Crabbe JC, Gallaher EJ, Cross SJ, Belknap JK. Genetic determinants of sensitivity to diazepam in inbred mice.
Behav Neurosci. 1998 Jun;112(3):668-77.
John C Crabbe Oregon Health & Science University, Portland, OR|
Edward J Gallaher Oregon Health & Science University, Portland, OR
John K Belknap Oregon Health & Science University, Portland, OR
With: Cross SJ
|Contact||John C Crabbe email@example.com|
|Acknowledgements||Funding provided by NIH DA05228, AA08621, AA10760; Department of Veterans Affairs
Acknowledgements: Jones G, Young E, Phillips E
|Phenotype strain survey data set|
|MPD identifiers||Crabbe2 MPD:155|
|No updates/corrections. Initial release date: 02/2009.|
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|Summary of procedures that were conducted|
|• rotarod||Latency to fall from 5 rpm rotarod immediately after diazepam injection.|
|• drug and metabolite quantification||Diazepam (and metabolite) concentration in brain tissue immediately after diazepam injection and rotarod.|
|• monitoring system||Locomotor activity. Baseline vs. immediately after Diazepam injection (several doses). 15 min test.|
|• body temperature||Baseline vs. 30 min after diazepam injection (several doses).|