Project measure / variable:   CSNA03   dist_d3_d2_cocaine_do

ID, description, units MPD:90309   dist_d3_d2_cocaine_do   distance traveled, last 60 min (post-injection), Day 3 (cocaine) minus Day 2 (saline), cocaine sensitization, DO   [cm]  
cocaine study
Data set, strains CSNA03   DO population w/par   9 strains     sex: both     age: 8-21wks
Procedure open field test
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means7669.0   cm 9420.0   cm
Median of the strain means5944.0   cm 9428.0   cm
SD of the strain means± 6493.0 ± 7021.0
Coefficient of variation (CV)0.8467 0.7453
Min–max range of strain means1295.0   –   21081.0   cm 170.8   –   19738.0   cm
Mean sample size per strain26.9   mice 27.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1148661209.8997 1148661209.8997 15.8348 < 0.0001
strain 8 4903610515.6943 612951314.4618 8.4498 < 0.0001
sex:strain 8 834160284.2744 104270035.5343 1.4374 0.1783
Residuals 472 34239117078.3886 72540502.2847


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3025.0 7279.0   6 2972.0 2.4066 -12.7, 17882.0 -0.72
129S1/SvImJ m 1762.0 1971.0   6 804.8 1.1188 -80.83, 5622.0 -1.09
A/J f 1295.0 2907.0   12 839.2 2.2446 -2656.0, 8556.0 -0.98
A/J m 170.8 917.7   11 276.7 5.3716 -1614.0, 1668.0 -1.32
C57BL/6J f 2917.0 860.2   5 384.7 0.2949 1958.0, 4181.0 -0.73
C57BL/6J m 5532.0 2978.0   6 1216.0 0.5383 2806.0, 11086.0 -0.55
CAST/EiJ f 15317.0 15350.0   6 6267.0 1.0022 -922.1, 42272.0 1.18
CAST/EiJ m 10418.0 8445.0   5 3777.0 0.8106 1358.0, 22148.0 0.14
J:DO f 5944.0 7951.0   185 584.6 1.3377 -6511.0, 38640.0 -0.27
J:DO m 9428.0 9416.0   191 681.3 0.9987 -3225.0, 42895.0 0.0
NOD/ShiLtJ f 6426.0 5870.0   6 2396.0 0.9136 378.6, 16752.0 -0.19
NOD/ShiLtJ m 13806.0 13296.0   6 5428.0 0.9631 -122.1, 38411.0 0.62
NZO/HlLtJ f 4653.0 2653.0   6 1083.0 0.5703 1587.0, 7735.0 -0.46
NZO/HlLtJ m 5055.0 5245.0   7 1982.0 1.0376 1295.0, 13198.0 -0.62
PWK/PhJ f 8359.0 9010.0   9 3003.0 1.0778 -845.0, 25100.0 0.11
PWK/PhJ m 19738.0 11605.0   9 3868.0 0.588 -2685.0, 34795.0 1.47
WSB/EiJ f 21081.0 8304.0   7 3139.0 0.3939 7111.0, 30795.0 2.07
WSB/EiJ m 18871.0 8832.0   7 3338.0 0.468 11225.0, 34135.0 1.35


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3024.595 3477.079768156 9857.0660507025 -3807.8760507024
129S1/SvImJ m 1761.9283333334 3477.0797681561 8594.3993840359 -5070.5427173692
A/J f 1295.05 2458.6666827896 6126.3366122124 -3536.2366122124
A/J m 170.836 2567.9935974984 5216.9502922246 -4875.2782922247
C57BL/6J f 2917.4 3808.9500465279 10401.9970359417 -4567.1970359417
C57BL/6J m 5531.9999999999 3477.0797681561 12364.4710507024 -1300.4710507026
CAST/EiJ f 15317.15 3477.0797681561 22149.6210507026 8484.6789492975
CAST/EiJ m 10417.6000000002 3808.9500465278 17902.1970359417 2933.0029640587
J:DO f 5943.787805027 626.1875303459 7174.2479781245 4713.3276319296
J:DO m 9427.9388376963 616.2736451278 10638.9181998062 8216.9594755864
NOD/ShiLtJ f 6425.6 3477.0797681561 13258.0710507025 -406.8710507025
NOD/ShiLtJ m 13806.4833333333 3477.0797681561 20638.9543840358 6974.0122826308
NZO/HlLtJ f 4652.6666666666 3477.0797681561 11485.1377173691 -2179.804384036
NZO/HlLtJ m 5055.0000000001 3219.1503378714 11380.6390298546 -1270.6390298544
PWK/PhJ f 8358.8444444444 2839.0237423124 13937.5336966307 2780.1551922582
PWK/PhJ m 19738.0 2839.0237423124 25316.6892521863 14159.3107478137
WSB/EiJ f 21081.2857142857 3219.1503378714 27406.9247441402 14755.6466844312
WSB/EiJ m 18871.0 3219.1503378714 25196.6390298545 12545.3609701455


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2393.2616666667 2458.6666827897 7224.5482788792 -2438.0249455458
A/J both 732.943 1777.6130747334 4225.9574495671 -2760.0714495671
C57BL/6J both 4224.7 2578.671371611 9291.7961469345 -842.3961469346
CAST/EiJ both 12867.3750000001 2578.671371611 17934.4711469346 7800.2788530656
J:DO both 7685.8633213617 439.2903449997 8549.0700250305 6822.6566176928
NOD/ShiLtJ both 10116.0416666667 2458.6666827897 14947.3282788792 5284.7550544541
NZO/HlLtJ both 4853.8333333333 2369.2304980699 9509.3776031987 198.2890634679
PWK/PhJ both 14048.4222222222 2007.4929401387 17993.1512225756 10103.6932218688
WSB/EiJ both 19976.1428571428 2276.2830335678 24449.0451104912 15503.2406037944




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA