Intervention:   cocaine          

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg) Year
    Dickson2 54831 operant conditioning chamber cocaine intravenous self-administration, mean number of infusions (fixed ratio 1 (FR1) schedule), over ten 120 min sessions   [n]  FR1_infusions_mean DO population both 12-16wks N=35 2015
    Dickson2 54832 operant conditioning chamber cocaine intravenous self-administration, mean number of responses on the active lever (fixed ratio 1 (FR1) schedule), over ten 120 min sessions   [n]  FR1_active_mean DO population both 12-16wks N=35 2015
    Dickson2 54833 operant conditioning chamber cocaine intravenous self-administration, mean number of responses on the inactive lever (fixed ratio 1 (FR1) schedule), over ten 120 min sessions   [n]  FR1_inactive_mean DO population both 12-16wks N=35 2015
    Dickson2 54841 operant conditioning chamber cocaine intravenous self-administration, breakpoint for infusions (progressive ratio (PR) schedule), one 6h test   [n]  PR_infusions_breakpoint DO population both 12-16wks N=31 2015
    Dickson2 54842 operant conditioning chamber cocaine intravenous self-administration, number of presses on the active lever (progressive ratio (PR) schedule), one 6h test   [n]  PR_active DO population both 12-16wks N=31 2015
    Dickson2 54843 operant conditioning chamber cocaine intravenous self-administration, number of presses on the inactive lever (progressive ratio (PR) schedule), one 6h test   [n]  PR_inactive DO population both 12-16wks N=31 2015
    Jentsch2 49701 operant conditioning chamber cocaine number of sessions (days) required to reach criteria for self-administration (FR1 reinforcement schedule)   [d]  acquisition_FR1 BXD 4 both 8-17wks N=8 2013
    Jentsch2 49702 operant conditioning chamber cocaine Fixed ratio 1 - self administration   [n]     day 1    day 3    day 5    last day BXD 4 both 8-17wks N=8 2013
    Jentsch2 49706 operant conditioning chamber cocaine Fixed ratio 1 - discrimination index   [%]     day 1    day 3    day 5    last day BXD 4 both 8-17wks N=7 2013
    Jentsch2 49710 operant conditioning chamber cocaine Fixed ratio 1 - time-out response   [n]     day 1    day 3    day 5    last day BXD 4 both 8-17wks N=7 2013
    Jentsch2 49714 operant conditioning chamber cocaine Fixed ratio 2 - self administration   [n]     day 1    day 2    day 4 BXD 4 both 8-17wks N=6 2013
    Jentsch2 49717 operant conditioning chamber cocaine Fixed ratio 2 - discrimination index   [%]     day 1    day 2    day 4 BXD 4 both 8-17wks N=6 2013
    Jentsch2 49720 operant conditioning chamber cocaine Fixed ratio 2 - time-out response   [n]     day 1    day 2    day 4 BXD 4 both 8-17wks N=6 2013
    Jentsch2 49723 operant conditioning chamber cocaine Fixed ratio 5 - self administration   [n]     day 1    day 3    day 5 BXD 4 both 8-17wks N=6 2013
    Jentsch2 49726 operant conditioning chamber cocaine Fixed ratio 5 - discrimination index   [%]     day 1    day 3    day 5 BXD 4 both 8-17wks N=6 2013
    Jentsch2 49729 operant conditioning chamber cocaine Fixed ratio 5 - time-out response   [n]     day 1    day 3    day 5 BXD 4 both 8-17wks N=6 2013
    Jentsch2 49732 operant conditioning chamber cocaine horizontal beam breaks   [n]     baseline    5 mg/kg    10 mg/kg    20 mg/kg BXD 4 f 8-17wks N=13 2013
Kumar1 29001 circadian wheel running cocaine cocaine response over 30 minutes; data are averaged in 5 minute bins and then summed over 30 minutes   [cm x 100]  1sum_5min_avg QTL population both 10-14wks N=122 2014
Kumar1 29002 circadian wheel running cocaine cocaine response over 60 minutes; data are averaged in 5 minute bins and then summed over 60 minutes   [cm x 100]  1sum_60min QTL population both 10-14wks N=122 2014
Kumar1 29004 circadian wheel running cocaine average speed over 30 minutes after cocaine response   [cm x 100 / min]  130avg QTL population both 10-14wks N=122 2014
Kumar1 29005 circadian wheel running cocaine net response–baselineavg subtracted from 30avg   [cm x 100 / min]  1resp-baseline QTL population both 10-14wks N=122 2014
    Tarantino1 45911 open field test cocaine distance traveled, 30 min test   [cm]     baseline    treated    difference inbred 45 m 8-11wks N=18 2015
    Tarantino1 45916 open field test cocaine ambulatory episodes, 30 min test   [n]     baseline    treated    difference inbred 45 m 8-11wks N=18 2015
    Tarantino1 45921 open field test cocaine rearing episodes, 30 min test   [n]     baseline    treated    difference inbred 45 m 8-11wks N=18 2015
    Tarantino1 45926 open field test cocaine average velocity, 30 min test   [cm/s]     baseline    treated    difference inbred 45 m 8-11wks N=18 2015
    Tarantino1 45931 open field test cocaine resting, 30 min test   [%]     baseline    treated    difference inbred 45 m 8-11wks N=18 2015
    Thomsen1 40701 open field test cocaine total activity, test 1   [n]     baseline    dose mg/kg i.p.:    3    10    18    32    56 inbred 15 both 8-10wks N=8 2011
    Thomsen1 40707 open field test cocaine total activity, test 2   [n]     baseline    dose mg/kg i.p.:    3    10    32 inbred 15 both 8-10wks N=8 2011
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