Data set | Procedure | What's in this data set | Panel | Sex | Age (weeks) | Year |
---|---|---|---|---|---|---|
|
health assessment
with Plasmodium berghei |
Susceptibility, Plasmodium berghei (malaria). Parasitemia in blood and distribution in brain, spleen, lungs, liver. | inbred (31) | both | 8-12wks | 2010 |
|
study archive | Protein tau hyperphosphorylation. | QTL population | f | 3wks | 2003 |
|
RNA expression profiling
with Theiler's murine encephalomyelitis virus |
TMEV transcript abundance. | CC (5) | both | 4wks | 2017 |
|
organ dimensions | Eye diameter. | inbred (17) | both | 10-13wks | 2008 |
|
electroretinography | Photoreceptor measures: rod Awave, Bwave, cone Bwave. | inbred (17) | both | 10-13wks | 2008 |
|
slit lamp | Eye morphology. Frequency rates of disorders. | B6.PWD consomic w/par (28) | both | 44-61wks | 2012 |
|
ophthalmoscopy | Retinal spots, hypopigmentation. | B6.PWD consomic w/par (28) | both | 44-61wks | 2012 |
|
organ weights | Heart, brain, kidney, spleen, gonadal fat pads, testicle weights. | CC pre w/par (367) | both | 7-15wks | 2011 |
|
organ dimensions | Ear length (pinal). | F1 8way (63) | both | 7-8wks | 2004 |
|
drug and metabolite quantification
with diazepam |
Diazepam (and metabolite) concentration in brain tissue immediately after diazepam injection and rotarod. | inbred (15) | both | 6-7wks | 1998 |
|
organ weights | Brain weight. | BXD w/par (55) | both | 10-16wks | 2018 |
|
histopathology | Hippocampal histology. | BXD w/par (55) | both | 10-16wks | 2018 |
|
study archive | Exencephaly, neural tube defects in embryos. | QTL population | both | embryo | 2007 |
|
electroconvulsion test
with lamotrigine |
Electroconvulsive thresholds. Lamotrigine. 2 test sites. | inbred (16) | both | 6-11wks | 2000 |
|
observation (SHIRPA) | Behavior, and neurosensory responses (SHIRPA protocol). | inbred w/CC8 (8) | both | 8-10wks | 2020 |
|
organ dimensions | Axial length of eye. | inbred w/CC8 (8) | both | 14-17wks | 2020 |
|
Scheimpflug imaging | Eye lens density. | inbred w/CC8 (8) | both | 14-17wks | 2020 |
|
computed tomography | Retinal thickness and fundus vessels. | inbred w/CC8 (8) | both | 14-17wks | 2020 |
|
virtual optomotor | Threshold of spatial frequency. | inbred w/CC8 (8) | both | 14-17wks | 2020 |
|
drug and metabolite quantification
with lithium |
Lithium concentration in brain tissue and blood serum after lithium (several doses). | inbred (11) | m | 7-8wks | 2011 |
|
immune cell quantification
with West Nile virus |
T cell populations in brain and spleen. | CC RIX (5) | m | 8-10wks | 2015 |
|
RNA expression profiling
with West Nile virus |
Viral load and expression of Ifnb1 and Ifit1 in brain, kidney and spleen. | CC RIX (5) | m | 8-10wks | 2015 |
|
slit lamp | Eye morphology. Frequency rates of disorders. | inbred w/CC7 (41) | both | 6-7wks | 2008 |
|
ophthalmoscopy | Retinal fundoscopic examination. | inbred w/CC7 (41) | both | 6-7wks | 2008 |
|
observation (SHIRPA) | Behavior, and neurosensory responses (SHIRPA protocol). | KOMP | both | 8-18wks | 2021 |
|
ophthalmoscopy | Eye morphology. | KOMP | both | 8-18wks | 2021 |
|
slit lamp | Eye morphology. | KOMP | both | 8-18wks | 2021 |
|
electroretinography | Photoreceptor measures. | KOMP | both | 8-18wks | 2021 |
|
observation (SHIRPA) | Behavior, and neurosensory responses (SHIRPA protocol). | KOMP | both | 66-81wks | 2021 |
|
ophthalmoscopy | Eye morphology. | KOMP | both | 66-81wks | 2021 |
|
slit lamp | Eye morphology. | KOMP | both | 66-81wks | 2021 |
|
organ weights | Brain, heart, kidney, liver, spleen weights. | inbred (11) | both | 8, 16 wks | 2006 |
|
observation (SHIRPA) | Behavior, and neurosensory responses (SHIRPA protocol). | inbred (6) | m | 10wks | 2010 |
|
study archive | Ear microscopy (ampullae) and eye slit lamp study. | QTL population | f | 2007 | |
|
gait analysis | Angular velocity, Stride speed, Step length, Step width, and other gait metrics. | inbred w/CC8 (62) | both | 10-20 wks | 2021 |
|
observation (SHIRPA) | Behavior, and neurosensory responses (SHIRPA protocol). | B6.A consomic w/par (23) | both | 8wks | 2005 |
|
histopathology | Cerebral infarct volume, stroke susceptibility. Surgical occlusion of distal medial cerebral artery (MCA) to induce ischemia. | inbred (16) | both | 11-13wks | 2009 |
|
organ weights | Brain weight. | CC (52) | m | 7-20wks | 2018 |
|
protein activity assessment | Acetylcholinesterase activity of cerebellum and dorsal and ventral hippocampus | inbred (20) | m | 8-12wks | 2021 |
|
biomarker quantification | Temporal cortex amyloid level, age 6 and 14 mo. | F1 AD-BXD (55) | both | 7-65wks | 2019 |
|
histopathology | Cell proliferation in the rostral migratory stream. BrdU+ cells. | inbred (9) | both | 13-78wks | 2013 |
|
organ dimensions | Eye morphology. | inbred (4) | both | 13wks | 2006 |
|
organ weights | Brain, heart, kidney, liver, pancreas, spleen weights. | B6.129 and 129.B6 consomic w/par (9) | both | 26wks | 2015 |
|
microscopy
with exercise |
Examination of hippocampus dentate gyrus. Exercise wheel group vs. control group. | inbred (12) | both | 8-15wks | 2010 |
|
neurotransmitter quantification | Neurotransmitters. Molecular measures. | inbred (15) | m | 7-9wks | 2003 |
|
histopathology | Midsagittal area of corpus callosum. | BXD w/par (78) | both | various | 2012 |
|
RNA expression profiling | Hippocampal microRNA expression. Normalized data. | BXD w/par (26) | m | 15-16wks | 2012 |
|
health assessment
with pilocarpine |
Study of pilocarpine effect on epilepticus seizures. | inbred (11) | m | 8-10wks | 2012 |
|
study archive | Brain weight, body weight. | QTL population | both | 2005 | |
|
organ weights | Brain weight. | inbred (21) | both | 9, 12 wks | 2003 |
|
histopathology | Corpus callosum, hippocampus, anterior commisure. | inbred (21) | both | 9, 12 wks | 2003 |
|
biomarker quantification
with fluoxetine |
Brain tissue survey of 30 biochemical analytes. Fluoxetine-treated vs. control. 21d. | inbred (30) | m | 10-11wks | 2011 |