Phenotype measure:   Finn1   6pct_EtOH

ID, description, units MPD:25602   6pct_EtOH   dose of ethanol voluntarily consumed at 6% ethanol in water   [g/kg]
ethanol study
Data set, strains Finn1   inbred   22 strains     sex: both     age: 8-9wks
Procedure bottle choice test
Ontology mappings

  STRAIN COMPARISON PLOT
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Finn1 - dose of ethanol voluntarily consumed at 6% ethanol in water



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains22 strains
Mean of the strain means4.85   g/kg 2.66   g/kg
Median of the strain means1.93   g/kg 1.39   g/kg
SD of the strain means± 4.71 ± 2.67
Coefficient of variation (CV)0.970 1.00
Min–max range of strain means0.409   –   13.6   g/kg 0.167   –   8.82   g/kg
Mean sample size per strain7.5   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 373.3096 373.3096 63.8968 < 0.0001
strain 21 3818.9905 181.8567 31.1272 < 0.0001
sex:strain 21 547.2913 26.0615 4.4608 < 0.0001
Residuals 291 1700.1328 5.8424


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.74 1.75   8 0.618 1.0 0.21, 5.24 -0.66
129S1/SvImJ m 1.64 1.36   8 0.479 0.824 0.35, 3.57 -0.38
A/J f 0.502 0.393   8 0.139 0.782 -0.92
A/J m 0.596 0.939   8 0.332 1.57 -0.77
BALB/cByJ f 0.546 0.27   8 0.0955 0.495 0.2, 1.1 -0.91
BALB/cByJ m 0.735 0.714   8 0.252 0.972 0.33, 2.48 -0.72
BTBR T+ Itpr3tf/J f 0.515 0.334   8 0.118 0.649 -0.92
BTBR T+ Itpr3tf/J m 0.289 0.141   8 0.0498 0.488 0.14, 0.46 -0.89
BUB/BnJ f 1.25 1.38   3 0.794 1.1 0.35, 2.83 -0.77
BUB/BnJ m 0.167 0.193   7 0.0728 1.15 -0.93
C57BL/6J f 13.6 1.48   7 0.559 0.109 11.2, 15.6 1.86
C57BL/6J m 8.82 3.04   8 1.07 0.344 3.48, 12.2 2.31
C57BLKS/J f 8.5 2.19   8 0.775 0.258 6.23, 12.2 0.78
C57BLKS/J m 7.72 3.68   7 1.39 0.477 0.37, 10.5 1.9
C58/J f 10.5 3.03   8 1.07 0.289 6.38, 15.9 1.2
C58/J m 7.24 5.42   7 2.05 0.748 0.78, 15.4 1.72
CZECHII/EiJ f 13.0 2.45   4 1.22 0.188 11.0, 16.3 1.73
CZECHII/EiJ m 4.24 2.32   6 0.947 0.547 0.86, 7.01 0.59
DBA/2J f 0.989 0.288   8 0.102 0.291 0.5, 1.46 -0.82
DBA/2J m 0.774 0.231   8 0.0816 0.298 0.42, 1.07 -0.71
FVB/NJ f 2.12 2.42   8 0.856 1.14 0.41, 7.15 -0.58
FVB/NJ m 0.78 0.73   8 0.258 0.936 0.2, 2.3 -0.7
I/LnJ f 0.72 0.394   8 0.139 0.547 -0.88
I/LnJ m 0.506 0.681   8 0.241 1.34 -0.81
LP/J f 0.981 1.03   8 0.365 1.05 -0.82
LP/J m 1.14 1.97   8 0.697 1.73 0.15, 6.0 -0.57
MA/MyJ f 5.47 3.89   8 1.38 0.711 0.65, 12.9 0.13
MA/MyJ m 1.98 3.05   8 1.08 1.54 -0.25
NOD/ShiLtJ f 11.4 5.29   8 1.87 0.464 1.07, 17.3 1.39
NOD/ShiLtJ m 5.42 3.58   8 1.27 0.661 0.72, 10.3 1.04
NON/ShiLtJ f 1.48 1.51   8 0.532 1.02 0.66, 5.07 -0.72
NON/ShiLtJ m 0.77 0.102   8 0.0359 0.132 0.59, 0.9 -0.71
NZB/BlNJ f 7.89 2.28   8 0.806 0.289 4.89, 11.1 0.65
NZB/BlNJ m 5.64 2.12   8 0.748 0.375 1.6, 8.82 1.12
NZW/LacJ f 0.548 0.213   6 0.0868 0.388 0.16, 0.75 -0.91
NZW/LacJ m 0.729 0.488   10 0.154 0.669 0.14, 1.73 -0.72
PERA/EiJ f 8.95 4.31   5 1.93 0.482 1.95, 12.3 0.87
PERA/EiJ m 2.24 1.51   9 0.503 0.674 1.11, 5.35 -0.16
RIIIS/J f 5.93 2.73   8 0.966 0.46 1.74, 9.29 0.23
RIIIS/J m 3.0 1.95   8 0.691 0.652 0.85, 5.99 0.13
SEA/GnJ f 0.409 0.368   8 0.13 0.901 -0.94
SEA/GnJ m 0.979 2.05   8 0.724 2.09 -0.63
SM/J f 9.69 5.37   8 1.9 0.554 1.43, 15.9 1.03
SM/J m 3.01 4.48   8 1.58 1.49 0.22, 10.8 0.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.7388 0.8546 3.4207 0.0568
129S1/SvImJ m 1.645 0.8546 3.3269 0.0
A/J f 0.5025 0.8546 2.1844 0.0
A/J m 0.5962 0.8546 2.2782 0.0
BALB/cByJ f 0.5463 0.8546 2.2282 0.0
BALB/cByJ m 0.735 0.8546 2.4169 0.0
BTBR T+ Itpr3tf/J f 0.515 0.8546 2.1969 0.0
BTBR T+ Itpr3tf/J m 0.2887 0.8546 1.9707 0.0
BUB/BnJ f 1.2467 1.3955 3.9932 0.0
BUB/BnJ m 0.1671 0.9136 1.9652 0.0
C57BL/6J f 13.6143 0.9136 15.4123 11.8162
C57BL/6J m 8.8188 0.8546 10.5007 7.1368
C57BLKS/J f 8.505 0.8546 10.1869 6.8231
C57BLKS/J m 7.7214 0.9136 9.5195 5.9234
C58/J f 10.49 0.8546 12.1719 8.8081
C58/J m 7.2443 0.9136 9.0423 5.4462
CZECHII/EiJ f 13.0 1.2086 15.3786 10.6214
CZECHII/EiJ m 4.2433 0.9868 6.1855 2.3012
DBA/2J f 0.9887 0.8546 2.6707 0.0
DBA/2J m 0.7737 0.8546 2.4557 0.0
FVB/NJ f 2.1187 0.8546 3.8007 0.4368
FVB/NJ m 0.78 0.8546 2.4619 0.0
I/LnJ f 0.72 0.8546 2.4019 0.0
I/LnJ m 0.5063 0.8546 2.1882 0.0
LP/J f 0.9813 0.8546 2.6632 0.0
LP/J m 1.1375 0.8546 2.8194 0.0
MA/MyJ f 5.4725 0.8546 7.1544 3.7906
MA/MyJ m 1.9837 0.8546 3.6657 0.3018
NOD/ShiLtJ f 11.3987 0.8546 13.0807 9.7168
NOD/ShiLtJ m 5.4162 0.8546 7.0982 3.7343
NON/ShiLtJ f 1.4825 0.8546 3.1644 0.0
NON/ShiLtJ m 0.77 0.8546 2.4519 0.0
NZB/BlNJ f 7.895 0.8546 9.5769 6.2131
NZB/BlNJ m 5.6437 0.8546 7.3257 3.9618
NZW/LacJ f 0.5483 0.9868 2.4905 0.0
NZW/LacJ m 0.729 0.7644 2.2334 0.0
PERA/EiJ f 8.948 1.081 11.0755 6.8205
PERA/EiJ m 2.2367 0.8057 3.8224 0.6509
RIIIS/J f 5.935 0.8546 7.6169 4.2531
RIIIS/J m 2.9975 0.8546 4.6794 1.3156
SEA/GnJ f 0.4088 0.8546 2.0907 0.0
SEA/GnJ m 0.9788 0.8546 2.6607 0.0
SM/J f 9.69 0.8546 11.3719 8.0081
SM/J m 3.0075 0.8546 4.6894 1.3256


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.6919 0.6043 2.8812 0.5026
A/J both 0.5494 0.6043 1.7387 0.0
BALB/cByJ both 0.6406 0.6043 1.8299 0.0
BTBR T+ Itpr3tf/J both 0.4019 0.6043 1.5912 0.0
BUB/BnJ both 0.7069 0.834 2.3483 0.0
C57BL/6J both 11.2165 0.6255 12.4476 9.9855
C57BLKS/J both 8.1132 0.6255 9.3443 6.8822
C58/J both 8.8671 0.6255 10.0982 7.6361
CZECHII/EiJ both 8.6217 0.7801 10.1571 7.0863
DBA/2J both 0.8812 0.6043 2.0706 0.0
FVB/NJ both 1.4494 0.6043 2.6387 0.2601
I/LnJ both 0.6131 0.6043 1.8024 0.0
LP/J both 1.0594 0.6043 2.2487 0.0
MA/MyJ both 3.7281 0.6043 4.9174 2.5388
NOD/ShiLtJ both 8.4075 0.6043 9.5968 7.2182
NON/ShiLtJ both 1.1262 0.6043 2.3156 0.0
NZB/BlNJ both 6.7694 0.6043 7.9587 5.5801
NZW/LacJ both 0.6387 0.6241 1.867 0.0
PERA/EiJ both 5.5923 0.6741 6.9191 4.2656
RIIIS/J both 4.4663 0.6043 5.6556 3.2769
SEA/GnJ both 0.6938 0.6043 1.8831 0.0
SM/J both 6.3488 0.6043 7.5381 5.1594




  GWAS USING LINEAR MIXED MODELS