Crabbe3: Drug study: Evaluation of ethanol intoxication using the rotarod in 22 inbred strains of mice (2003)

Rustay NR, Wahlsten D, Crabbe JC. Assessment of genetic susceptibility to ethanol intoxication in mice. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2917-22. Epub 2003 Feb 12.   PubMed 12584362  

Crabbe3 downloads
• Download Crabbe3 project data set     animal data, as uploaded
• Download Crabbe3 animal data matrix     with factor-related expansion applied as necessary
• Download Crabbe3 strain means, SD, N, etc.     one row per strain/sex/measure
• Crabbe3 supplementary data
Investigators John C Crabbe       Oregon Health & Science University,  Portland, OR
Douglas Wahlsten       University of Windsor,  Windsor, Ontario CANADA
Participants Rustay NR
ContactJohn C Crabbe
AcknowledgementsGenerous funds from AstraZeneca were used to defray the cost of mice through the Mouse Phenome Project Collaborations Program.
Project type Phenotype strain survey data set
MPD identifiersCrabbe3     MPD:158
Data changelog No updates/corrections.       Initial release date: 02/2010.
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Animals were evaluated on an accelerating and fixed speed rotarod following ethanol administration. This project has a complex study design involving multiple cohorts, as described in the protocol workflow table.

Procedures conducted:
• body weight 
• rotarod  Baseline and ethanol i.p. 3 fixed speeds (several doses) and accelerating.

Mice: inbred   22 strains   ♀♂   age 9-17wks   9 experimental groups