Project measure / variable:   Finn1   3pct_EtOH

ID, description, units MPD:25601   3pct_EtOH   dose of ethanol voluntarily consumed at 3% ethanol in water   [g/kg]  
ethanol study
Data set, strains Finn1   inbred   22 strains     sex: both     age: 8-9wks
Procedure bottle choice test
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  STRAIN COMPARISON PLOT
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Finn1 - dose of ethanol voluntarily consumed at 3% ethanol in water



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains22 strains
Mean of the strain means2.42   g/kg 1.59   g/kg
Median of the strain means1.81   g/kg 1.27   g/kg
SD of the strain means± 1.77 ± 1.00
Coefficient of variation (CV)0.728 0.629
Min–max range of strain means0.381   –   5.77   g/kg 0.244   –   3.60   g/kg
Mean sample size per strain7.5   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 51.6345 51.6345 30.944 < 0.0001
strain 21 546.2625 26.0125 15.589 < 0.0001
sex:strain 21 81.1593 3.8647 2.3161 0.0011
Residuals 293 488.9125 1.6686


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.15 2.59   8 0.916 1.21 0.22, 7.78 -0.16
129S1/SvImJ m 1.34 1.17   8 0.415 0.879 0.1, 2.89 -0.25
A/J f 0.89 1.25   8 0.442 1.41 0.21, 3.95 -0.87
A/J m 1.06 1.37   8 0.483 1.29 0.27, 3.63 -0.53
BALB/cByJ f 0.448 0.507   8 0.179 1.13 0.11, 1.65 -1.12
BALB/cByJ m 0.659 0.742   8 0.262 1.13 0.17, 2.28 -0.93
BTBR T+ Itpr3tf/J f 1.27 1.07   8 0.38 0.845 0.26, 3.07 -0.65
BTBR T+ Itpr3tf/J m 0.244 0.153   8 0.0542 0.629 0.07, 0.58 -1.35
BUB/BnJ f 1.45 1.8   3 1.04 1.24 0.17, 3.51 -0.55
BUB/BnJ m 1.05 1.31   7 0.496 1.25 0.26, 3.75 -0.54
C57BL/6J f 5.07 1.49   8 0.527 0.294 2.82, 6.97 1.5
C57BL/6J m 3.6 2.21   8 0.782 0.614 0.91, 6.42 2.0
C57BLKS/J f 3.89 0.84   8 0.297 0.216 2.66, 5.06 0.83
C57BLKS/J m 3.23 1.66   7 0.628 0.515 1.32, 6.02 1.63
C58/J f 4.66 1.68   8 0.595 0.361 3.15, 8.27 1.27
C58/J m 3.49 2.55   8 0.903 0.733 0.19, 7.76 1.89
CZECHII/EiJ f 5.77 1.93   4 0.965 0.335 4.0, 8.37 1.9
CZECHII/EiJ m 2.1 1.4   6 0.573 0.667 0.38, 3.9 0.51
DBA/2J f 0.381 0.203   8 0.0717 0.532 0.14, 0.76 -1.16
DBA/2J m 0.731 1.16   8 0.409 1.58 0.1, 3.55 -0.86
FVB/NJ f 0.542 0.494   8 0.175 0.911 0.11, 1.66 -1.07
FVB/NJ m 0.741 0.902   8 0.319 1.22 0.18, 2.28 -0.85
I/LnJ f 1.48 1.05   8 0.373 0.711 0.59, 3.78 -0.53
I/LnJ m 1.13 0.752   8 0.266 0.664 0.29, 2.53 -0.46
LP/J f 1.37 1.04   8 0.368 0.763 0.35, 3.01 -0.6
LP/J m 0.781 0.812   8 0.287 1.04 0.24, 2.37 -0.81
MA/MyJ f 4.12 2.32   8 0.822 0.564 0.35, 7.48 0.96
MA/MyJ m 1.64 2.03   8 0.718 1.23 0.26, 5.03 0.05
NOD/ShiLtJ f 4.64 0.509   8 0.18 0.11 4.0, 5.52 1.26
NOD/ShiLtJ m 2.83 0.842   8 0.298 0.298 1.59, 4.44 1.23
NON/ShiLtJ f 0.486 0.269   8 0.0951 0.553 0.18, 1.02 -1.1
NON/ShiLtJ m 0.299 0.21   8 0.0742 0.702 -1.29
NZB/BlNJ f 2.66 0.724   8 0.256 0.272 1.39, 3.58 0.13
NZB/BlNJ m 2.33 0.919   8 0.325 0.394 0.35, 3.23 0.74
NZW/LacJ f 0.943 0.611   6 0.249 0.648 0.26, 1.75 -0.84
NZW/LacJ m 0.944 0.54   10 0.171 0.572 0.25, 1.84 -0.65
PERA/EiJ f 4.0 1.65   5 0.738 0.413 2.14, 5.96 0.89
PERA/EiJ m 1.99 1.01   9 0.337 0.508 1.03, 4.41 0.4
RIIIS/J f 3.14 1.19   8 0.422 0.381 1.42, 4.9 0.41
RIIIS/J m 2.19 0.885   8 0.313 0.404 0.83, 3.16 0.6
SEA/GnJ f 0.463 0.307   8 0.109 0.664 0.1, 1.07 -1.11
SEA/GnJ m 1.2 1.23   8 0.435 1.03 0.22, 3.17 -0.39
SM/J f 3.5 1.93   8 0.684 0.553 0.46, 6.46 0.61
SM/J m 1.47 1.62   8 0.573 1.11 0.4, 4.14 -0.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.145 0.4567 3.0438 1.2462
129S1/SvImJ m 1.3363 0.4567 2.2351 0.4374
A/J f 0.89 0.4567 1.7888 0.0
A/J m 1.0625 0.4567 1.9613 0.1637
BALB/cByJ f 0.4475 0.4567 1.3463 0.0
BALB/cByJ m 0.6587 0.4567 1.5576 0.0
BTBR T+ Itpr3tf/J f 1.2713 0.4567 2.1701 0.3724
BTBR T+ Itpr3tf/J m 0.2438 0.4567 1.1426 0.0
BUB/BnJ f 1.45 0.7458 2.9178 0.0
BUB/BnJ m 1.0543 0.4882 2.0152 0.0934
C57BL/6J f 5.0675 0.4567 5.9663 4.1687
C57BL/6J m 3.6013 0.4567 4.5001 2.7024
C57BLKS/J f 3.8913 0.4567 4.7901 2.9924
C57BLKS/J m 3.2286 0.4882 4.1895 2.2677
C58/J f 4.6562 0.4567 5.5551 3.7574
C58/J m 3.4875 0.4567 4.3863 2.5887
CZECHII/EiJ f 5.7675 0.6459 7.0387 4.4963
CZECHII/EiJ m 2.1033 0.5274 3.1412 1.0654
DBA/2J f 0.3813 0.4567 1.2801 0.0
DBA/2J m 0.7312 0.4567 1.6301 0.0
FVB/NJ f 0.5425 0.4567 1.4413 0.0
FVB/NJ m 0.7412 0.4567 1.6401 0.0
I/LnJ f 1.4825 0.4567 2.3813 0.5837
I/LnJ m 1.1313 0.4567 2.0301 0.2324
LP/J f 1.3662 0.4567 2.2651 0.4674
LP/J m 0.7813 0.4567 1.6801 0.0
MA/MyJ f 4.1238 0.4567 5.0226 3.2249
MA/MyJ m 1.6438 0.4567 2.5426 0.7449
NOD/ShiLtJ f 4.6362 0.4567 5.5351 3.7374
NOD/ShiLtJ m 2.8275 0.4567 3.7263 1.9287
NON/ShiLtJ f 0.4863 0.4567 1.3851 0.0
NON/ShiLtJ m 0.2988 0.4567 1.1976 0.0
NZB/BlNJ f 2.6625 0.4567 3.5613 1.7637
NZB/BlNJ m 2.3338 0.4567 3.2326 1.4349
NZW/LacJ f 0.9433 0.5274 1.9812 0.0
NZW/LacJ m 0.944 0.4085 1.7479 0.1401
PERA/EiJ f 3.998 0.5777 5.135 2.861
PERA/EiJ m 1.9889 0.4306 2.8363 1.1415
RIIIS/J f 3.1363 0.4567 4.0351 2.2374
RIIIS/J m 2.1887 0.4567 3.0876 1.2899
SEA/GnJ f 0.4625 0.4567 1.3613 0.0
SEA/GnJ m 1.1988 0.4567 2.0976 0.2999
SM/J f 3.4963 0.4567 4.3951 2.5974
SM/J m 1.4663 0.4567 2.3651 0.5674


