Project measure / variable:   Crabbe4   latency_screen30

ID, description, units MPD:19101   latency_screen30   latency to fall from a vertical wire mesh grid 30 min post-injection   [s]  
ethanol study
Data set, strains Crabbe4   inbred   8 strains     sex: both     age: 9-10wks
Procedure vertical wire mesh
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  STRAIN COMPARISON PLOT
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Crabbe4 - latency to fall from a vertical wire mesh grid 30 min post-injection



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means157   s 138   s
Median of the strain means140   s 144   s
SD of the strain means± 51.9 ± 64.7
Coefficient of variation (CV)0.331 0.468
Min–max range of strain means98.4   –   240   s 64.8   –   217   s
Mean sample size per strain5.1   mice 5.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3622.2561 3622.2561 0.337 0.5636
strain 7 146882.1283 20983.1612 1.952 0.0752
sex:strain 7 100411.1868 14344.4553 1.3345 0.2484
Residuals 66 709455.4167 10749.3245


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 204.0 89.0   6 36.3 0.437 22.0, 240.0 0.92
129S1/SvImJ m 217.0 55.9   6 22.8 0.258 103.0, 240.0 1.22
A/J f 199.0 92.1   5 41.2 0.463 34.0, 240.0 0.82
A/J m 164.0 103.0   6 41.9 0.626 23.0, 240.0 0.4
BALB/cByJ f 127.0 124.0   6 50.5 0.972 7.0, 240.0 -0.57
BALB/cByJ m 203.0 91.4   6 37.3 0.451 16.0, 240.0 1.0
BTBR T+ Itpr3tf/J f 104.0 125.0   5 55.7 1.2 9.0, 240.0 -1.01
BTBR T+ Itpr3tf/J m 71.2 113.0   4 56.3 1.58 7.0, 240.0 -1.04
C3H/HeJ f 240.0 0.0   5 0.0 0.0 240.0, 240.0 1.61
C3H/HeJ m 67.2 98.1   5 43.9 1.46 11.0, 240.0 -1.1
C57BL/6J f 98.4 129.0   5 57.8 1.31 2.0, 240.0 -1.12
C57BL/6J m 64.8 101.0   5 45.0 1.55 4.0, 240.0 -1.14
DBA/2J f 129.0 128.0   4 64.2 0.994 4.0, 240.0 -0.53
DBA/2J m 125.0 133.0   4 66.3 1.06 8.0, 240.0 -0.21
FVB/NJ f 151.0 121.0   5 54.3 0.802 14.0, 240.0 -0.11
FVB/NJ m 194.0 103.0   5 46.0 0.53 10.0, 240.0 0.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 203.6667 42.3268 288.1748 119.1586
129S1/SvImJ m 217.1667 42.3268 301.6748 132.6586
A/J f 198.8 46.3666 291.374 106.226
A/J m 163.8333 42.3268 248.3414 79.3252
BALB/cByJ f 127.1667 42.3268 211.6748 42.6586
BALB/cByJ m 202.6667 42.3268 287.1748 118.1586
BTBR T+ Itpr3tf/J f 103.6 46.3666 196.174 11.026
BTBR T+ Itpr3tf/J m 71.25 51.8395 174.7509 0.0
C3H/HeJ f 240.0 46.3666 332.574 147.426
C3H/HeJ m 67.2 46.3666 159.774 0.0
C57BL/6J f 98.4 46.3666 190.974 5.826
C57BL/6J m 64.8 46.3666 157.374 0.0
DBA/2J f 129.25 51.8395 232.7509 25.7491
DBA/2J m 125.25 51.8395 228.7509 21.7491
FVB/NJ f 151.4 46.3666 243.974 58.826
FVB/NJ m 194.0 46.3666 286.574 101.426


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 210.4167 29.9295 270.1729 150.6604
A/J both 181.3167 31.3904 243.9895 118.6438
BALB/cByJ both 164.9167 29.9295 224.6729 105.1604
BTBR T+ Itpr3tf/J both 87.425 34.775 156.8555 17.9945
C3H/HeJ both 153.6 32.7862 219.0597 88.1403
C57BL/6J both 81.6 32.7862 147.0597 16.1403
DBA/2J both 127.25 36.656 200.4362 54.0638
FVB/NJ both 172.7 32.7862 238.1597 107.2403




  GWAS USING LINEAR MIXED MODELS