Tarantino1: Drug study: Initial locomotor sensitivity to cocaine in males of 45 inbred strains of mice (2015)

Wiltshire T, Ervin RB, Duan H, Bogue MA, Zamboni WC, Cook S, Chung W, Zou F, Tarantino LM. Initial locomotor sensitivity to cocaine varies widely among inbred mouse strains. Genes Brain Behav. 2015 Mar;14(3):271-80. doi: 10.1111/gbb.12209.   PubMed 25727211     FullText


       
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Participants Lisa M Tarantino       University of North Carolina Chapel Hill, NC
Tim Wiltshire       University of North Carolina Chapel Hill, NC
With: Ervin RB, Duan H, Zamboni WC, Cook S, Chung W, Zou F
ContactLisa M Tarantino     lisat@med.unc.edu     Lab web site
AcknowledgementsFunding provided by NIH DA023690, DA028420
Project type Phenotype strain survey data set
MPD identifiersTarantino1     MPD:459
Data changelog No updates/corrections.       Initial release date: 08/2015.
Formatted citation
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Summary of procedures that were conducted
• body weight
• open field test Locomotor activity. Baseline (saline) vs. cocaine i.p. 30 min test.
Mice: inbred   45 strains   ♂   age 8-11wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Tarantino1 45901 body weight (none) body weight on day 2   [g]  bw inbred 45 m 8-11wks N=18
    Tarantino1 45911 open field test cocaine distance traveled   [cm]     baseline    treated    difference inbred 45 m 8-11wks N=18
    Tarantino1 45916 open field test cocaine ambulatory episodes   [n]     baseline    treated    difference inbred 45 m 8-11wks N=18
    Tarantino1 45921 open field test cocaine rearing episodes   [n]     baseline    treated    difference inbred 45 m 8-11wks N=18
    Tarantino1 45926 open field test cocaine average velocity   [cm/s]     baseline    treated    difference inbred 45 m 8-11wks N=18
    Tarantino1 45931 open field test cocaine resting   [%]     baseline    treated    difference inbred 45 m 8-11wks N=18
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