Phenotype measure:   Finn1   3pct_EtOHsach

ID, description, units MPD:25605   3pct_EtOHsach   dose of ethanol voluntarily consumed at 3% ethanol in water with 0.2% saccharin   [g/kg]
Data set, strains Finn1   inbred   22 strains     sex: both     age: 11-12wks
Procedure bottle choice test
Ontology mappings


  STRAIN COMPARISON PLOT
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Finn1 - dose of ethanol voluntarily consumed at 3% ethanol in water with 0.2% saccharin



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains22 strains
Mean of the strain means6.94   g/kg 4.66   g/kg
Median of the strain means6.75   g/kg 5.17   g/kg
SD of the strain means± 4.06 ± 3.01
Coefficient of variation (CV)0.585 0.646
Min–max range of strain means0.197   –   12.0   g/kg 0.436   –   9.37   g/kg
Mean sample size per strain7.5   mice 7.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 496.1409 496.1409 74.2785 < 0.0001
strain 21 3613.2608 172.06 25.7595 < 0.0001
sex:strain 21 291.0924 13.8615 2.0752 0.0043
Residuals 289 1930.3662 6.6795


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3.71 1.37   8 0.486 0.37 1.1, 5.51 -0.8
129S1/SvImJ m 1.17 0.665   8 0.235 0.569 0.09, 2.35 -1.16
A/J f 0.895 0.936   8 0.331 1.05 0.0, 2.45 -1.49
A/J m 1.43 1.76   8 0.621 1.23 0.0, 4.6 -1.07
BALB/cByJ f 6.34 1.77   8 0.627 0.28 3.12, 9.18 -0.15
BALB/cByJ m 4.88 0.401   7 0.151 0.0821 4.37, 5.39 0.07
BTBR T+ Itpr3tf/J f 1.4 0.981   8 0.347 0.699 0.08, 3.53 -1.36
BTBR T+ Itpr3tf/J m 1.05 0.917   8 0.324 0.875 0.15, 2.31 -1.2
BUB/BnJ f 0.197 0.174   3 0.1 0.884 0.0, 0.33 -1.66
BUB/BnJ m 0.436 0.616   7 0.233 1.41 0.0, 1.68 -1.4
C57BL/6J f 11.3 2.5   8 0.882 0.221 6.8, 14.0 1.07
C57BL/6J m 9.37 1.35   8 0.477 0.144 6.74, 10.6 1.56
C57BLKS/J f 11.4 1.88   8 0.664 0.165 8.72, 14.3 1.1
C57BLKS/J m 8.6 1.67   7 0.629 0.194 6.5, 11.4 1.31
C58/J f 12.0 4.35   8 1.54 0.363 5.56, 17.1 1.25
C58/J m 7.95 3.56   7 1.35 0.448 3.45, 12.6 1.09
CZECHII/EiJ f 6.78 7.39   4 3.7 1.09 0.4, 14.0 -0.04
CZECHII/EiJ m 0.6 0.663   6 0.271 1.11 0.0, 1.59 -1.35
DBA/2J f 1.32 1.04   7 0.394 0.787 0.45, 3.45 -1.38
DBA/2J m 0.745 0.769   8 0.272 1.03 0.1, 2.55 -1.3
FVB/NJ f 9.59 4.87   8 1.72 0.508 0.46, 14.1 0.65
FVB/NJ m 6.68 2.19   8 0.773 0.327 2.38, 9.85 0.67
I/LnJ f 11.6 2.57   8 0.91 0.222 7.13, 14.7 1.15
I/LnJ m 7.75 3.92   8 1.39 0.505 3.48, 14.8 1.03
LP/J f 2.4 1.95   8 0.689 0.812 0.23, 5.72 -1.12
LP/J m 2.9 2.55   8 0.903 0.881 0.74, 7.44 -0.58
MA/MyJ f 11.0 2.13   8 0.755 0.194 7.96, 14.6 1.0
MA/MyJ m 6.04 2.95   8 1.04 0.488 2.67, 11.7 0.46
NOD/ShiLtJ f 10.1 5.6   8 1.98 0.556 0.73, 17.0 0.78
NOD/ShiLtJ m 6.87 1.81   8 0.641 0.264 5.1, 10.2 0.73
NON/ShiLtJ f 6.71 3.12   7 1.18 0.466 1.6, 11.0 -0.06
NON/ShiLtJ m 1.76 1.19   8 0.422 0.677 0.3, 3.64 -0.96
NZB/BlNJ f 10.1 1.53   8 0.542 0.152 8.62, 13.4 0.78
NZB/BlNJ m 7.98 1.69   8 0.599 0.212 5.86, 9.98 1.1
NZW/LacJ f 5.31 1.97   6 0.805 0.371 1.95, 7.1 -0.4
NZW/LacJ m 3.72 2.33   10 0.737 0.627 0.6, 9.35 -0.31
PERA/EiJ f 10.6 1.72   5 0.771 0.163 9.53, 13.6 0.9
PERA/EiJ m 7.33 1.66   9 0.552 0.226 5.84, 10.3 0.89
RIIIS/J f 4.83 0.956   8 0.338 0.198 2.63, 5.63 -0.52
RIIIS/J m 3.36 1.48   8 0.524 0.442 0.76, 5.04 -0.43
SEA/GnJ f 4.41 4.48   8 1.58 1.02 0.36, 13.6 -0.62
SEA/GnJ m 5.45 3.11   8 1.1 0.571 1.28, 8.69 0.26
SM/J f 10.7 1.84   8 0.649 0.172 8.61, 12.7 0.93
SM/J m 6.43 4.52   8 1.6 0.703 1.27, 12.1 0.59


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3.7125 0.9137 5.5109 1.9141
129S1/SvImJ m 1.1688 0.9137 2.9672 0.0
A/J f 0.895 0.9137 2.6934 0.0
A/J m 1.4275 0.9137 3.2259 0.0
BALB/cByJ f 6.3375 0.9137 8.1359 4.5391
BALB/cByJ m 4.8829 0.9768 6.8055 2.9602
BTBR T+ Itpr3tf/J f 1.4038 0.9137 3.2022 0.0
BTBR T+ Itpr3tf/J m 1.0488 0.9137 2.8472 0.0
BUB/BnJ f 0.1967 1.4921 3.1335 0.0
BUB/BnJ m 0.4357 0.9768 2.3583 0.0
C57BL/6J f 11.2713 0.9137 13.0697 9.4728
C57BL/6J m 9.365 0.9137 11.1634 7.5666
C57BLKS/J f 11.375 0.9137 13.1734 9.5766
C57BLKS/J m 8.6029 0.9768 10.5255 6.6802
C58/J f 11.965 0.9137 13.7634 10.1666
C58/J m 7.9457 0.9768 9.8683 6.0231
CZECHII/EiJ f 6.7775 1.2922 9.3209 4.2341
CZECHII/EiJ m 0.6 1.0551 2.6767 0.0
DBA/2J f 1.3229 0.9768 3.2455 0.0
DBA/2J m 0.745 0.9137 2.5434 0.0
FVB/NJ f 9.5875 0.9137 11.3859 7.7891
FVB/NJ m 6.685 0.9137 8.4834 4.8866
I/LnJ f 11.5912 0.9137 13.3897 9.7928
I/LnJ m 7.7525 0.9137 9.5509 5.9541
LP/J f 2.3975 0.9137 4.1959 0.5991
LP/J m 2.9 0.9137 4.6984 1.1016
MA/MyJ f 11.0325 0.9137 12.8309 9.2341
MA/MyJ m 6.0438 0.9137 7.8422 4.2453
NOD/ShiLtJ f 10.07 0.9137 11.8684 8.2716
NOD/ShiLtJ m 6.8675 0.9137 8.6659 5.0691
NON/ShiLtJ f 6.7071 0.9768 8.6298 4.7845
NON/ShiLtJ m 1.7625 0.9137 3.5609 0.0
NZB/BlNJ f 10.075 0.9137 11.8734 8.2766
NZB/BlNJ m 7.9775 0.9137 9.7759 6.1791
NZW/LacJ f 5.31 1.0551 7.3867 3.2333
NZW/LacJ m 3.72 0.8173 5.3286 2.1114
PERA/EiJ f 10.562 1.1558 12.8369 8.2871
PERA/EiJ m 7.3289 0.8615 9.0245 5.6333
RIIIS/J f 4.8262 0.9137 6.6247 3.0278
RIIIS/J m 3.3562 0.9137 5.1547 1.5578
SEA/GnJ f 4.41 0.9137 6.2084 2.6116
SEA/GnJ m 5.4525 0.9137 7.2509 3.6541
SM/J f 10.68 0.9137 12.4784 8.8816
SM/J m 6.4338 0.9137 8.2322 4.6353


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.4406 0.6461 3.7123 1.1689
A/J both 1.1613 0.6461 2.4329 0.0
BALB/cByJ both 5.6102 0.6688 6.9265 4.2939
BTBR T+ Itpr3tf/J both 1.2263 0.6461 2.4979 0.0
BUB/BnJ both 0.3162 0.8917 2.0713 0.0
C57BL/6J both 10.3181 0.6461 11.5898 9.0464
C57BLKS/J both 9.9889 0.6688 11.3053 8.6726
C58/J both 9.9554 0.6688 11.2717 8.639
CZECHII/EiJ both 3.6888 0.8341 5.3305 2.047
DBA/2J both 1.0339 0.6688 2.3503 0.0
FVB/NJ both 8.1362 0.6461 9.4079 6.8646
I/LnJ both 9.6719 0.6461 10.9436 8.4002
LP/J both 2.6487 0.6461 3.9204 1.3771
MA/MyJ both 8.5381 0.6461 9.8098 7.2664
NOD/ShiLtJ both 8.4687 0.6461 9.7404 7.1971
NON/ShiLtJ both 4.2348 0.6688 5.5511 2.9185
NZB/BlNJ both 9.0262 0.6461 10.2979 7.7546
NZW/LacJ both 4.515 0.6673 5.8284 3.2016
PERA/EiJ both 8.9454 0.7208 10.3641 7.5268
RIIIS/J both 4.0912 0.6461 5.3629 2.8196
SEA/GnJ both 4.9313 0.6461 6.2029 3.6596
SM/J both 8.5569 0.6461 9.8286 7.2852




  GENOME-WIDE ASSOCIATION (GWAS) STATIC PLOT
Plot generated with EMMA / pyLMM using 132K SNP array. Click on plot to view at larger size.