Jentsch2: Drug study: Cocaine self-administration behavior and capacities for inhibitory control in 4 BXD recombinant inbred strains of mice (2013)

Cervantes MC, Laughlin RE, Jentsch JD. Cocaine self-administration behavior in inbred mouse lines segregating different capacities for inhibitory control. Psychopharmacology (Berl). 2013 Oct;229(3):515-25. doi: 10.1007/s00213-013-3135-4. Epub 2013 May 17.   PubMed 23681162     FullText

Jentsch2 downloads
• Download Jentsch2 project data set     one row per animal, one column per trait
• Download Jentsch2 strain means, SD, N, etc.     one row per strain/sex/measure
• Jentsch2 supplementary data
Participants J D Jentsch       Binghamton University,  Binghamton, NY
With: Cervantes MC, Laughlin RE
ContactJ D Jentsch     Lab web site
Part of a series: • reversal learning, 51 BXD strains   see Jentsch1
• cocaine study, 4 BXD strains   (this project) Jentsch2
AcknowledgementsFunding provided by NIH DA031852, DA024635, DE019580, MH083270, NS062410
Project type Phenotype strain survey data set
MPD identifiersJentsch2     MPD:497
Data changelog No updates/corrections.       Initial release date: 02/2014.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
"Self administration" = number of infusions earned during session
"Discrimination index" = index between active and inactive levers
"Time-out response" = number of responses made during post-infusion time-out periods
See protocol for additional clarification. Locomotor activity test involved baseline readings while other tests did not.

Summary of procedures that were conducted
• operant conditioning chamber Intravenous self-administration of cocaine via activation of levers, and locomotor activity.
Mice: BXD   4 strains   ♀♂   age 8-17wks   2 cohorts