Project measure / variable:   Rusyn6   DCVC_kidney_tce

ID, description, units MPD:51266   DCVC_kidney_tce   S-(1,2-dichlorovinyl)-L-cysteine (kidney DCVC)   [pmol/g]  
trichloroethylene study
Data set, strains Rusyn6   inbred   6 strains     sex: m     age: 6-7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn6 - S-(1,2-dichlorovinyl)-L-cysteine (kidney DCVC)



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested6 strains
Mean of the strain means31.0   pmol/g
Median of the strain means20.0   pmol/g
SD of the strain means± 25.9
Coefficient of variation (CV)0.834
Min–max range of strain means9.60   –   73.0   pmol/g
Mean sample size per strain2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 3 7386.8419 2462.2806 2.8629 0.0965
Residuals 9 7740.715 860.0794


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 16.6 4.79   4 2.39 0.288 12.0, 22.2 -0.56
BTBR T+ Itpr3tf/J m 9.6 0.52   3 0.3 0.0541 9.3, 10.2 -0.83
C57BL/6J m 73.0 57.6   2   40.8 0.79 32.2, 114.0 1.62
CAST/EiJ m 23.3 0.0   1   0.0 0.0 23.3, 23.3 -0.3
NOD/ShiLtJ m 52.5 38.1   4 19.0 0.726 12.8, 103.0 0.83
NZW/LacJ m 11.1 0.0   1   0.0 0.0 11.1, 11.1 -0.77


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 16.6 14.6636 49.7713 0.0
BTBR T+ Itpr3tf/J m 9.6 16.932 47.9029 0.0
C57BL/6J m 72.95 20.7374 119.8613 26.0387
NOD/ShiLtJ m 52.45 14.6636 85.6213 19.2787




  GWAS USING LINEAR MIXED MODELS