Project measure / variable:   Rusyn6   DCA_kidney_tce

ID, description, units MPD:51260   DCA_kidney_tce   dichloroacetic acid (kidney DCA)   [nmol/g]  
trichloroethylene study
Data set, strains Rusyn6   inbred   6 strains     sex: m     age: 6-7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn6 - dichloroacetic acid (kidney DCA)

NOD/ShiLtJA/JC57BL/6J129S1/SvImJBTBR T<+> Itpr3<tf>/JNZW/LacJ nmol/g 0.51.01.52.02.53.03.54.04.5femalemale


  MEASURE SUMMARY
Measure Summary Male
Number of strains tested6 strains
Mean of the strain means0.891   nmol/g
Median of the strain means0.733   nmol/g
SD of the strain means± 0.497
Coefficient of variation (CV)0.557
Min–max range of strain means0.500   –   1.83   nmol/g
Mean sample size per strain2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 4.5242 1.131 1.2409 0.3495
Residuals 11 10.0258 0.9114


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Strain
Sex
Mean
SD
N mice
SEM
CV
Min, Max
Z score
129S1/SvImJ m 0.633 0.153   3 0.0882 0.241 0.5, 0.8 -0.52
A/J m 1.0 0.0   1   0.0 0.0 1.0, 1.0 0.22
BTBR T+ Itpr3tf/J m 0.55 0.0707   2   0.05 0.129 0.5, 0.6 -0.69
C57BL/6J m 0.833 0.153   3 0.0882 0.183 0.7, 1.0 -0.12
NOD/ShiLtJ m 1.83 1.81   4 0.907 0.994 0.7, 4.5 1.89
NZW/LacJ m 0.5 0.141   4 0.0707 0.283 0.4, 0.7 -0.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.6333 0.5512 1.8465 0.0
BTBR T+ Itpr3tf/J m 0.55 0.6751 2.0358 0.0
C57BL/6J m 0.8333 0.5512 2.0465 0.0
NOD/ShiLtJ m 1.825 0.4773 2.8756 0.7744
NZW/LacJ m 0.5 0.4773 1.5506 0.0




  GWAS USING LINEAR MIXED MODELS

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