Intervention:   ethanol          

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg) Year
    Bennett3 37501 alcohol quantification ethanol blood ethanol concentration (BEC)   [mg/mL]     first loss of balance (ataxia)    first regain of balance    second regain of balance ILSXISS w/par 72 both 8-14wks N=5 2007
    Bennett3 37504 alcohol quantification ethanol acute functional tolerance to EtOH (AFT1 = BEC 2 minus BEC 1)   [mg/mL]  AFT1 ILSXISS w/par 72 both 8-14wks N=5 2007
    Bennett3 37505 alcohol quantification ethanol acute functional tolerance to EtOH (AFT2 = BEC 2 minus BEC 0)   [mg/mL]  AFT2 ILSXISS w/par 72 both 8-14wks N=5 2007
Chesler6 27104 rotarod ethanol rotarod: two trial post alcohol average minus pre trial latency to fall off rotarod (latency difference in seconds)   [second]  Rotarod_atax QTL population both 9-34wks N=187 2012
Chesler6 27105 body temperature ethanol post alcohol minus pre alcohol body temperature (degrees Celsius)   [° C]  Hypotherm QTL population both 9-34wks N=187 2012
Chesler6 27106 behavior observation ethanol alcohol induced Loss of Righting Reflex (latency to return of reflex in seconds)   [second]  LORR QTL population both 9-34wks N=187 2012
Chesler6 27107 alcohol quantification ethanol Blood Ethanol Concentration at return of righting reflex (latency to return in seconds)   [mg/mL]  LORR_BEC QTL population both 9-34wks N=187 2012
Chesler6 27109 rotarod ethanol rotarod: first alcohol trial performance (latency to fall in seconds)   [second]  RotaTest1 QTL population both 9-34wks N=187 2012
    Crabbe1 15403 balance beam ethanol missteps crossing 12.7mm wide balance beam   [n]     12.7mm beam:    control    i.p. doses g/kg:    1.0    1.2    1.4 inbred 7 both 8-16wks N=4 2003
    Crabbe1 15404 balance beam ethanol missteps crossing 15.8mm wide balance beam   [n]     15.8mm beam:    control    i.p. doses g/kg:    1.0    1.2    1.4 inbred 8 both 8-16wks N=5 2003
    Crabbe1 15405 balance beam ethanol missteps crossing 19.0 mm wide balance beam   [n]     19.0mm beam:    control    i.p. doses g/kg:    1.0    1.2    1.4 inbred 8 both 8-16wks N=4 2003
    Crabbe1 15406 grid test ethanol grid habituation, distance traveled   [cm]     control    i.p. doses g/kg:    1.5    2.0    2.5 inbred 8 both 8-16wks N=5 2003
    Crabbe1 15407 grid test ethanol grid habituation, missteps per cm   [n/cm]     control    i.p. doses g/kg:    1.5    2.0    2.5 inbred 8 both 8-16wks N=5 2003
    Crabbe3 15810 rotarod ethanol fixed speed 3 rpm rotarod (latency to fall)   [s]     ethanol i.p. g/kg:    1    2    3 inbred 9 both 9-17wks N=4 2003
    Crabbe3 15815 rotarod ethanol fixed speed 6 rpm rotarod (latency to fall)   [s]     ethanol i.p. g/kg:    1    2    3 inbred 9 both 9-17wks N=4 2003
    Crabbe3 15820 rotarod ethanol fixed speed 10 rpm rotarod (latency to fall)   [s]     ethanol i.p. g/kg:    1    2    3 inbred 7 both 9-17wks N=3 2003
    Crabbe3 15840 rotarod ethanol accelerating rotarod (latency to fall), test day 1 20 rpm/min (ARR1)   [s]     baseline    ethanol    Δchange (ethanol effect) inbred 8 both 9-17wks N=6 2003
    Crabbe3 15845 rotarod ethanol accelerating rotarod (latency to fall), test day 2 30 rpm/min (ARR1)   [s]     baseline    ethanol    Δchange (ethanol effect) inbred 8 both 9-17wks N=5 2003
    Crabbe3 15855 rotarod ethanol accelerating rotarod (latency to fall), test 20 rpm/min (ARR2)   [s]     baseline    ethanol inbred 21 both 9-17wks N=9 2003
    Crabbe3 15857 rotarod ethanol accelerating rotarod (ARR2) average latency of post-injection trials minus pre-injection trials (ETPOST - ETBASE) (20 rpm/min)   [s]  ARR2_chg_20rpm inbred 21 both 9-17wks N=9 2003
    Crabbe4 19101 vertical wire mesh ethanol latency to fall from a vertical wire mesh grid 30 min post-injection   [s]  latency_screen30 inbred 8 both 9-10wks N=5 2003
    Crabbe4 19102 dowel balance test ethanol latency to fall 0 min post-injection   [s]     9.5mm    15.8mm inbred 8 both 12-16wks N=4 2003
    Crabbe4 19103 dowel balance test ethanol latency to fall, 30 min post-injection   [s]     9.5mm    15.8mm inbred 8 both 12-16wks N=4 2003
    Crabbe4 19106 grip strength ethanol grip strength test: peak force applied   [g]     baseline    30min after ethanol inbred 21 both 7-12wks N=6 2003
    Crabbe4 19108 grip strength ethanol change in peak force applied (T0-T30) post-injection, grip strength test   [g]  gripEtOHeffect inbred 21 both 7-12wks N=6 2003
    Crabbe4 19109 grip strength ethanol percent change in average latency to fall post-injection, grip strength test   [%]  pct_gripchange inbred 21 both 7-12wks N=6 2003
    Crabbe4 19111 alcohol quantification ethanol blood ethanol concentration (BEC), 35 min post-injection, dowel (15.8 mm) test   [mg/mL]  BEC_dowel15_8 inbred 8 both 12-16wks N=3 2003
    Crabbe4 19112 alcohol quantification ethanol blood ethanol concentration   [mg/mL]     time after ethanol:    30min    60min    105min    150min inbred 21 both 7-12wks N=6 2003
    Crabbe5 19601 parallel rod floor test ethanol distance traveled, 1.6mm rod, 6mm space   [cm]     day1 control    day2 control    day3 ethanol inbred 8 both 8-10wks N=6 2005
    Crabbe5 19603 parallel rod floor test ethanol motor incoordination (errors/distance traveled) 1.6mm rod, 6mm space   [n/cm]     day1 control    day2 control    day3 ethanol inbred 8 both 7-14wks N=6 2005
    Metten1 16501 open field test ethanol line crossings, 2.75 g/kg i.p.   [n]     pre-injection    10min after injection    30min after inbred 9 both 8-11wks N=4 2004
    Metten1 16502 open field test ethanol line crossings, 3.0 g/kg i.p.   [n]     pre-injection    10min after injection    30min after inbred 9 both 8-11wks N=4 2004
    Metten1 16509 behavior observation ethanol hindlimb splay, 2.75 g/kg i.p.   [score]     10min after injection    30min after inbred 9 both 8-11wks N=4 2004
    Metten1 16511 behavior observation ethanol hindlimb splay, 3.0 g/kg i.p.   [score]     10min after injection    30min after inbred 9 both 8-11wks N=4 2004
    Metten1 16513 behavior observation ethanol erratic gait, 2.75 g/kg i.p.   [score]     10min after injection    30min after inbred 9 both 8-11wks N=4 2004
    Metten1 16515 behavior observation ethanol erratic gait, 3.0 g/kg i.p.   [score]     10min after injection    30min after inbred 9 both 8-11wks N=4 2004
    Metten2 19503 behavior observation ethanol peak handling-induced convulsion (HIC) score   [score]     control    ethanol    ethanol normalized to controls inbred 15 m 8-15wks N=10 2005
    Metten2 19506 behavior observation ethanol latency to first handling-induced convulsions score used to calculate peak ethanol   [h]  peak_latency inbred 15 m 8-15wks N=11 2005
    Metten2 19507 behavior observation ethanol withdrawal severity during 0-25h (area under curve of handling-induced convulsions scores)   [AUC]  withdrawal_EtOH inbred 15 m 8-15wks N=20 2005
    Metten2 19508 behavior observation ethanol withdrawal severity during 0-25h (area under curve of handling-induced convulsions scores), normalized to controls   [AUC]  withdrawal_EtOHadj inbred 15 m 8-15wks N=11 2005
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