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.7406 0.3229 2.3762 1.105
A/J both 0.9763 0.3229 1.6118 0.3407
BALB/cByJ both 0.5531 0.3229 1.1887 0.0
BTBR T+ Itpr3tf/J both 0.7575 0.3229 1.3931 0.1219
BUB/BnJ both 1.2521 0.4457 2.1293 0.375
C57BL/6J both 4.3344 0.3229 4.97 3.6988
C57BLKS/J both 3.5599 0.3343 4.2178 2.902
C58/J both 4.0719 0.3229 4.7075 3.4363
CZECHII/EiJ both 3.9354 0.4169 4.7559 3.1149
DBA/2J both 0.5563 0.3229 1.1918 0.0
FVB/NJ both 0.6419 0.3229 1.2775 0.0063
I/LnJ both 1.3069 0.3229 1.9425 0.6713
LP/J both 1.0737 0.3229 1.7093 0.4382
MA/MyJ both 2.8838 0.3229 3.5193 2.2482
NOD/ShiLtJ both 3.7319 0.3229 4.3675 3.0963
NON/ShiLtJ both 0.3925 0.3229 1.0281 0.0
NZB/BlNJ both 2.4981 0.3229 3.1337 1.8625
NZW/LacJ both 0.9437 0.3335 1.6001 0.2872
PERA/EiJ both 2.9934 0.3603 3.7025 2.2844
RIIIS/J both 2.6625 0.3229 3.2981 2.0269
SEA/GnJ both 0.8306 0.3229 1.4662 0.195
SM/J both 2.4813 0.3229 3.1168 1.8457




  GWAS USING LINEAR MIXED MODELS