Crabbe5: Drug study: Assessment of ethanol sensitivity and intoxication using the parallel rod floor apparatus in 8 inbred strains of mice (2005)

Kamens HM, Phillips TJ, Holstein SE, Crabbe JC. Characterization of the parallel rod floor apparatus to test motor incoordination in mice. Genes Brain Behav. 2005 Jun;4(4):253-66.   PubMed 15924557  


       
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Participants John C Crabbe       Oregon Health & Science University Portland, OR
With: Kamens HM, Phillips TJ, Holstein SE
ContactJohn C Crabbe     crabbe@ohsu.edu
AcknowledgementsFunding provided by NIH AA10760, AA12714, AA07468; Department of Veterans Affairs.

Acknowledgements: Schlumbohm JP, Metten P, Mc Kinnon C.
Project type Phenotype strain survey data set
MPD identifiersCrabbe5     MPD:196
Data changelog No updates/corrections.       Initial release date: 12/2006.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
An investigation of the effects of alcohol by measuring locomotor activity and motor incoordination before and after administration of ethanol.

Summary of procedures that were conducted
• parallel rod floor test Parallel rod balance test, baseline vs. ethanol 2 g/kg i.p..
Mice: inbred   8 strains   ♀♂   age 7-14wks   2 cohorts

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Crabbe5 19601 parallel rod floor test ethanol distance traveled, 1.6mm rod, 6mm space   [cm]     day1 control    day2 control    day3 ethanol inbred 8 both 8-10wks N=6
    Crabbe5 19603 parallel rod floor test ethanol motor incoordination (errors/distance traveled) 1.6mm rod, 6mm space   [n/cm]     day1 control    day2 control    day3 ethanol inbred 8 both 7-14wks N=6
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