2000

Guay-Woodford1

histopathology

(none)

renal cystic disease severity [score] severity 10704

QTL population

f

2wks

N=144

2000

Gupta1

organ weights

(none)

kidney weight [g] kidney 39102 left right both

inbred

7

both

postnatal d1

N=9

2011

Gupta1

organ weights

(none)

percent kidney weight to body weight [%] pct_kidney 39105 left right both

inbred

7

both

postnatal d1

N=9

2011

Gupta1

organ dimensions

(none)

kidney planar surface area [mm²] area_kidney 39109 left right

inbred

8

both

postnatal d1

N=9

2011

Gupta1

organ dimensions

(none)

normalized kidney planar surface area [mm²/g] adj_area_kidney 39112 left right

inbred

7

both

postnatal d1

N=9

2011

Gupta2

organ weights

(none)

kidney weight [g] kidney 39202 left right both

BXH

10

both

postnatal d1

N=14

2011

Gupta2

organ weights

(none)

percent kidney weight to body weight [%] pct_kidney 39205 left right both

BXH

10

both

postnatal d1

N=14

2011

Gupta2

organ dimensions

(none)

kidney planar surface area [mm²] area_kidney 39209 left right

BXH

10

both

postnatal d1

N=14

2011

Gupta2

organ dimensions

(none)

normalized kidney planar surface area [mm²/g] adj_area_kidney 39212 left right

BXH

10

both

postnatal d1

N=14

2011

Harrill2

organ weights

DB289

kidney (left) weight [g] Lt_kidney 44141 control DB289

inbred

34

f

6-8wks

N=5

2012

Harrill2

organ weights

DB289

kidney (right) weight [g] Rt_kidney 44144 control DB289

inbred

34

f

6-8wks

N=5

2012

Harrill2

organ weights

DB289

kidney (both) weight [g] both_kidney 44148 control DB289

inbred

34

f

6-8wks

N=5

2012

Harrill2

organ weights

DB289

total kidney weight as percentage of body weight [%] pctKW_BW 44151 control DB289 difference

inbred

34

f

6-8wks

N=5

2012

Hillebrands1

histopathology

(none)

number of perivascular immune cell clusters per renal cross-section [n] clusternum 51101

inbred

23

both

90wks

N=7

2014

Hillebrands1

histopathology

(none)

relative size of perivascular immune cell clusters [%] clustersize 51102

inbred

20

both

90wks

N=7

2014

Jaxpheno2

organ weights

(none)

kidney (left) weight [g] kidney_L 22730 age 8wks age 16wks

inbred

11

both

N=8

2006

Jaxpheno2

organ weights

(none)

kidney (right) weight [g] kidney_R 22732 age 8wks age 16wks

inbred

11

both

N=8

2006

Jaxpheno2

organ weights

(none)

kidney (left) weight, as percentage of body weight [%] pct_kidney_L 22734 age 8wks age 16wks

inbred

11

both

N=8

2006

Jaxpheno2

organ weights

(none)

kidney (right) weight, as percentage of body weight [%] pct_kidney_R 22736 age 8wks age 16wks

inbred

11

both

N=8

2006

Korstanje2

histopathology

(none)

percentage of glomeruli exhibiting mesangial matrix expansion [%] pct_MME 51001 6mo 12mo 20mo

inbred

29

m

N=6

2013

Mrug1

organ dimensions

(none)

kidney length [mm] Klength 17504

QTL population

both

10d

N=230

2005

Mrug1

organ dimensions

(none)

kidney length, square root [sqrt(mm)] sqrtKL 17505

QTL population

both

10d

N=230

2005

Mrug1

organ dimensions

(none)

crown to rump length of kidney [mm] CRLength 17506

QTL population

both

10d

N=230

2005

Mrug1

organ dimensions

(none)

kidney weight/crown to rump length KL-CRL-Ratio 17507

QTL population

both

10d

N=230

2005

Mrug1

organ dimensions

(none)

kidney weight/crown to rump length, log transformed logKL-CRL-Ratio 17508

QTL population

both

10d

N=230

2005

Mrug1

organ weights

(none)

kidney weight [g] KW 17509

QTL population

both

10d

N=230

2005

Mrug1

organ weights

(none)

kidney weight, square root [sqrt(g)] sqrtKW 17510

QTL population

both

10d

N=230

2005

Mrug1

organ weights

(none)

kidney weight/body weight KW-BW-Ratio 17512

QTL population

both

10d

N=230

2005

Mrug1

organ weights

(none)

kidney weight/body weight, log transformed logKW-BW-ratio 17513

QTL population

both

10d

N=230

2005

Mrug1

organ dimensions

(none)

kidney volume [ml] KVolume 17514

QTL population

both

10d

N=230

2005

Mrug1

organ dimensions

(none)

kidney volume, square root [sqrt(ml)] sqrtKV 17515

QTL population

both

10d

N=230

2005

Mrug1

organ dimensions

(none)

renal principal component of kidney length, weight and volume Prin1 17516

QTL population

both

10d

N=230

2005

Reed1

organ weights

(none)

kidney weight [g] kidneys 32609 weight [g] as percent of body weight [%]

inbred

28

m

29-67wks

N=12

2009

Reed2

organ weights

(none)

kidney weight (both) [g] kidney_wt 53146

B6.129 and 129.B6 consomic w/par

9

both

26wks

N=17

2015

Rusyn6

organ weights

trichloroethylene

kidney weight as a percent of body weight [%] kidney_adj 51251 control TCE

inbred

7

m

6-7wks

N=4

2014

Rusyn6

histopathology

trichloroethylene

BrdU-positive nuclei in kidney (proximal tubule cell proliferation), relative to control group [%] BrdU_kidney_tce 51254

inbred

7

m

6-7wks

N=3

2014

Rusyn6

histopathology

trichloroethylene

kidney injury molecule 1 (KIM-1) positive proximal tubules [%] KIM1_kidney 51255 control TCE

inbred

7

m

6-7wks

N=4

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

trichloroacetic acid (kidney TCA) [nmol/g] TCA_kidney_tce 51258

inbred

7

m

6-7wks

N=4

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

dichloroacetic acid (kidney DCA) [nmol/g] DCA_kidney_tce 51260

inbred

6

m

6-7wks

N=3

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

trichloroethanol (kidney TCOH) [nmol/g] TCOH_kidney_tce 51262

inbred

7

m

6-7wks

N=4

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

S-(1,2-dichlorovinyl) glutathione (kidney DCVG) [pmol/g] DCVG_kidney_tce 51264

inbred

6

m

6-7wks

N=2

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

S-(1,2-dichlorovinyl)-L-cysteine (kidney DCVC) [pmol/g] DCVC_kidney_tce 51266

inbred

6

m

6-7wks

N=2

2014

Rusyn6

RNA expression profiling

trichloroethylene

Acox1, mRNA in kidney, relative to control group [ratio] Acox1_kidney_tce 51268

inbred

7

m

6-7wks

N=3

2014

Rusyn6

RNA expression profiling

trichloroethylene

Cyp4a10, mRNA in kidney, relative to control group [ratio] Cyp4a10_kidney_tce 51270

inbred

7

m

6-7wks

N=3

2014

Schoonjans1

organ weights

high-fat diet

kidney weight (both) [g] kidney_wt 112859 CD HFD

BXD w/par

36

m

29wks

N=5

2021

Shorter8

organ weights

(none)

kidney weight, right [g] kidney_wt 110157

DO population

m

12-15wks

N=147

2019

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