Project measure / variable:   CSNA03   dist_d3_d11_auc_cocaine_do

ID, description, units MPD:90442   dist_d3_d11_auc_cocaine_do   distance traveled, last 60 min (post-injection), Day 3 (cocaine) to Day 11 (cocaine) AUC, cocaine sensitization, DO    
cocaine study
Data set, strains CSNA03   DO population w/par   9 strains     sex: both     age: 8-21wks
Procedure open field test
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means178888.0   None 167098.0   None
Median of the strain means145547.0   None 177624.0   None
SD of the strain means± 124226.0 ± 109712.0
Coefficient of variation (CV)0.6944 0.6566
Min–max range of strain means20635.0   –   353588.0   None 19898.0   –   314526.0   None
Mean sample size per strain20.6   mice 21.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 21919966609.8169 21919966609.8169 2.3372 0.1272
strain 8 1638451592786.3123 204806449098.289 21.8372 < 0.0001
sex:strain 8 99584709737.8653 12448088717.2332 1.3273 0.2285
Residuals 359 3366985813779.6475 9378790567.6313


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 52027.0 124071.0   6 50652.0 2.3847 -1.02
129S1/SvImJ m 19898.0 19568.0   6 7989.0 0.9835 2749.0, 52297.0 -1.34
A/J f 20635.0 12103.0   11 3649.0 0.5865 4334.0, 38769.0 -1.27
A/J m 24299.0 22446.0   12 6480.0 0.9238 3129.0, 85285.0 -1.3
C57BL/6J f 127391.0 12478.0   4 6239.0 0.0979 113104.0, 143527.0 -0.41
C57BL/6J m 152955.0 52922.0   7 20003.0 0.346 80072.0, 221508.0 -0.13
CAST/EiJ f 330854.0 114097.0   6 46580.0 0.3449 219795.0, 499672.0 1.22
CAST/EiJ m 268513.0 91452.0   5 40899.0 0.3406 146860.0, 383331.0 0.92
J:DO f 145547.0 101607.0   131 8877.0 0.6981 4680.0, 455273.0 -0.27
J:DO m 177624.0 108708.0   133 9426.0 0.612 8434.0, 561227.0 0.1
NOD/ShiLtJ f 222592.0 66985.0   6 27347.0 0.3009 139095.0, 304487.0 0.35
NOD/ShiLtJ m 239615.0 88130.0   6 35979.0 0.3678 112667.0, 339006.0 0.66
NZO/HlLtJ f 71368.0 30963.0   5 13847.0 0.4338 41586.0, 110600.0 -0.87
NZO/HlLtJ m 63057.0 30310.0   7 11456.0 0.4807 27941.0, 112161.0 -0.95
PWK/PhJ f 285992.0 43181.0   9 14394.0 0.151 234836.0, 353765.0 0.86
PWK/PhJ m 314526.0 88481.0   9 29494.0 0.2813 200266.0, 468118.0 1.34
WSB/EiJ f 353588.0 118553.0   7 44809.0 0.3353 207780.0, 564783.0 1.41
WSB/EiJ m 243392.0 71604.0   7 27064.0 0.2942 121817.0, 335425.0 0.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 52027.0383333326 39536.4611627278 129779.2031767622 -25725.1265100969
129S1/SvImJ m 19897.4999999995 39536.4611627278 97649.6648434291 -57854.6648434301
A/J f 20634.7272727271 29199.6117153999 78058.5066574187 -36789.0521119645
A/J m 24298.8333333329 27956.4997922834 79277.9163460562 -30680.2496793904
C57BL/6J f 127391.0000000002 48422.0780420234 222617.5651315835 32164.4348684169
C57BL/6J m 152954.5714285719 36603.6504183305 224939.0884414483 80970.0544156956
CAST/EiJ f 330853.8333333327 39536.461162728 408605.9981767626 253101.6684899029
CAST/EiJ m 268513.3999999992 43310.0232455059 353686.6291592122 183340.1708407862
J:DO f 145546.5954198472 8461.3132034547 162186.5626713194 128906.6281683749
J:DO m 177623.8796992479 8397.4533230627 194138.2604970747 161109.4989014211
NOD/ShiLtJ f 222592.4999999999 39536.4611627279 300344.6648434296 144840.3351565702
NOD/ShiLtJ m 239614.8333333332 39536.4611627278 317366.9981767628 161862.6684899036
NZO/HlLtJ f 71368.3999999971 43310.0232455061 156541.6291592105 -13804.8291592163
NZO/HlLtJ m 63056.9999999998 36603.6504183303 135041.5170128758 -8927.5170128761
PWK/PhJ f 285992.1111111109 32281.3853613491 349476.4878655002 222507.7343567217
PWK/PhJ m 314525.9999999998 32281.3853613491 378010.3767543891 251041.6232456105
WSB/EiJ f 353588.4285714284 36603.6504183303 425572.9455843043 281603.9115585525
WSB/EiJ m 243392.1428571428 36603.6504183303 315376.6598700187 171407.6258442669


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 35962.2691666661 27956.4997922834 90941.3521793893 -19016.8138460572
A/J both 22466.78030303 20212.515955257 62216.591647682 -17283.031041622
C57BL/6J both 140172.785714286 30350.1435987342 199859.1941259519 80486.3773026202
CAST/EiJ both 299683.6166666659 29321.0243460138 357346.1653946914 242021.0679386405
J:DO both 161585.2375595475 5960.5168282619 173307.1538199729 149863.3212991222
NOD/ShiLtJ both 231103.6666666666 27956.4997922834 286082.7496793899 176124.5836539432
NZO/HlLtJ both 67212.6999999985 28353.0656961184 122971.6671151292 11453.7328848677
PWK/PhJ both 300259.0555555553 22826.3864951061 345149.2888579856 255368.8222531251
WSB/EiJ both 298490.2857142856 25882.6894269832 349391.0258345285 247589.5455940426




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA