Phenotype measure:   Crabbe4   pct_gripchange

ID, description, units MPD:19109   pct_gripchange   percent change in average latency to fall post-injection, grip strength test   [%]
ethanol study
Data set, strains Crabbe4   inbred   21 strains     sex: both     age: 7-12wks
Procedure grip strength
Ontology mappings

  STRAIN COMPARISON PLOT
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Crabbe4 - percent change in average latency to fall post-injection, grip strength test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means34.0   % 43.1   %
Median of the strain means32.4   % 39.4   %
SD of the strain means± 14.1 ± 13.3
Coefficient of variation (CV)0.413 0.307
Min–max range of strain means14.2   –   60.5   % 24.3   –   69.9   %
Mean sample size per strain6.2   mice 5.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4268.8685 4268.8685 10.4557 0.0014
strain 19 31519.7809 1658.9358 4.0632 < 0.0001
sex:strain 19 6091.6334 320.6123 0.7853 0.723
Residuals 196 80023.484 408.2831


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 33.6 7.45   6 3.04 0.222 23.7, 44.7 -0.03
129S1/SvImJ m 61.4 13.8   6 5.62 0.224 45.8, 87.1 1.38
A/J f 27.3 11.7   6 4.76 0.427 17.3, 48.5 -0.48
A/J m 29.5 11.3   6 4.61 0.383 18.0, 46.6 -1.03
AKR/J f 32.8 9.68   6 3.95 0.295 20.5, 47.4 -0.09
AKR/J m 47.5 13.2   6 5.41 0.279 23.2, 62.2 0.33
BALB/cByJ f 44.8 16.2   6 6.61 0.361 29.3, 71.4 0.77
BALB/cByJ m 47.1 11.5   6 4.71 0.245 38.3, 65.0 0.3
BTBR T+ Itpr3tf/J f 51.5 27.0   2   19.1 0.524 32.4, 70.6 1.24
BTBR T+ Itpr3tf/J m 40.4 19.2   5 8.6 0.476 15.0, 56.8 -0.21
C3H/HeJ f 20.2 31.3   3 18.1 1.55 -15.2, 44.1 -0.98
C3H/HeJ m 33.8 20.2   6 8.23 0.597 10.1, 55.3 -0.71
C57BL/6J f 37.2 12.0   12 3.47 0.323 17.4, 63.6 0.23
C57BL/6J m 39.4 13.2   6 5.39 0.335 16.1, 50.2 -0.28
C57L/J f 22.1 11.0   6 4.47 0.495 5.7, 36.5 -0.85
C57L/J m 45.2 22.4   6 9.16 0.496 5.7, 64.8 0.15
C58/J f 19.9 9.23   4 4.62 0.465 11.3, 32.9 -1.0
C58/J m 27.8 12.9   4 6.43 0.463 9.6, 38.5 -1.16
CAST/EiJ f 29.7 16.5   6 6.73 0.556 5.8, 53.2 -0.31
CAST/EiJ m 24.3 16.2   5 7.23 0.666 -0.4, 40.1 -1.42
DBA/2J f 32.4 13.3   12 3.84 0.411 19.7, 55.1 -0.12
DBA/2J m 43.1 8.38   6 3.42 0.194 32.2, 54.4 0.0
FVB/NJ f 28.9 36.4   6 14.9 1.26 -17.0, 94.7 -0.36
FVB/NJ m 39.1 12.4   6 5.05 0.316 20.5, 57.1 -0.31
MOLF/EiJ f 56.5 27.9   7 10.5 0.494 30.2, 111.0 1.6
MOLF/EiJ m 55.0 46.4   6 19.0 0.844 -36.1, 88.2 0.89
NOD/ShiLtJ f 45.5 26.2   6 10.7 0.576 15.5, 88.8 0.82
NOD/ShiLtJ m 32.5 25.4   6 10.4 0.78 -0.5, 61.3 -0.8
NZB/BlNJ f 60.5 11.4   6 4.65 0.189 39.4, 73.5 1.88
NZB/BlNJ m 69.9 14.5   5 6.49 0.208 55.2, 86.9 2.02
PERA/EiJ f 16.6 8.15   8 2.88 0.49 6.6, 28.9 -1.24
PERA/EiJ m 35.5 23.7   4 11.9 0.668 14.5, 66.7 -0.58
PL/J f 39.8 9.66   6 3.95 0.243 24.2, 49.9 0.41
PL/J m 69.5 0.0   1   0.0 0.0 69.5, 69.5 1.99
SJL/J f 14.2 16.3   6 6.65 1.15 -12.5, 35.4 -1.41
SJL/J m 35.1 19.3   5 8.65 0.551 11.5, 64.1 -0.61
SM/J f 57.2 5.3   6 2.16 0.0927 47.4, 62.8 1.65
SM/J m 60.2 12.0   6 4.88 0.198 46.4, 75.1 1.29
SPRET/EiJ f 21.6 34.5   6 14.1 1.6 -23.8, 62.8 -0.88
SPRET/EiJ m 38.6 60.4   4 30.2 1.56 -51.3, 78.9 -0.34
SWR/J f 22.2 14.0   6 5.72 0.631 5.3, 39.2 -0.84
SWR/J m 31.2 21.1   6 8.6 0.675 9.3, 63.2 -0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 33.6 8.2491 49.8683 17.3317
129S1/SvImJ m 61.3833 8.2491 77.6517 45.115
A/J f 27.2833 8.2491 43.5517 11.015
A/J m 29.4833 8.2491 45.7517 13.215
AKR/J f 32.8333 8.2491 49.1017 16.565
AKR/J m 47.4833 8.2491 63.7517 31.215
BALB/cByJ f 44.85 8.2491 61.1183 28.5817
BALB/cByJ m 47.1 8.2491 63.3683 30.8317
BTBR T+ Itpr3tf/J f 51.5 14.2878 79.6776 23.3224
BTBR T+ Itpr3tf/J m 40.4 9.0364 58.2211 22.5789
C3H/HeJ f 20.2 11.6659 43.2069 0.0
C3H/HeJ m 33.7667 8.2491 50.035 17.4983
C57BL/6J f 37.1833 5.833 48.6868 25.6799
C57BL/6J m 39.4 8.2491 55.6683 23.1317
C57L/J f 22.1167 8.2491 38.385 5.8483
C57L/J m 45.2 8.2491 61.4683 28.9317
C58/J f 19.875 10.103 39.7996 0.0
C58/J m 27.75 10.103 47.6746 7.8254
CAST/EiJ f 29.6667 8.2491 45.935 13.3983
CAST/EiJ m 24.3 9.0364 42.1211 6.4789
DBA/2J f 32.35 5.833 43.8534 20.8466
DBA/2J m 43.1 8.2491 59.3683 26.8317
FVB/NJ f 28.8667 8.2491 45.135 12.5983
FVB/NJ m 39.0667 8.2491 55.335 22.7983
MOLF/EiJ f 56.4857 7.6372 71.5473 41.4242
MOLF/EiJ m 55.0333 8.2491 71.3017 38.765
NOD/ShiLtJ f 45.5 8.2491 61.7683 29.2317
NOD/ShiLtJ m 32.5333 8.2491 48.8017 16.265
NZB/BlNJ f 60.4667 8.2491 76.735 44.1983
NZB/BlNJ m 69.94 9.0364 87.7611 52.1189
PERA/EiJ f 16.6375 7.1439 30.7263 2.5487
PERA/EiJ m 35.5 10.103 55.4246 15.5754
SJL/J f 14.1667 8.2491 30.435 0.0
SJL/J m 35.12 9.0364 52.9411 17.2989
SM/J f 57.1833 8.2491 73.4517 40.915
SM/J m 60.25 8.2491 76.5183 43.9817
SPRET/EiJ f 21.5833 8.2491 37.8517 5.315
SPRET/EiJ m 38.625 10.103 58.5496 18.7004
SWR/J f 22.2167 8.2491 38.485 5.9483
SWR/J m 31.2167 8.2491 47.485 14.9483


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 47.4917 5.833 58.9951 35.9882
A/J both 28.3833 5.833 39.8868 16.8799
AKR/J both 40.1583 5.833 51.6618 28.6549
BALB/cByJ both 45.975 5.833 57.4784 34.4716
BTBR T+ Itpr3tf/J both 45.95 8.4528 62.6201 29.2799
C3H/HeJ both 26.9833 7.1439 41.0721 12.8945
C57BL/6J both 38.2917 5.0515 48.2539 28.3294
C57L/J both 33.6583 5.833 45.1618 22.1549
C58/J both 23.8125 7.1439 37.9013 9.7237
CAST/EiJ both 26.9833 6.1177 39.0483 14.9184
DBA/2J both 37.725 5.0515 47.6873 27.7627
FVB/NJ both 33.9667 5.833 45.4701 22.4632
MOLF/EiJ both 55.7595 5.6208 66.8445 44.6745
NOD/ShiLtJ both 39.0167 5.833 50.5201 27.5132
NZB/BlNJ both 65.2033 6.1177 77.2683 53.1384
PERA/EiJ both 26.0688 6.1868 38.27 13.8675
SJL/J both 24.6433 6.1177 36.7083 12.5784
SM/J both 58.7167 5.833 70.2201 47.2132
SPRET/EiJ both 30.1042 6.5215 42.9654 17.2429
SWR/J both 26.7167 5.833 38.2201 15.2132




  GWAS USING LINEAR MIXED MODELS