Project measure / variable:   Gros1   fungal_load

ID, description, units MPD:38501   fungal_load   kidney fungal load 48h post-infection, colony-forming units (log10 CFU per kidney)   [log(n)]  
Candida albicans study
Data set, strains Gros1   inbred   23 strains     sex: f     age: 8-12wks
Procedure in vitro assay
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  STRAIN COMPARISON PLOT
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Gros1 - kidney fungal load 48h post-infection, colony-forming units (log10 CFU per kidney)



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested23 strains
Mean of the strain means3.97   log(n)
Median of the strain means3.49   log(n)
SD of the strain means± 1.15
Coefficient of variation (CV)0.289
Min–max range of strain means2.33   –   6.04   log(n)
Mean sample size per strain9.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 265.6802 12.0764 37.8863 < 0.0001
Residuals 185 58.9694 0.3188


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.93 0.518   10 0.164 0.177 2.3, 3.64 -0.91
A/J f 6.04 0.127   9 0.0424 0.0211 5.83, 6.17 1.8
AKR/J f 3.88 0.353   13 0.0978 0.0909 3.11, 4.39 -0.08
BALB/cByJ f 3.21 0.635   8 0.225 0.198 2.0, 3.91 -0.67
BPL/1J f 2.33 0.472   8 0.167 0.202 2.0, 3.11 -1.43
BTBR T+ Itpr3tf/J f 5.64 0.257   10 0.0814 0.0456 5.05, 5.89 1.45
BUB/BnJ f 3.31 0.957   8 0.338 0.289 2.0, 4.39 -0.58
C3H/HeJ f 4.19 0.462   10 0.146 0.11 3.65, 4.97 0.19
C57BL/6J f 4.08 0.488   8 0.173 0.12 3.08, 4.56 0.09
C57BLKS/J f 3.35 0.346   8 0.122 0.103 2.9, 3.97 -0.54
CAST/EiJ f 2.61 0.642   10 0.203 0.246 2.0, 3.59 -1.19
CBA/J f 3.75 0.277   8 0.0981 0.0739 3.49, 4.31 -0.2
DBA/2J f 5.3 0.545   10 0.172 0.103 4.71, 6.07 1.16
DDY/JclSidSeyFrkJ f 3.38 0.779   8 0.276 0.23 2.0, 4.48 -0.52
FVB/NJ f 5.47 0.774   10 0.245 0.141 4.68, 6.41 1.3
KK/HlJ f 5.93 0.163   10 0.0516 0.0275 5.58, 6.13 1.7
MRL/MpJ f 2.98 0.812   8 0.287 0.273 2.0, 4.06 -0.87
MSM/MsJ f 2.87 0.569   8 0.201 0.199 2.0, 3.41 -0.96
NOD/ShiLtJ f 5.08 0.744   10 0.235 0.147 3.79, 6.12 0.96
NZW/LacJ f 3.41 0.555   10 0.175 0.163 2.48, 4.55 -0.49
PWD/PhJ f 2.95 0.602   9 0.201 0.204 2.0, 3.54 -0.89
SJL/J f 3.49 0.715   8 0.253 0.205 2.0, 4.09 -0.42
SM/J f 5.22 0.448   7 0.169 0.0859 4.47, 5.75 1.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.932 0.1785 3.2842 2.5798
A/J f 6.0389 0.1882 6.4102 5.6676
AKR/J f 3.8785 0.1566 4.1874 3.5695
BALB/cByJ f 3.2063 0.1996 3.6001 2.8124
BPL/1J f 2.3337 0.1996 2.7276 1.9399
BTBR T+ Itpr3tf/J f 5.644 0.1785 5.9962 5.2918
BUB/BnJ f 3.3088 0.1996 3.7026 2.9149
C3H/HeJ f 4.191 0.1785 4.5432 3.8388
C57BL/6J f 4.0825 0.1996 4.4763 3.6887
C57BLKS/J f 3.3463 0.1996 3.7401 2.9524
CAST/EiJ f 2.608 0.1785 2.9602 2.2558
CBA/J f 3.755 0.1996 4.1488 3.3612
DBA/2J f 5.298 0.1785 5.6502 4.9458
DDY/JclSidSeyFrkJ f 3.385 0.1996 3.7788 2.9912
FVB/NJ f 5.475 0.1785 5.8272 5.1228
KK/HlJ f 5.928 0.1785 6.2802 5.5758
MRL/MpJ f 2.975 0.1996 3.3688 2.5812
MSM/MsJ f 2.8675 0.1996 3.2613 2.4737
NOD/ShiLtJ f 5.076 0.1785 5.4282 4.7238
NZW/LacJ f 3.412 0.1785 3.7642 3.0598
PWD/PhJ f 2.9456 0.1882 3.3168 2.5743
SJL/J f 3.4938 0.1996 3.8876 3.0999
SM/J f 5.2171 0.2134 5.6381 4.7961




  GWAS USING LINEAR MIXED MODELS