Project measure / variable:   Finn1   10pct_EtOH

ID, description, units MPD:25603   10pct_EtOH   dose of ethanol voluntarily consumed at 10% ethanol in water   [g/kg]  
ethanol study
Data set, strains Finn1   inbred   22 strains     sex: both     age: 8-9wks
Procedure bottle choice test
Ontology mappings

  STRAIN COMPARISON PLOT
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Finn1 - dose of ethanol voluntarily consumed at 10% ethanol in water



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains22 strains
Mean of the strain means5.11   g/kg 3.25   g/kg
Median of the strain means3.03   g/kg 2.27   g/kg
SD of the strain means± 4.58 ± 3.27
Coefficient of variation (CV)0.896 1.01
Min–max range of strain means0.819   –   17.4   g/kg 0.390   –   14.0   g/kg
Mean sample size per strain7.5   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 322.0468 322.0468 24.5409 < 0.0001
strain 21 4427.3928 210.8282 16.0657 < 0.0001
sex:strain 21 634.1292 30.1966 2.3011 0.0012
Residuals 291 3818.7462 13.1228


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.68 2.22   8 0.785 0.83 0.98, 6.58 -0.53
129S1/SvImJ m 1.96 2.04   8 0.721 1.04 0.59, 6.5 -0.39
A/J f 1.42 0.967   8 0.342 0.679 0.33, 3.48 -0.81
A/J m 1.44 1.16   8 0.41 0.804 0.63, 4.26 -0.55
BALB/cByJ f 2.43 5.17   8 1.83 2.13 0.35, 15.2 -0.59
BALB/cByJ m 2.42 3.48   8 1.23 1.44 0.27, 10.2 -0.25
BTBR T+ Itpr3tf/J f 0.819 0.588   8 0.208 0.718 0.27, 1.87 -0.94
BTBR T+ Itpr3tf/J m 0.39 0.282   8 0.0996 0.723 -0.87
BUB/BnJ f 1.09 0.34   3 0.196 0.312 0.86, 1.48 -0.88
BUB/BnJ m 0.959 0.242   7 0.0915 0.252 0.7, 1.28 -0.7
C57BL/6J f 17.4 3.41   8 1.2 0.196 12.1, 21.3 2.68
C57BL/6J m 14.0 3.28   8 1.16 0.235 8.81, 18.6 3.29
C57BLKS/J f 7.98 5.76   8 2.04 0.722 2.13, 17.1 0.63
C57BLKS/J m 8.07 4.92   7 1.86 0.61 0.63, 15.6 1.48
C58/J f 12.4 4.07   8 1.44 0.327 7.45, 17.8 1.59
C58/J m 9.44 7.82   7 2.96 0.829 0.89, 20.1 1.89
CZECHII/EiJ f 9.26 11.8   4 5.89 1.27 0.49, 26.6 0.9
CZECHII/EiJ m 3.27 2.05   5 0.917 0.628 1.45, 6.29 0.01
DBA/2J f 0.851 0.241   8 0.0851 0.283 0.42, 1.21 -0.93
DBA/2J m 0.919 0.414   8 0.146 0.451 0.36, 1.73 -0.71
FVB/NJ f 3.27 4.67   8 1.65 1.43 0.36, 13.8 -0.4
FVB/NJ m 2.31 3.59   8 1.27 1.55 -0.29
I/LnJ f 1.99 1.07   8 0.377 0.535 0.94, 3.95 -0.68
I/LnJ m 2.23 1.7   8 0.601 0.763 0.97, 5.81 -0.31
LP/J f 1.58 0.833   8 0.294 0.526 0.71, 3.04 -0.77
LP/J m 1.97 1.69   8 0.596 0.855 0.82, 5.34 -0.39
MA/MyJ f 2.79 2.99   8 1.06 1.07 0.75, 7.97 -0.51
MA/MyJ m 2.71 2.91   8 1.03 1.07 0.57, 8.28 -0.16
NOD/ShiLtJ f 6.84 6.54   8 2.31 0.957 0.35, 21.3 0.38
NOD/ShiLtJ m 3.88 2.71   8 0.958 0.698 0.85, 8.03 0.19
NON/ShiLtJ f 3.3 3.6   8 1.27 1.09 0.61, 11.6 -0.4
NON/ShiLtJ m 0.988 0.682   8 0.241 0.691 0.24, 2.56 -0.69
NZB/BlNJ f 9.23 2.14   8 0.758 0.232 6.58, 13.0 0.9
NZB/BlNJ m 4.52 3.34   8 1.18 0.738 0.39
NZW/LacJ f 1.24 1.76   6 0.719 1.42 -0.85
NZW/LacJ m 3.27 3.07   10 0.972 0.94 0.43, 9.89 0.01
PERA/EiJ f 6.66 3.62   5 1.62 0.543 1.51, 9.93 0.34
