Hawes1: Morphological examination of the eye in 41 inbred strains of mice (2008)

Hawes NL, Chang B, Davisson MT   With: Hurd RE, Smith RS

       
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Participants Norm L Hawes       The Jackson Laboratory Bar Harbor, ME
Bo Chang       The Jackson Laboratory Bar Harbor, ME
Muriel T Davisson       The Jackson Laboratory Bar Harbor, ME
With: Hurd RE, Smith RS
ContactNorm L Hawes     nlh@jax.org     Lab web site
AcknowledgementsFunding provided by NIH EY07758; The Foundation Fighting Blindness

Generous funds from Hoffmann-LaRoche, Inc. were used to defray the cost of mice through the Mouse Phenome Project.
Project type Phenotype strain survey data set
MPD identifiersHawes1     MPD:267
Data changelog No updates/corrections.       Initial release date: 05/2008.
Formatted citation
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An investigation of eye phenotypes using slit-lamp and indirect ophthalmoscope. Data are expressed as frequency rates ranging from 0.0 to 1.0 (e.g., 1.0 indicates that all of the examined animals had the condition in at least one eye).

Summary of procedures that were conducted
• slit lamp Eye morphology. Frequency rates of disorders.
• ophthalmoscopy Retinal fundoscopic examination.
Mice: inbred w/CC7   41 strains   ♀♂   age 6-7wks   1 cohort

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Hawes1 26709 slit lamp (none) corneal opacity, focal   [frequency rate]  cornea_focal inbred w/CC7 41 both 6-7wks N=10
    Hawes1 26710 slit lamp (none) corneal opacity, diffuse   [frequency rate]  cornea_diffuse inbred w/CC7 41 both 6-7wks N=10
    Hawes1 26711 slit lamp (none) cornea-lens synechia   [frequency rate]  cornea_lens_adhesion inbred w/CC7 41 both 6-7wks N=10
    Hawes1 26712 slit lamp (none) iris coloboma   [frequency rate]  iris_coloboma inbred w/CC7 41 both 6-7wks N=10
    Hawes1 26713 slit lamp (none) iris transillumination defect   [frequency rate]  iris_trans_defect inbred w/CC7 41 both 6-7wks N=10
    Hawes1 26714 slit lamp (none) iris synechia   [frequency rate]  iris_adhesion inbred w/CC7 41 both 6-7wks N=10
    Hawes1 26715 slit lamp (none) nuclear cataract   [frequency rate]  cat_nuclear inbred w/CC7 40 both 6-7wks N=10
    Hawes1 26717 slit lamp (none) suture cataract   [frequency rate]  cat_suture inbred w/CC7 40 both 6-7wks N=10
    Hawes1 26718 slit lamp (none) punctate or snowflake cataract   [frequency rate]  cat_punctate inbred w/CC7 40 both 6-7wks N=10
    Hawes1 26719 ophthalmoscopy (none) retinal coloboma   [frequency rate]  ret_coloboma inbred w/CC7 40 both 6-7wks N=10
    Hawes1 26720 ophthalmoscopy (none) retinal hypopigmentation   [frequency rate]  ret_hypopig inbred w/CC7 40 both 6-7wks N=10
    Hawes1 26721 ophthalmoscopy (none) retinal degeneration   [frequency rate]  ret_degen inbred w/CC7 40 both 6-7wks N=10
    Hawes1 26722 ophthalmoscopy (none) optic cup, changes   [frequency rate]  optic_cup inbred w/CC7 40 both 6-7wks N=10
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