Thomsen2: Drug study: Psychomotor response to dopamine agonists in 15 mouse strains (2011)

Thomsen M, Ralph RJ, Caine SB. Psychomotor stimulation by dopamine D₁-like but not D₂-like agonists in most mouse strains. Exp Clin Psychopharmacol. 2011 Oct;19(5):342-60.   PubMed 21843011  

Thomsen2 downloads
• Download Thomsen2 project data set     animal data, as uploaded
• Download Thomsen2 animal data matrix     with factor-related expansion applied as necessary
• Download Thomsen2 strain means, SD, N, etc.     one row per strain/sex/measure
• Thomsen2 supplementary data
Investigators Morgane Thomsen       Harvard Medical School,  Boston, MA
S Barak Caine       Harvard Medical School,  Boston, MA
ContactMorgane Thomsen     Lab web site
Part of a series: • cocaine study   see Thomsen1
• dopamine agonists study   (this project) Thomsen2
AcknowledgementsFunding provided by NIH DA07252, DA12142
Project type Phenotype strain survey data set
MPD identifiersThomsen2     MPD:408
Data changelog No updates/corrections.       Initial release date: 06/2012.
Formatted citation
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Mice were evaluated for psychomotor effects of the dopamine D1-like agonist R-6-Br-APB and the dopamine D2-like agonist quinelorane, both at four different doses, using a locomotor activity procedure.

Procedures conducted:
• open field test  Locomotor activity. Baseline (saline) vs. dopamine agonists i.p. (several doses). 3h session.

Mice: inbred   15 strains   ♀♂   age 8-10wks   1 experimental group