PERA/EiJ m 1.88 1.6   9 0.532 0.848 0.7, 5.13 -0.42
RIIIS/J f 5.94 5.22   8 1.85 0.879 1.46, 16.9 0.18
RIIIS/J m 2.68 3.28   8 1.16 1.22 0.32, 8.81 -0.17
SEA/GnJ f 1.42 2.03   8 0.717 1.43 0.29, 6.21 -0.81
SEA/GnJ m 1.01 0.862   8 0.305 0.85 -0.69
SM/J f 11.9 8.92   8 3.15 0.751 1.13, 21.8 1.48
SM/J m 1.15 1.11   8 0.392 0.963 -0.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.6775 1.2808 5.1982 0.1568
129S1/SvImJ m 1.9638 1.2808 4.4845 0.0
A/J f 1.4225 1.2808 3.9432 0.0
A/J m 1.4425 1.2808 3.9632 0.0
BALB/cByJ f 2.4275 1.2808 4.9482 0.0
BALB/cByJ m 2.4163 1.2808 4.937 0.0
BTBR T+ Itpr3tf/J f 0.8188 1.2808 3.3395 0.0
BTBR T+ Itpr3tf/J m 0.39 1.2808 2.9107 0.0
BUB/BnJ f 1.09 2.0915 5.2063 0.0
BUB/BnJ m 0.9586 1.3692 3.6533 0.0
C57BL/6J f 17.35 1.2808 19.8707 14.8293
C57BL/6J m 14.0013 1.2808 16.522 11.4805
C57BLKS/J f 7.9787 1.2808 10.4995 5.458
C57BLKS/J m 8.0657 1.3692 10.7605 5.3709
C58/J f 12.45 1.2808 14.9707 9.9293
C58/J m 9.4371 1.3692 12.1319 6.7424
CZECHII/EiJ f 9.2575 1.8113 12.8224 5.6926
CZECHII/EiJ m 3.266 1.6201 6.4545 0.0775
DBA/2J f 0.8513 1.2808 3.372 0.0
DBA/2J m 0.9188 1.2808 3.4395 0.0
FVB/NJ f 3.27 1.2808 5.7907 0.7493
FVB/NJ m 2.31 1.2808 4.8307 0.0
I/LnJ f 1.9925 1.2808 4.5132 0.0
I/LnJ m 2.2275 1.2808 4.7482 0.0
LP/J f 1.5838 1.2808 4.1045 0.0
LP/J m 1.9713 1.2808 4.492 0.0
MA/MyJ f 2.7875 1.2808 5.3082 0.2668
MA/MyJ m 2.7112 1.2808 5.232 0.1905
NOD/ShiLtJ f 6.8375 1.2808 9.3582 4.3168
NOD/ShiLtJ m 3.8825 1.2808 6.4032 1.3618
NON/ShiLtJ f 3.3 1.2808 5.8207 0.7793
NON/ShiLtJ m 0.9875 1.2808 3.5082 0.0
NZB/BlNJ f 9.2262 1.2808 11.747 6.7055
NZB/BlNJ m 4.525 1.2808 7.0457 2.0043
NZW/LacJ f 1.2417 1.4789 4.1524 0.0
NZW/LacJ m 3.269 1.1455 5.5236 1.0144
PERA/EiJ f 6.664 1.6201 9.8525 3.4755
PERA/EiJ m 1.8833 1.2075 4.2599 0.0
RIIIS/J f 5.9413 1.2808 8.462 3.4205
RIIIS/J m 2.6825 1.2808 5.2032 0.1618
SEA/GnJ f 1.4175 1.2808 3.9382 0.0
SEA/GnJ m 1.0138 1.2808 3.5345 0.0
SM/J f 11.8725 1.2808 14.3932 9.3518
SM/J m 1.1513 1.2808 3.672 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.3206 0.9056 4.1031 0.5382
A/J both 1.4325 0.9056 3.2149 0.0
BALB/cByJ both 2.4219 0.9056 4.2043 0.6394
BTBR T+ Itpr3tf/J both 0.6044 0.9056 2.3868 0.0
BUB/BnJ both 1.0243 1.2499 3.4843 0.0
C57BL/6J both 15.6756 0.9056 17.4581 13.8932
C57BLKS/J both 8.0222 0.9374 9.8672 6.1772
C58/J both 10.9436 0.9374 12.7886 9.0986
CZECHII/EiJ both 6.2618 1.215 8.6531 3.8704
DBA/2J both 0.885 0.9056 2.6674 0.0
FVB/NJ both 2.79 0.9056 4.5724 1.0076
I/LnJ both 2.11 0.9056 3.8924 0.3276
LP/J both 1.7775 0.9056 3.5599 0.0
MA/MyJ both 2.7494 0.9056 4.5318 0.9669
NOD/ShiLtJ both 5.36 0.9056 7.1424 3.5776
NON/ShiLtJ both 2.1438 0.9056 3.9262 0.3613
NZB/BlNJ both 6.8756 0.9056 8.6581 5.0932
NZW/LacJ both 2.2553 0.9353 4.0962 0.4144
PERA/EiJ both 4.2737 1.0103 6.262 2.2853
RIIIS/J both 4.3119 0.9056 6.0943 2.5294
SEA/GnJ both 1.2156 0.9056 2.9981 0.0
SM/J both 6.5119 0.9056 8.2943 4.7294




  GWAS USING LINEAR MIXED MODELS