Dickson2: Novelty-related behaviors and intravenous cocaine self-administration in a Diversity Outbred (DO) mouse population (2015)

Dickson PE, Ndukum J, Wilcox T, Clark J, Roy B, Zhang L, Li Y, Lin DT, Chesler EJ. Association of novelty-related behaviors and intravenous cocaine self-administration in Diversity Outbred mice. Psychopharmacology (Berl). 2015 Mar;232(6):1011-24. doi: 10.1007/s00213-014-3737-5. Epub 2014 Sep 20.   PubMed 25238945     FullText


       
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Participants Price E Dickson       The Jackson Laboratory Bar Harbor, ME
Elissa J Chesler       The Jackson Laboratory Bar Harbor, ME
With: Ndukum J, Wilcox T, Clark J, Roy B, Zhang L, Li Y, Lin D-T
ContactPrice E Dickson     price.dickson@jax.org
AcknowledgementsFunding provided by NIH CA034196, GM076468; acknowledge support from NIDA Drug Supply Program
Project type Phenotype strain survey data set
MPD identifiersDickson2     MPD:548
Data changelog No updates/corrections.       Initial release date: 06/2016.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
FR = fixed ratio; PR = progressive ratio;

Summary of procedures that were conducted
• open field test Locomotor activity and exploratory behavior. 20 min test.
• hole board test Exploratory behavior. 10 min test.
• monitoring system Novelty preference test (preference for novel side vs. familiar side). 10 min test.
• operant conditioning chamber Intravenous self-administration of cocaine via activation of levers.
Mice: DO population   ♀♂   age 12-16wks   1 cohort