Study designs: all MPD measure sets of study design type basedoses

basedoses = repeated measures, baseline then treated multiple doses, same cohort

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg) Year
    Berndt1 34210 ventilator methacholine airway resistance (H2O pressure)   [cm/mL/s]     baseline    MCh challenge (mg/mL):    1    3    10    30 inbred 36 both 9-12wks N=9 2010
    Berndt1 34221 ventilator methacholine airway resistance (as % of baseline, H2O pressure)   [%]     MCh challenge (mg/mL):    1    3    10    30 inbred 36 both 9-12wks N=8 2010
    Berndt2 35101 plethysmography methacholine minute ventilation   [mL/min]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35108 plethysmography methacholine breath frequency   [n/min]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35114 plethysmography methacholine inspiratory phase   [s]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35121 plethysmography methacholine expiratory phase   [s]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35128 plethysmography methacholine respiratory cycle   [s]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35134 plethysmography methacholine duty cycle   [ratio]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35141 plethysmography methacholine inspiratory flow rate   [mL/kg/s]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35148 plethysmography methacholine expiratory flow rate   [mL/kg/s]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35154 plethysmography methacholine respiratory flow rate   [mL/kg/s]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35161 plethysmography methacholine enhanced pause     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35168 plethysmography methacholine tidal volume   [mL]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35181 ventilator methacholine airway resistance (H20 pressure)   [cm/mL/s]     saline    1 MCh    3 MCh    10 MCh    30 MCh    response index inbred 29 both 9-12wks N=9 2010
    Berndt2 35191 ventilator methacholine lung tissue dynamic elastance (H20 pressure)   [cm/mL]     saline    1 MCh    3 MCh    10 MCh    30 MCh    response index inbred 29 both 9-12wks N=9 2010
    Bodnar1 22601 intake monitoring sucrose daily chow intake with sucrose in drinking water   [g]     baseline    0.01%    2.5%    20% inbred 11 m 13-17wks N=10 2006
    Bodnar1 22605 intake monitoring sucrose daily sucrose intake with sucrose in drinking water   [mL]     baseline    0.01%    2.5%    20% inbred 12 m 13-17wks N=10 2006
    Bodnar1 22609 intake monitoring sucrose total daily caloric intake with sucrose in drinking water   [kcal]     baseline    0.01%    2.5%    20% inbred 11 m 13-17wks N=10 2006
    Bodnar1 22613 intake monitoring sucrose daily chow caloric intake with sucrose in drinking water   [kcal]     baseline    0.01%    2.5%    20% inbred 11 m 13-17wks N=10 2006
    Bodnar1 22617 intake monitoring sucrose daily sucrose caloric intake with sucrose in drinking water   [cal]     (baseline n/a)    0.01%    2.5%    20% inbred 12 m 13-17wks N=10 2006
    Bodnar1 22620 intake monitoring sucrose daily water intake with sucrose in drinking water   [mL]     baseline    0.01%    2.5%    20% inbred 12 m 13-17wks N=10 2006
    Bodnar1 22624 intake monitoring sucrose daily fluid (sucrose + water) intake with sucrose in drinking water   [mL]     baseline    0.01%    2.5%    20% inbred 12 m 13-17wks N=10 2006
    Bodnar1 22628 intake monitoring sucrose percent sucrose calories to daily total caloric intake with sucrose in drinking water   [%]     baseline    0.01%    2.5%    20% inbred 11 m 13-17wks N=10 2006
    Bodnar1 22632 intake monitoring sucrose percent sucrose intake with sucrose in drinking water   [%]     baseline    0.01%    2.5%    20% inbred 12 m 13-17wks N=10 2006
    Crabbe2 15504 monitoring system diazepam horizontal distance traveled (immediately to 15 min post-injection)   [cm]     baseline    doses mg/kg:    2    4    8    16 inbred 15 m 6-7wks N=8 1998
    Crabbe2 15509 monitoring system diazepam vertical (rearing) activity (immediately to 15 min post-injection)   [n]     baseline    doses mg/kg:    2    4    8    16 inbred 15 m 6-7wks N=8 1998
    Crabbe2 15514 body temperature diazepam body temperature (30 min post-injection)   [°C]     baseline    doses mg/kg:    2    4    8    16 inbred 15 m 6-7wks N=8 1998
    Jentsch2 49732 operant conditioning chamber cocaine horizontal beam breaks   [n]     baseline    5 mg/kg    10 mg/kg    20 mg/kg BXD 4 f 8-17wks N=13 2013
    Thomsen1 40701 open field test cocaine total activity, test 1   [n]     baseline    dose mg/kg i.p.:    3    10    18    32    56 inbred 15 both 8-10wks N=8 2011
    Thomsen1 40707 open field test cocaine total activity, test 2   [n]     baseline    dose mg/kg i.p.:    3    10    32 inbred 15 both 8-10wks N=8 2011
    Thomsen2 40801 open field test R-6-Br-APB total activity, dose response to D1 agonist   [n]     baseline    dose mg/kg i.p.    0.03    0.32    3.2    5.6 inbred 15 both 8-10wks N=8 2011
    Thomsen2 40806 open field test quinelorane total activity, dose response to D2 agonist   [n]     baseline    dose mg/kg i.p.    0.03    0.32    3.2    5.6 inbred 15 both 8-10wks N=8 2011
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