MPD: Project measures / variables set: Jentsch2 discrimination

Project measures / variables set: Jentsch2 discrimination_FR5

ID, description, units	MPD:49726 discrimination_FR5 Fixed ratio 5 - discrimination index between active and inactive levers [%] cocaine study
Measures	• day 1 • day 3 • day 5
Data set, strains	Jentsch2 BXD 4 strains sex: both age: 8-17wks
Procedure	operant conditioning chamber
Comparison	repeated measures, set of trials, same cohort
Ontology mappings	VT:0002063 learning/memory/conditioning trait VT:0010473 impulsivity behavior trait VT:0010531 operant conditioning behavior trait VT:0010718 response to cocaine trait MP:0001988 cocaine preference MP:0002803 abnormal operant conditioning behavior MP:0010698 abnormal impulsive behavior control MP:0020158 abnormal behavioral response to cocaine

Values Means Δ Means Z-scores

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Jentsch2 - Fixed ratio 5 - discrimination index between active and inactive levers

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between sex	1	112.2071	112.2071	4.5424	0.0471
between strain	1	8.8792	8.8792	0.3595	0.5563
between sex:strain	1	17.6381	17.6381	0.714	0.4092
between Residuals	18	444.6364	24.702
within group	2	104.9169	52.4584	2.4319	0.1022
within group:sex	2	114.2093	57.1046	2.6473	0.0846
within group:strain	2	8.9667	4.4834	0.2078	0.8133
within group:sex:strain	2	5.3726	2.6863	0.1245	0.8833
within Residuals	36	776.5642	21.5712

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Jentsch2	49726	operant conditioning chamber	cocaine	Fixed ratio 5 - discrimination index between active and inactive levers [%] day 1 discrimination1_FR5	BXD	4	both	8-17wks
Jentsch2	49727	operant conditioning chamber	cocaine	Fixed ratio 5 - discrimination index between active and inactive levers [%] day 3 discrimination3_FR5	BXD	4	both	8-17wks
Jentsch2	49728	operant conditioning chamber	cocaine	Fixed ratio 5 - discrimination index between active and inactive levers [%] day 5 discrimination5_FR5	BXD	4	both	8-17wks