Bennett3: Drug study: Acute functional tolerance to ethanol in 74 ILSXISS recombinant inbred strains of mice (2007)

Bennett B, Downing C, Carosone-Link P, Ponicsan H, Ruf C, Johnson TE. Quantitative trait locus mapping for acute functional tolerance to ethanol in the L x S recombinant inbred panel. Alcohol Clin Exp Res. 2007 Feb;31(2):200-8.   PubMed 17250610  

Bennett3 downloads
• Download Bennett3 project data set     animal data, as uploaded
• Download Bennett3 animal data matrix     with factor-related expansion applied as necessary
• Download Bennett3 strain means, SD, N, etc.     one row per strain/sex/measure
Investigators Beth Bennett       University of Colorado Denver School of Medicine,  Aurora, CO
Thomas E Johnson       University of Colorado,  Boulder, CO
Participants Downing C, Carosone-Link P, Ponicsan H, Ruf C
ContactBeth Bennett     Lab web site
AcknowledgementsFunding provided by NIH AA11984, AA08940
Project type Phenotype strain survey data set
MPD identifiersBennett3     MPD:375
Data changelog No updates/corrections.       Initial release date: 07/2011.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Alcohol sensitivity and acute alcohol tolerance were studied in a single cohort of mice using a test of ataxia: loss and regain of balance on a stationary wooden dowel upon exposure to two doses of EtOH within the same testing session.

Procedures conducted:
• alcohol quantification  Blood alcohol concentrations after ethanol injection over time, acute functional ethanol tolerance.

Mice: ILSXISS w/par   74 strains   ♀♂   age 8-14wks   1 experimental group