Project measure / variable:   Rusyn6   BrdU_kidney_tce

ID, description, units MPD:51254   BrdU_kidney_tce   BrdU-positive nuclei in kidney (proximal tubule cell proliferation), relative to control group   [%]  
trichloroethylene study
Data set, strains Rusyn6   inbred   7 strains     sex: m     age: 6-7wks
Procedure histopathology
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  STRAIN COMPARISON PLOT
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Rusyn6 - BrdU-positive nuclei in kidney (proximal tubule cell proliferation), relative to control group



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means44.0   %
Median of the strain means48.6   %
SD of the strain means± 7.67
Coefficient of variation (CV)0.174
Min–max range of strain means33.8   –   51.7   %
Mean sample size per strain3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 1235.5571 205.9262 1.8445 0.1498
Residuals 17 1897.8892 111.6405


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 48.6 10.5   3 6.05 0.215 37.5, 58.3 0.6
A/J m 36.1 2.42   3 1.4 0.0672 33.3, 37.5 -1.03
BTBR T+ Itpr3tf/J m 49.8 17.8   4 8.9 0.357 37.5, 76.2 0.75
C57BL/6J m 51.7 6.98   3 4.03 0.135 44.4, 58.3 1.0
CAST/EiJ m 38.1 8.35   3 4.82 0.219 28.6, 44.4 -0.77
NOD/ShiLtJ m 33.8 7.81   4 3.91 0.231 23.1, 41.2 -1.33
NZW/LacJ m 50.1 9.92   4 4.96 0.198 41.2, 64.3 0.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 48.6 6.1003 61.4705 35.7295
A/J m 36.1 6.1003 48.9705 23.2295
BTBR T+ Itpr3tf/J m 49.825 5.283 60.9712 38.6788
C57BL/6J m 51.7 6.1003 64.5705 38.8295
CAST/EiJ m 38.0667 6.1003 50.9371 25.1962
NOD/ShiLtJ m 33.775 5.283 44.9212 22.6288
NZW/LacJ m 50.075 5.283 61.2212 38.9288




  GWAS USING LINEAR MIXED MODELS