Project measure / variable:   CSNA03   acquisition_cc

ID, description, units MPD:110390   acquisition_cc   number of sessions to acquisition (1.0 mg/kg) (intravenous self administration), CC   [n]  
cocaine study
Data set, strains CSNA03   CC w/par   53 strains     sex: both     age: 4-25wks
Procedure operant conditioning chamber
Ontology mappings

  STRAIN COMPARISON PLOT
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CSNA03 - number of sessions to acquisition (1.0 mg/kg) (intravenous self administration), CC



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested49 strains48 strains
Mean of the strain means8.7578   n 8.8792   n
Median of the strain means7.8333   n 7.9444   n
SD of the strain means± 3.9695 ± 3.1486
Coefficient of variation (CV)0.4532 0.3546
Min–max range of strain means5.0   –   29.0   n 5.0   –   21.0   n
Mean sample size per strain3.7   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.2773 1.2773 0.0671 0.7958
strain 34 1675.3997 49.2765 2.5884 < 0.0001
sex:strain 34 330.1018 9.7089 0.51 0.9899
Residuals 261 4968.7016 19.0372


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 12.667 7.2405   12 2.0901 0.5716 5.0, 28.0 0.98
A/J m 12.333 6.6895   9 2.2298 0.5424 5.0, 24.0 1.1
C57BL/6J f 12.077 7.6427   13 2.1197 0.6328 5.0, 27.0 0.84
C57BL/6J m 9.6154 4.9756   13 1.38 0.5175 5.0, 24.0 0.23
CAST/EiJ f 9.125 4.8237   8 1.7054 0.5286 5.0, 20.0 0.09
CAST/EiJ m 7.5 1.0   4 0.5 0.1333 6.0, 8.0 -0.44
CC001/UncJ f 11.25 4.717   4 2.3585 0.4193 7.0, 18.0 0.63
CC001/UncJ m 6.75 0.95743   4 0.47871 0.1418 6.0, 8.0 -0.68
CC002/UncJ f 7.0 3.4641   3 2.0 0.4949 5.0, 11.0 -0.44
CC002/UncJ m 6.0 1.4142   2   1.0 0.2357 5.0, 7.0 -0.91
CC003/UncJ f 10.0 0.0   1   0.0 0.0 10.0, 10.0 0.31
CC003/UncJ m 8.3333 1.5275   3 0.88192 0.1833 7.0, 10.0 -0.17
CC004/TauUncJ f 7.8333 3.2146   12 0.92796 0.4104 5.0, 17.0 -0.23
CC004/TauUncJ m 7.1429 2.2646   21 0.49418 0.317 5.0, 12.0 -0.55
CC005/TauUncJ f 7.25 1.893   4 0.94648 0.2611 6.0, 10.0 -0.38
CC005/TauUncJ m 9.3333 4.9329   3 2.848 0.5285 6.0, 15.0 0.14
CC006/TauUncJ f 7.5 3.5355   2   2.5 0.4714 5.0, 10.0 -0.32
CC006/TauUncJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.91
CC007/UncJ f 5.5 0.70711   2   0.5 0.1286 5.0, 6.0 -0.82
CC007/UncJ m 5.5 0.70711   2   0.5 0.1286 5.0, 6.0 -1.07
CC008/GeniUncJ f 10.0 0.0   1   0.0 0.0 10.0, 10.0 0.31
CC008/GeniUncJ m 12.0 1.4142   2   1.0 0.1179 11.0, 13.0 0.99
CC009/UncJ f 5.5 0.70711   2   0.5 0.1286 5.0, 6.0 -0.82
CC009/UncJ m 11.5 4.9497   2   3.5 0.4304 8.0, 15.0 0.83
CC011/UncJ f 9.75 5.7373   4 2.8687 0.5884 5.0, 18.0 0.25
CC011/UncJ m 7.4 2.3022   5 1.0296 0.3111 5.0, 10.0 -0.47
CC012/GeniUncJ f 9.5 2.1213   2   1.5 0.2233 8.0, 11.0 0.19
CC012/GeniUncJ m 14.0 0.0   1   0.0 0.0 14.0, 14.0 1.63
CC013/GeniUncJ f 6.0 0.0   3 0.0 0.0 6.0, 6.0 -0.69
CC013/GeniUncJ m 8.6667 3.7859   3 2.1858 0.4368 6.0, 13.0 -0.07
CC015/UncJ f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.69
CC015/UncJ m 9.0 0.0   1   0.0 0.0 9.0, 9.0 0.04
CC016/GeniUncJ f 9.0 4.2426   2   3.0 0.4714 6.0, 12.0 0.06
CC016/GeniUncJ m 10.5 3.5355   2   2.5 0.3367 8.0, 13.0 0.51
CC017/UncJ f 9.3333 4.9329   3 2.848 0.5285 6.0, 15.0 0.14
CC017/UncJ m 9.5 6.364   2   4.5 0.6699 5.0, 14.0 0.2
CC018/UncJ f 5.0 0.0   2   0.0 0.0 5.0, 5.0 -0.95
CC018/UncJ m 6.4 0.89443   5 0.4 0.1398 5.0, 7.0 -0.79
CC019/TauUncJ f 6.2 1.3038   5 0.5831 0.2103 5.0, 8.0 -0.64
CC019/TauUncJ m 7.3333 2.5166   3 1.453 0.3432 5.0, 10.0 -0.49
CC020/GeniUncJ f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.95
CC023/GeniUncJ f 10.5 0.70711   2   0.5 0.0673 10.0, 11.0 0.44
CC023/GeniUncJ m 10.333 6.1101   3 3.5277 0.5913 5.0, 17.0 0.46
CC024/GeniUncJ f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.19
CC024/GeniUncJ m 13.0 0.0   1   0.0 0.0 13.0, 13.0 1.31
CC025/GeniUncJ f 10.0 7.0711   2   5.0 0.7071 5.0, 15.0 0.31
CC025/GeniUncJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.91
CC026/GeniUncJ f 14.8 5.9749   5 2.6721 0.4037 10.0, 25.0 1.52
CC026/GeniUncJ m 13.333 3.2146   3 1.8559 0.2411 11.0, 17.0 1.41
CC027/GeniUncJ f 5.0 0.0   3 0.0 0.0 5.0, 5.0 -0.95
CC027/GeniUncJ m 9.0 4.1833   5 1.8708 0.4648 5.0, 16.0 0.04
CC028/GeniUncJ f 6.6 0.89443   5 0.4 0.1355 6.0, 8.0 -0.54
CC028/GeniUncJ m 8.5 3.4496   6 1.4083 0.4058 5.0, 15.0 -0.12
CC029/UncJ m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -1.23
CC030/GeniUncJ f 6.0 1.4142   2   1.0 0.2357 5.0, 7.0 -0.69
CC030/GeniUncJ m 7.0 2.8284   2   2.0 0.4041 5.0, 9.0 -0.6
CC032/GeniUncJ f 5.3333 0.57735   3 0.33333 0.1083 5.0, 6.0 -0.86
CC032/GeniUncJ m 7.0 3.3665   4 1.6833 0.4809 5.0, 12.0 -0.6
CC033/GeniUncJ f 9.0 0.0   1   0.0 0.0 9.0, 9.0 0.06
CC033/GeniUncJ m 11.5 4.9497   2   3.5 0.4304 8.0, 15.0 0.83
CC035/UncJ f 6.6667 2.8868   3 1.6667 0.433 5.0, 10.0 -0.53
CC035/UncJ m 5.5 0.70711   2   0.5 0.1286 5.0, 6.0 -1.07
CC036/UncJ f 7.0 2.6458   3 1.5275 0.378 5.0, 10.0 -0.44
CC036/UncJ m 13.0 0.0   2   0.0 0.0 13.0, 13.0 1.31
CC040/TauUncJ f 9.5 3.5355   2   2.5 0.3722 7.0, 12.0 0.19
CC040/TauUncJ m 5.0 0.0   2   0.0 0.0 5.0, 5.0 -1.23
CC041/TauUncJ f 29.0 0.0   1   0.0 0.0 29.0, 29.0 5.1
CC041/TauUncJ m 21.0 0.0   1   0.0 0.0 21.0, 21.0 3.85
CC043/GeniUncJ m 9.5 3.5355   2   2.5 0.3722 7.0, 12.0 0.2
CC045/GeniUncJ f 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.44
CC051/TauUncJ f 5.0 0.0   2   0.0 0.0 5.0, 5.0 -0.95
CC051/TauUncJ m 5.0 0.0   3 0.0 0.0 5.0, 5.0 -1.23
CC057/UncJ f 7.0 2.8284   2   2.0 0.4041 5.0, 9.0 -0.44
CC057/UncJ m 9.5 4.9497   2   3.5 0.521 6.0, 13.0 0.2
CC059/TauUncJ f 6.25 1.5   4 0.75 0.24 5.0, 8.0 -0.63
CC059/TauUncJ m 7.5 3.0   4 1.5 0.4 5.0, 11.0 -0.44
CC060/UncJ m 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.6
CC061/GeniUncJ f 8.0 0.0   2   0.0 0.0 8.0, 8.0 -0.19
CC061/GeniUncJ m 10.0 7.0711   2   5.0 0.7071 5.0, 15.0 0.36
CC068/TauUncJ f 15.0 0.0   1   0.0 0.0 15.0, 15.0 1.57
CC074/UncJ m 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.6
CC075/UncJ f 14.0 0.0   1   0.0 0.0 14.0, 14.0 1.32
CC078/TauUncJ f 5.0 0.0   2   0.0 0.0 5.0, 5.0 -0.95
CC078/TauUncJ m 5.0 0.0   2   0.0 0.0 5.0, 5.0 -1.23
CC079/TauUncJ f 8.5 4.9497   2   3.5 0.5823 5.0, 12.0 -0.06
CC079/TauUncJ m 12.5 3.5355   2   2.5 0.2828 10.0, 15.0 1.15
CC080/TauUncJ f 11.0 1.4142   2   1.0 0.1286 10.0, 12.0 0.56
CC084/TauJ f 7.5 3.5355   2   2.5 0.4714 5.0, 10.0 -0.32
CC084/TauJ m 7.0 0.0   3 0.0 0.0 7.0, 7.0 -0.6
NOD/ShiLtJ f 9.1538 5.942   13 1.648 0.6491 5.0, 21.0 0.1
NOD/ShiLtJ m 7.5556 2.0683   9 0.68943 0.2737 5.0, 11.0 -0.42
NZO/HlLtJ f 6.4615 2.367   13 0.65648 0.3663 5.0, 13.0 -0.58
NZO/HlLtJ m 7.1818 1.7215   11 0.51906 0.2397 5.0, 10.0 -0.54
PWK/PhJ f 7.1818 2.7502   11 0.82922 0.3829 5.0, 14.0 -0.4
PWK/PhJ m 7.3636 3.1709   11 0.95606 0.4306 5.0, 14.0 -0.48
WSB/EiJ f 13.2 9.0664   5 4.0546 0.6869 5.0, 27.0 1.12
WSB/EiJ m 14.125 8.4251   8 2.9787 0.5965 5.0, 27.0 1.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 12.6666666667 1.2595359857 15.1468123308 10.1865210026
A/J m 12.3333333333 1.4543868807 15.1971588669 9.4695077997
C57BL/6J f 12.0769230769 1.2101230322 14.4597699551 9.6940761988
C57BL/6J m 9.6153846154 1.2101230322 11.9982314935 7.2325377372
CAST/EiJ f 9.125 1.5426102388 12.1625456824 6.0874543176
CAST/EiJ m 7.5 2.1815803211 11.7957383004 3.2042616996
CC001/UncJ f 11.25 2.1815803211 15.5457383004 6.9542616996
CC001/UncJ m 6.75 2.1815803211 11.0457383004 2.4542616996
CC002/UncJ f 7.0 2.5190719713 11.9602913282 2.0397086718
CC002/UncJ m 6.0 3.0852204775 12.0750913648 -0.0750913648
CC004/TauUncJ f 7.8333333333 1.2595359857 10.3134789974 5.3531876692
CC004/TauUncJ m 7.1428571429 0.9521197101 9.0176710407 5.268043245
CC005/TauUncJ f 7.25 2.1815803211 11.5457383004 2.9542616996
CC005/TauUncJ m 9.3333333333 2.5190719713 14.2936246615 4.3730420051
CC007/UncJ f 5.5 3.0852204775 11.5750913648 -0.5750913648
CC007/UncJ m 5.5 3.0852204775 11.5750913648 -0.5750913648
CC009/UncJ f 5.5 3.0852204775 11.5750913648 -0.5750913648
CC009/UncJ m 11.5 3.0852204775 17.5750913648 5.4249086352
CC011/UncJ f 9.75 2.1815803211 14.0457383004 5.4542616996
CC011/UncJ m 7.4 1.9512647586 11.2422251413 3.5577748587
CC013/GeniUncJ f 6.0 2.5190719713 10.9602913282 1.0397086718
CC013/GeniUncJ m 8.6666666667 2.5190719713 13.6269579949 3.7063753385
CC016/GeniUncJ f 9.0 3.0852204775 15.0750913648 2.9249086352
CC016/GeniUncJ m 10.5 3.0852204775 16.5750913648 4.4249086352
CC017/UncJ f 9.3333333333 2.5190719713 14.2936246615 4.3730420051
CC017/UncJ m 9.5 3.0852204775 15.5750913648 3.4249086352
CC018/UncJ f 5.0 3.0852204775 11.0750913648 -1.0750913648
CC018/UncJ m 6.4 1.9512647586 10.2422251413 2.5577748587
CC019/TauUncJ f 6.2 1.9512647586 10.0422251413 2.3577748587
CC019/TauUncJ m 7.3333333333 2.5190719713 12.2936246615 2.3730420051
CC023/GeniUncJ f 10.5 3.0852204775 16.5750913648 4.4249086352
CC023/GeniUncJ m 10.3333333333 2.5190719713 15.2936246615 5.3730420051
CC026/GeniUncJ f 14.8 1.9512647586 18.6422251413 10.9577748587
CC026/GeniUncJ m 13.3333333333 2.5190719713 18.2936246615 8.3730420051
CC027/GeniUncJ f 5.0 2.5190719713 9.9602913282 0.0397086718
CC027/GeniUncJ m 9.0 1.9512647586 12.8422251413 5.1577748587
CC028/GeniUncJ f 6.6 1.9512647586 10.4422251413 2.7577748587
CC028/GeniUncJ m 8.5 1.7812528732 12.0074556348 4.9925443652
CC030/GeniUncJ f 6.0 3.0852204775 12.0750913648 -0.0750913648
CC030/GeniUncJ m 7.0 3.0852204775 13.0750913648 0.9249086352
CC032/GeniUncJ f 5.3333333333 2.5190719713 10.2936246615 0.3730420051
CC032/GeniUncJ m 7.0 2.1815803211 11.2957383004 2.7042616996
CC035/UncJ f 6.6666666667 2.5190719713 11.6269579949 1.7063753385
CC035/UncJ m 5.5 3.0852204775 11.5750913648 -0.5750913648
CC036/UncJ f 7.0 2.5190719713 11.9602913282 2.0397086718
CC036/UncJ m 13.0 3.0852204775 19.0750913648 6.9249086352
CC040/TauUncJ f 9.5 3.0852204775 15.5750913648 3.4249086352
CC040/TauUncJ m 5.0 3.0852204775 11.0750913648 -1.0750913648
CC051/TauUncJ f 5.0 3.0852204775 11.0750913648 -1.0750913648
CC051/TauUncJ m 5.0 2.5190719713 9.9602913282 0.0397086718
CC057/UncJ f 7.0 3.0852204775 13.0750913648 0.9249086352
CC057/UncJ m 9.5 3.0852204775 15.5750913648 3.4249086352
CC059/TauUncJ f 6.25 2.1815803211 10.5457383004 1.9542616996
CC059/TauUncJ m 7.5 2.1815803211 11.7957383004 3.2042616996
CC061/GeniUncJ f 8.0 3.0852204775 14.0750913648 1.9249086352
CC061/GeniUncJ m 10.0 3.0852204775 16.0750913648 3.9249086352
CC078/TauUncJ f 5.0 3.0852204775 11.0750913648 -1.0750913648
CC078/TauUncJ m 5.0 3.0852204775 11.0750913648 -1.0750913648
CC079/TauUncJ f 8.5 3.0852204775 14.5750913648 2.4249086352
CC079/TauUncJ m 12.5 3.0852204775 18.5750913648 6.4249086352
CC084/TauJ f 7.5 3.0852204775 13.5750913648 1.4249086352
CC084/TauJ m 7.0 2.5190719713 11.9602913282 2.0397086718
NOD/ShiLtJ f 9.1538461538 1.2101230322 11.536693032 6.7709992757
NOD/ShiLtJ m 7.5555555556 1.4543868807 10.4193810892 4.691730022
NZO/HlLtJ f 6.4615384615 1.2101230322 8.8443853397 4.0786915834
NZO/HlLtJ m 7.1818181818 1.3155424319 9.7722458436 4.59139052
PWK/PhJ f 7.1818181818 1.3155424319 9.7722458436 4.59139052
PWK/PhJ m 7.3636363636 1.3155424319 9.9540640255 4.7732087018
WSB/EiJ f 13.2 1.9512647586 17.0422251413 9.3577748587
WSB/EiJ m 14.125 1.5426102388 17.1625456824 11.0874543176


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 12.5 0.9619864991 14.39424254 10.60575746
C57BL/6J both 10.8461538462 0.8556862021 12.5310810322 9.1612266601
CAST/EiJ both 8.3125 1.3359396549 10.9430917261 5.6819082739
CC001/UncJ both 9.0 1.5426102388 12.0375456824 5.9624543176
CC002/UncJ both 6.5 1.9915012548 10.4214546138 2.5785453862
CC004/TauUncJ both 7.4880952381 0.7894559585 9.0426088008 5.9335816754
CC005/TauUncJ both 8.2916666667 1.6662094927 11.5725909879 5.0107423455
CC007/UncJ both 5.5 2.1815803211 9.7957383004 1.2042616996
CC009/UncJ both 8.5 2.1815803211 12.7957383004 4.2042616996
CC011/UncJ both 8.575 1.4634485689 11.456668856 5.693331144
CC013/GeniUncJ both 7.3333333333 1.7812528732 10.8407889682 3.8258776985
CC016/GeniUncJ both 9.75 2.1815803211 14.0457383004 5.4542616996
CC017/UncJ both 9.4166666667 1.9915012548 13.3381212804 5.4952120529
CC018/UncJ both 5.7 1.8252410494 9.2940725204 2.1059274796
CC019/TauUncJ both 6.7666666667 1.5932010039 9.9038303577 3.6295029756
CC023/GeniUncJ both 10.4166666667 1.9915012548 14.3381212804 6.4952120529
CC026/GeniUncJ both 14.0666666667 1.5932010039 17.2038303577 10.9295029756
CC027/GeniUncJ both 7.0 1.5932010039 10.137163691 3.862836309
CC028/GeniUncJ both 7.55 1.3210124863 10.1511987173 4.9488012827
CC030/GeniUncJ both 6.5 2.1815803211 10.7957383004 2.2042616996
CC032/GeniUncJ both 6.1666666667 1.6662094927 9.4475909879 2.8857423455
CC035/UncJ both 6.0833333333 1.9915012548 10.0047879471 2.1618787196
CC036/UncJ both 10.0 1.9915012548 13.9214546138 6.0785453862
CC040/TauUncJ both 7.25 2.1815803211 11.5457383004 2.9542616996
CC051/TauUncJ both 5.0 1.9915012548 8.9214546138 1.0785453862
CC057/UncJ both 8.25 2.1815803211 12.5457383004 3.9542616996
CC059/TauUncJ both 6.875 1.5426102388 9.9125456824 3.8374543176
CC061/GeniUncJ both 9.0 2.1815803211 13.2957383004 4.7042616996
CC078/TauUncJ both 5.0 2.1815803211 9.2957383004 0.7042616996
CC079/TauUncJ both 10.5 2.1815803211 14.7957383004 6.2042616996
CC084/TauJ both 7.25 1.9915012548 11.1714546138 3.3285453862
NOD/ShiLtJ both 8.3547008547 0.9459966903 10.2174579465 6.4919437629
NZO/HlLtJ both 6.8216783217 0.8937350898 8.5815273717 5.0618292716
PWK/PhJ both 7.2727272727 0.9302289745 9.1044362386 5.4410183069
WSB/EiJ both 13.6625 1.243692135 16.1114476214 11.2135523786




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA