Phenotype measure:   Rusyn6   Cyp4a10_kidney_tce

ID, description, units MPD:51270   Cyp4a10_kidney_tce   Cyp4a10, mRNA in kidney, relative to control group   [ratio]
trichloroethylene study
Data set, strains Rusyn6   inbred   7 strains     sex: m     age: 6-7wks
Procedure RNA expression profiling
Ontology mappings

  STRAIN COMPARISON PLOT
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Rusyn6 - Cyp4a10, mRNA in kidney, relative to control group



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means17.3   ratio
Median of the strain means2.77   ratio
SD of the strain means± 37.0
Coefficient of variation (CV)2.14
Min–max range of strain means1.67   –   101   ratio
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 24822.139 4137.0232 3.5881 0.0229
Residuals 14 16141.9933 1152.9995


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 2.07 0.0577   3 0.0333 0.0279 2.0, 2.1 -0.41
A/J m 4.4 3.32   3 1.92 0.754 1.3, 7.9 -0.35
BTBR T+ Itpr3tf/J m 1.67 0.569   3 0.328 0.341 1.2, 2.3 -0.42
C57BL/6J m 6.77 8.05   3 4.65 1.19 1.2, 16.0 -0.28
CAST/EiJ m 2.3 1.32   3 0.764 0.575 1.3, 3.8 -0.41
NOD/ShiLtJ m 101.0 89.4   3 51.6 0.881 7.6, 186.0 2.27
NZW/LacJ m 2.77 1.01   3 0.581 0.364 1.7, 3.7 -0.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 2.0667 19.6044 44.114 0.0
A/J m 4.4 19.6044 46.4473 0.0
BTBR T+ Itpr3tf/J m 1.6667 19.6044 43.714 0.0
C57BL/6J m 6.7667 19.6044 48.814 0.0
CAST/EiJ m 2.3 19.6044 44.3473 0.0
NOD/ShiLtJ m 101.4667 19.6044 143.514 59.4194
NZW/LacJ m 2.7667 19.6044 44.814 0.0




  GENOME-WIDE ASSOCIATION (GWAS) STATIC PLOT
Plot generated with EMMA / pyLMM using 132K SNP array. Click on plot to view at larger size.