Crabbe3: Drug study: Evaluation of ethanol intoxication using the rotarod in 22 inbred strains of mice (2003)

Rustay NR, Wahlsten D, Crabbe JC. Assessment of genetic susceptibility to ethanol intoxication in mice. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2917-22. Epub 2003 Feb 12.   PubMed 12584362  


       
Crabbe3 downloads
• Download Crabbe3 project data set     one row per animal, one column per trait
• Download Crabbe3 strain means, SD, N, etc.     one row per strain/sex/measure
• Crabbe3 supplementary data
Participants John C Crabbe       Oregon Health & Science University Portland, OR
Douglas Wahlsten       University of Windsor Windsor, Ontario CANADA
With: Rustay NR
ContactJohn C Crabbe     crabbe@ohsu.edu
AcknowledgementsGenerous funds from AstraZeneca were used to defray the cost of mice through the Mouse Phenome Project Collaborations Program.
Project type Phenotype strain survey data set
MPD identifiersCrabbe3     MPD:158
Data changelog No updates/corrections.       Initial release date: 02/2010.
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Animals were evaluated on an accelerating and fixed speed rotarod following ethanol administration. This project has a complex study design involving multiple cohorts, as described in the protocol workflow table.

Summary of procedures that were conducted
• body weight
• rotarod Baseline and ethanol i.p. 3 fixed speeds (several doses) and accelerating.
Mice: inbred   22 strains   ♀♂   age 9-17wks   9 cohorts