Project measure / variable:   CSNA03   acquisition_do

ID, description, units MPD:110261   acquisition_do   number of sessions to acquisition (1.0 mg/kg) (intravenous self administration), DO   [n]  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age: 4-25wks
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means9.7313   n 9.2296   n
Median of the strain means9.1394   n 7.859   n
SD of the strain means± 2.5939 ± 2.6282
Coefficient of variation (CV)0.2665 0.2848
Min–max range of strain means6.4615   –   13.2   n 7.1818   –   14.125   n
Mean sample size per strain49.5   mice 45.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.5744 0.5744 0.0403 0.8409
strain 7 1042.7295 148.9614 10.4589 < 0.0001
sex:strain 7 71.2637 10.1805 0.7148 0.6595
Residuals 747 10639.1519 14.2425


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 12.667 7.2405   12 2.0901 0.5716 5.0, 28.0 1.13
A/J m 12.333 6.6895   9 2.2298 0.5424 5.0, 24.0 1.18
C57BL/6J f 12.077 7.6427   13 2.1197 0.6328 5.0, 27.0 0.9
C57BL/6J m 9.6154 4.9756   13 1.38 0.5175 5.0, 24.0 0.15
CAST/EiJ f 9.125 4.8237   8 1.7054 0.5286 5.0, 20.0 -0.23
CAST/EiJ m 7.5 1.0   4 0.5 0.1333 6.0, 8.0 -0.66
J:DO f 7.9844 3.2049   321 0.17888 0.4014 5.0, 28.0 -0.67
J:DO m 8.1623 3.5046   302 0.20167 0.4294 5.0, 26.0 -0.41
NOD/ShiLtJ f 9.1538 5.942   13 1.648 0.6491 5.0, 21.0 -0.22
NOD/ShiLtJ m 7.5556 2.0683   9 0.68943 0.2737 5.0, 11.0 -0.64
NZO/HlLtJ f 6.4615 2.367   13 0.65648 0.3663 5.0, 13.0 -1.26
NZO/HlLtJ m 7.1818 1.7215   11 0.51906 0.2397 5.0, 10.0 -0.78
PWK/PhJ f 7.1818 2.7502   11 0.82922 0.3829 5.0, 14.0 -0.98
PWK/PhJ m 7.3636 3.1709   11 0.95606 0.4306 5.0, 14.0 -0.71
WSB/EiJ f 13.2 9.0664   5 4.0546 0.6869 5.0, 27.0 1.34
WSB/EiJ m 14.125 8.4251   8 2.9787 0.5965 5.0, 27.0 1.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 12.6666666667 1.0894381555 14.8053914949 10.5279418384
A/J m 12.3333333333 1.2579748247 14.802920044 9.8637466227
C57BL/6J f 12.0769230769 1.0466983232 14.1317434264 10.0221027275
C57BL/6J m 9.6153846154 1.0466983232 11.6702049649 7.5605642659
CAST/EiJ f 9.125 1.3342837937 11.7443922647 6.5056077353
CAST/EiJ m 7.5 1.8869622371 11.2043800659 3.7956199341
J:DO f 7.984423676 0.2106399235 8.3979403423 7.5709070097
J:DO m 8.1622516556 0.2171649504 8.5885778944 7.7359254168
NOD/ShiLtJ f 9.1538461538 1.0466983232 11.2086665033 7.0990258044
NOD/ShiLtJ m 7.5555555556 1.2579748247 10.0251422662 5.0859688449
NZO/HlLtJ f 6.4615384615 1.0466983232 8.516358811 4.4067181121
NZO/HlLtJ m 7.1818181818 1.1378810425 9.4156434108 4.9479929528
PWK/PhJ f 7.1818181818 1.1378810425 9.4156434108 4.9479929528
PWK/PhJ m 7.3636363636 1.1378810425 9.5974615927 5.1298111346
WSB/EiJ f 13.2 1.6877503332 16.5132982568 9.8867017432
WSB/EiJ m 14.125 1.3342837937 16.7443922647 11.5056077353


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 12.5 0.8320721355 14.1334780694 10.8665219306
C57BL/6J both 10.8461538462 0.7401274822 12.2991312494 9.3931764429
CAST/EiJ both 8.3125 1.1555236612 10.5809602437 6.0440397563
J:DO both 8.0733376658 0.1512694558 8.3703015084 7.7763738232
NOD/ShiLtJ both 8.3547008547 0.8182417185 9.9610278132 6.7483738962
NZO/HlLtJ both 6.8216783217 0.7730379432 8.3392637247 5.3040929186
PWK/PhJ both 7.2727272727 0.8046034014 8.8522802402 5.6931743053
WSB/EiJ both 13.6625 1.0757339854 15.7743215582 11.5506784418




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA