Tarantino1: Drug study: Initial locomotor sensitivity to cocaine in males of 45 inbred strains of mice (2015)

Wiltshire T, Ervin RB, Duan H, Bogue MA, Zamboni WC, Cook S, Chung W, Zou F, Tarantino LM. Initial locomotor sensitivity to cocaine varies widely among inbred mouse strains. Genes Brain Behav. 2015 Mar;14(3):271-80. doi: 10.1111/gbb.12209.   PubMed 25727211     FullText


         
Procedures conducted:
• body weight 
• open field test  Locomotor activity. Baseline (saline) vs. cocaine 20 mg/kg i.p. 30 min test.

Tarantino1 downloads
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• Download Tarantino1 strain means, SD, N, etc.     one row per strain/sex/measure
• Tarantino1 supplementary data
Investigators Lisa M Tarantino       University of North Carolina,  Chapel Hill, NC
Tim Wiltshire       University of North Carolina,  Chapel Hill, NC
Participants Ervin RB, Duan H, Zamboni WC, Cook S, Chung W, Zou F
ContactLisa M Tarantino     lisat@med.unc.edu     Lab web site
AcknowledgementsFunding provided by NIH DA023690, DA028420
Project type Phenotype strain survey data set
MPD identifiersTarantino1     MPD:459
Data changelog No updates/corrections.       Initial release date: 08/2015.
Formatted citation
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Mice: inbred   45 strains   ♂   age 8-11wks   1 experimental group

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Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
Sample Size (Avg)
    Tarantino1 body weight (none) body weight on day 2   [g]  bw   45901     inbred 45 m 8-11wks N=18
    Tarantino1 open field test cocaine distance traveled, 30 min test   [cm]  dist   45911     baseline (day 2)    treated (day 3)    difference inbred 45 m 8-11wks N=18
    Tarantino1 open field test cocaine ambulatory episodes, 30 min test   [n]  amb_epi   45916     baseline (day 2)    treated (day 3)    difference inbred 45 m 8-11wks N=18
    Tarantino1 open field test cocaine rearing episodes, 30 min test   [n]  rear   45921     baseline (day 2)    treated (day 3)    difference inbred 45 m 8-11wks N=18
    Tarantino1 open field test cocaine average velocity, 30 min test   [cm/s]  vel   45926     baseline (day 2)    treated (day 3)    difference inbred 45 m 8-11wks N=18
    Tarantino1 open field test cocaine percentage of time resting, 30 min test   [%]  rest   45931     baseline (day 2)    treated (day 3)    difference inbred 45 m 8-11wks N=18
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