MPD: Phenotype measures mapped to VT:0001560, blood insulin amount

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Attie2:80	Attie2	hormone quantification	high-fat high-sucrose diet	plasma insulin after diet (4h fast) [ng/mL] INS 110697 wk: 6 10 14 22	DO population		both	10-26wks	N=250	2018

Attie2:90	Attie2	glucose tolerance	high-fat high-sucrose diet	insulin level at t=0 after ~14 wks on diet (4h fast) [ng/mL] INS_0min 110707	DO population		both	18wks	N=248	2018

Attie2:91	Attie2	glucose tolerance	high-fat high-sucrose diet	HOMA-IR: (glucose x insulin) / 405 at t=0 after ~14 wks on diet (4h fast) HOMA_IR 110708	DO population		both	18wks	N=248	2018

Attie2:92	Attie2	glucose tolerance	high-fat high-sucrose diet	HOMA-B: (360 x insulin) / (glucose minus 63) at t=0 after ~14 wks on diet (4h fast) HOMA_B 110709	DO population		both	18wks	N=246	2018

Attie2:95	Attie2	glucose tolerance	high-fat high-sucrose diet	insulin area under curve (AUC) after ~14 wks on diet without correction for baseline difference (4h fast) [AUC] INS_AUC_tot 110712	DO population		both	18wks	N=248	2018

Attie2:96	Attie2	glucose tolerance	high-fat high-sucrose diet	insulin area under curve (AUC) after ~14 wks on diet after subtraction of insulin at t=0 (4h fast) [AUC] INS_AUC_adj 110713	DO population		both	18wks	N=248	2018

Auwerx1:85	Auwerx1	hormone quantification	high-fat diet	insulin baseline, glucose tolerance test (pregavage, overnight fast) [µg/L] ogtt_ins_t0 111264 CD HFD	BXD w/par	57	m	17wks	N=4	2016

Auwerx1:87	Auwerx1	hormone quantification	high-fat diet	insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min [µg/L] ogtt_ins_t15 111266 CD HFD	BXD w/par	57	m	17wks	N=4	2016

Auwerx1:89	Auwerx1	hormone quantification	high-fat diet	insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min [µg/L] ogtt_ins_t30 111268 CD HFD	BXD w/par	57	m	17wks	N=4	2016

Auwerx1:91	Auwerx1	hormone quantification	high-fat diet	insulin, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast) [AUC] ogtt_ins_auc 111270 CD HFD	BXD w/par	57	m	17wks	N=4	2016

Auwerx2:73	Auwerx2	hormone quantification	(none)	insulin baseline, glucose tolerance test (pregavage, overnight fast) [µg/L] ogtt_ins_t0 114601 CD HFD	inbred w/CC8	9	both	16wks	N=4	2021

Auwerx2:75	Auwerx2	hormone quantification	(none)	insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min [µg/L] ogtt_ins_t15 114603 CD HFD	inbred w/CC8	8	both	16wks	N=4	2021

Auwerx2:77	Auwerx2	hormone quantification	(none)	insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min [µg/L] ogtt_ins_t30 114605 CD HFD	inbred w/CC8	8	both	16wks	N=4	2021

Bennett4:93	Bennett4	hormone quantification	various diets 2	plasma insulin amount, baseline [ng/mL] INS_base 114787 diet: HP group HFHS group	CC	22	f	8-11wks	N=5	2021

Bennett4:95	Bennett4	hormone quantification	various diets 2	plasma insulin amount, post-diet [ng/mL] INS_post 114789 diet: HP group HFHS group	CC	22	f	17-20wks	N=4	2021

Bennett4:97	Bennett4	hormone quantification	various diets 2	plasma glucose to insulin ratio, baseline [ratio] GLU_INS_base 114791 diet: HP group HFHS group	CC	22	f	8-11wks	N=5	2021

Bennett4:99	Bennett4	hormone quantification	various diets 2	plasma glucose to insulin ratio, post-diet [ratio] GLU_INS_post 114793 diet: HP group HFHS group	CC	22	f	17-20wks	N=4	2021

Brockmann1:30	Brockmann1	hormone quantification	(none)	insulin level [pmol/L] insulin 21510	QTL population		both	6wks	N=201	2009

Brockmann1:33	Brockmann1	hormone quantification	(none)	insulin level, log10 transformed [log(pmol/L)] lg_ins 21513	QTL population		both	6wks	N=201	2009

Cheverud1:45	Cheverud1	hormone quantification	high-fat diet	insulin (serum) [ng/mL] insulin 17840 control diet high-fat diet	LGXSM w/par	17	both	20-30wks	N=8	2004

JaxCC1:9201	JaxCC1	hormone quantification	(none)	insulin (plasma) [pg/mL] insulin 89201	CC	18	both	17-19wks	N=6	2017

JaxKOMP-EAP:445	JaxKOMP-EAP	hormone quantification	(none)	insulin (plasma) [pg/mL] insulin 100637	KOMP	410	both	18wks	N=14	2016

Kim1:3	Kim1	hormone quantification	(none)	non-fasted insulin level [ng/mL] Insulin 11403	QTL population		m	26wks	N=206	2001

Leiter2:17	Leiter2	hormone quantification	(none)	insulin in plasma [ng/mL] Insulin 24017	QTL population		f	14-40wks	N=310	2009

Nadeau2:7	Nadeau2	hormone quantification	high-fat high-sucrose diet	insulin (plasma, 16h fast) [pmol/L] INS 53022	B6.A consomic w/par	24	m	21wks	N=39	2015

Nadeau2:8	Nadeau2	hormone quantification	high-fat high-sucrose diet	homeostasis model assessment insulin resistance (HOMA-IR, 16h fast) HOMA_IR 53023	B6.A consomic w/par	24	m	21wks	N=39	2015

Nadeau3:7	Nadeau3	hormone quantification	high-fat high-sucrose diet	insulin amount (overnight fast) after 16 wks on diet [pmol/L] INS 114350 chow HFHS	inbred	2	m	21wks	N=17	2016

Nadeau3:9	Nadeau3	hormone quantification	high-fat high-sucrose diet	homeostasis model assessment insulin resistance (overnight fast) after 16 wks on diet [] HOMA_IR 114352 chow HFHS	inbred	2	m	21wks	N=17	2016

Naggert1:5	Naggert1	hormone quantification	high-fat diet	insulin [ng/mL] INS_fat18 14305	inbred w/CC7	43	both	25-27wks	N=12	2003

Reifsnyder1:13	Reifsnyder1	hormone quantification	(none)	insulin (plasma), 16 wks [ng/mL] INS_16 11113	QTL population		m	16wks	N=204	2000

Reifsnyder1:14	Reifsnyder1	hormone quantification	(none)	insulin (plasma), 20 wks [ng/mL] INS_20 11114	QTL population		m	20wks	N=204	2000

Reifsnyder1:15	Reifsnyder1	hormone quantification	(none)	insulin (plasma), 24 wks [ng/mL] INS_24 11115	QTL population		m	24wks	N=204	2000

Reifsnyder1:16	Reifsnyder1	hormone quantification	(none)	leptin, 24 wks [ng/mL] LEP_24 11116	QTL population		m	24wks	N=204	2000

Schonfeld1:8	Schonfeld1	hormone quantification	(none)	insulin level (plasma), 30 min post injection in glucose tolerance test (10% glucose i.p., 5h fast) [ng/mL] Insulin 32311	inbred	10	both	9-13wks	N=5	2005

Xenakis2:226	Xenakis2	hormone quantification	arsenic	fasting plasma insulin (6h fast) [ng/mL] FPI 118380 iAs: 1 wk before 4 wks after 8 wks after 13 wks after 16 wks after 20 wks after 25 wks after	DO population		m	7-33wks	N=71	2022

Xenakis2:233	Xenakis2	hormone quantification	arsenic	plasma insulin, 15 min after intraperitoneal (i.p. 0.2% glucose, 6h fast) injection [ng/mL] PI15 118387 iAs: 1 wk before 13 wks after 25 wks after	DO population		m	7-33wks	N=72	2022

Xenakis2:236	Xenakis2	hormone quantification	arsenic	fasting plasma insulin (6h fast), coefficient of variation (CV) [%] FPI_CV 118390 iAs: 1wk before 4 wks after 8 wks after 13 wks after 16 wks after 20 wks after 25 wks after	DO population		m	7-33wks	N=73	2022

Xenakis2:243	Xenakis2	hormone quantification	arsenic	plasma insulin, 15 min after intraperitoneal (i.p. 0.2% glucose, 6h fast) injection, coefficient of variation (CV) [%] PI15_CV 118397 iAs: 1wk before 13 wks after 25 wks after	DO population		m	7-33wks	N=72	2022

Attie2

hormone quantification

high-fat high-sucrose diet

plasma insulin after diet (4h fast) [ng/mL] INS 110697 wk: 6 10 14 22

DO population

both

10-26wks

N=250

2018

Attie2

glucose tolerance

high-fat high-sucrose diet

insulin level at t=0 after ~14 wks on diet (4h fast) [ng/mL] INS_0min 110707

DO population

both

18wks

N=248

2018

Attie2

glucose tolerance

high-fat high-sucrose diet

HOMA-IR: (glucose x insulin) / 405 at t=0 after ~14 wks on diet (4h fast) HOMA_IR 110708

DO population

both

18wks

N=248

2018

Attie2

glucose tolerance

high-fat high-sucrose diet

HOMA-B: (360 x insulin) / (glucose minus 63) at t=0 after ~14 wks on diet (4h fast) HOMA_B 110709

DO population

both

18wks

N=246

2018

Attie2

glucose tolerance

high-fat high-sucrose diet

insulin area under curve (AUC) after ~14 wks on diet without correction for baseline difference (4h fast) [AUC] INS_AUC_tot 110712

DO population

both

18wks

N=248

2018

Attie2

glucose tolerance

high-fat high-sucrose diet

insulin area under curve (AUC) after ~14 wks on diet after subtraction of insulin at t=0 (4h fast) [AUC] INS_AUC_adj 110713

DO population

both

18wks

N=248

2018

Auwerx1

hormone quantification

high-fat diet

insulin baseline, glucose tolerance test (pregavage, overnight fast) [µg/L] ogtt_ins_t0 111264 CD HFD

BXD w/par

57

m

17wks

N=4

2016

Auwerx1

hormone quantification

high-fat diet

insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min [µg/L] ogtt_ins_t15 111266 CD HFD

BXD w/par

57

m

17wks

N=4

2016

Auwerx1

hormone quantification

high-fat diet

insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min [µg/L] ogtt_ins_t30 111268 CD HFD

BXD w/par

57

m

17wks

N=4

2016

Auwerx1

hormone quantification

high-fat diet

insulin, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast) [AUC] ogtt_ins_auc 111270 CD HFD

BXD w/par

57

m

17wks

N=4

2016

Auwerx2

hormone quantification

(none)

insulin baseline, glucose tolerance test (pregavage, overnight fast) [µg/L] ogtt_ins_t0 114601 CD HFD

inbred w/CC8

9

both

16wks

N=4

2021

Auwerx2

hormone quantification

(none)

insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min [µg/L] ogtt_ins_t15 114603 CD HFD

inbred w/CC8

8

both

16wks

N=4

2021

Auwerx2

hormone quantification

(none)

insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min [µg/L] ogtt_ins_t30 114605 CD HFD

inbred w/CC8

8

both

16wks

N=4

2021

Bennett4

hormone quantification

various diets 2

plasma insulin amount, baseline [ng/mL] INS_base 114787 diet: HP group HFHS group

CC

22

f

8-11wks

N=5

2021

Bennett4

hormone quantification

various diets 2

plasma insulin amount, post-diet [ng/mL] INS_post 114789 diet: HP group HFHS group

CC

22

f

17-20wks

N=4

2021

Bennett4

hormone quantification

various diets 2

plasma glucose to insulin ratio, baseline [ratio] GLU_INS_base 114791 diet: HP group HFHS group

CC

22

f

8-11wks

N=5

2021

Bennett4

hormone quantification

various diets 2

plasma glucose to insulin ratio, post-diet [ratio] GLU_INS_post 114793 diet: HP group HFHS group

CC

22

f

17-20wks

N=4

2021

Brockmann1

hormone quantification

(none)

insulin level [pmol/L] insulin 21510

QTL population

both

6wks

N=201

2009

Brockmann1

hormone quantification

(none)

insulin level, log10 transformed [log(pmol/L)] lg_ins 21513

QTL population

both

6wks

N=201

2009

Cheverud1

hormone quantification

high-fat diet

insulin (serum) [ng/mL] insulin 17840 control diet high-fat diet

LGXSM w/par

17

both

20-30wks

N=8

2004

JaxCC1

hormone quantification

(none)

insulin (plasma) [pg/mL] insulin 89201

CC

18

both

17-19wks

N=6

2017

JaxKOMP-EAP

hormone quantification

(none)

insulin (plasma) [pg/mL] insulin 100637

KOMP

410

both

18wks

N=14

2016

Kim1

hormone quantification

(none)

non-fasted insulin level [ng/mL] Insulin 11403

QTL population

m

26wks

N=206

2001

Leiter2

hormone quantification

(none)

insulin in plasma [ng/mL] Insulin 24017

QTL population

f

14-40wks

N=310

2009

Nadeau2

hormone quantification

high-fat high-sucrose diet

insulin (plasma, 16h fast) [pmol/L] INS 53022

B6.A consomic w/par

24

m

21wks

N=39

2015

Nadeau2

hormone quantification

high-fat high-sucrose diet

homeostasis model assessment insulin resistance (HOMA-IR, 16h fast) HOMA_IR 53023

B6.A consomic w/par

24

m

21wks

N=39

2015

Nadeau3

hormone quantification

high-fat high-sucrose diet

insulin amount (overnight fast) after 16 wks on diet [pmol/L] INS 114350 chow HFHS

inbred

2

m

21wks

N=17

2016

Nadeau3

hormone quantification

high-fat high-sucrose diet

homeostasis model assessment insulin resistance (overnight fast) after 16 wks on diet [] HOMA_IR 114352 chow HFHS

inbred

2

m

21wks

N=17

2016

Naggert1

hormone quantification

high-fat diet

insulin [ng/mL] INS_fat18 14305

inbred w/CC7

43

both

25-27wks

N=12

2003

Reifsnyder1

hormone quantification

(none)

insulin (plasma), 16 wks [ng/mL] INS_16 11113

QTL population

m

16wks

N=204

2000

Reifsnyder1

hormone quantification

(none)

insulin (plasma), 20 wks [ng/mL] INS_20 11114

QTL population

m

20wks

N=204

2000

Reifsnyder1

hormone quantification

(none)

insulin (plasma), 24 wks [ng/mL] INS_24 11115

QTL population

m

24wks

N=204

2000

Reifsnyder1

hormone quantification

(none)

leptin, 24 wks [ng/mL] LEP_24 11116

QTL population

m

24wks

N=204

2000

Schonfeld1

hormone quantification

(none)

insulin level (plasma), 30 min post injection in glucose tolerance test (10% glucose i.p., 5h fast) [ng/mL] Insulin 32311

inbred

10

both

9-13wks

N=5

2005

Xenakis2

hormone quantification

arsenic

fasting plasma insulin (6h fast) [ng/mL] FPI 118380 iAs: 1 wk before 4 wks after 8 wks after 13 wks after 16 wks after 20 wks after 25 wks after

DO population

m

7-33wks

N=71

2022

Xenakis2

hormone quantification

arsenic

plasma insulin, 15 min after intraperitoneal (i.p. 0.2% glucose, 6h fast) injection [ng/mL] PI15 118387 iAs: 1 wk before 13 wks after 25 wks after

DO population

m

7-33wks

N=72

2022

Xenakis2

hormone quantification

arsenic

fasting plasma insulin (6h fast), coefficient of variation (CV) [%] FPI_CV 118390 iAs: 1wk before 4 wks after 8 wks after 13 wks after 16 wks after 20 wks after 25 wks after

DO population

m

7-33wks

N=73

2022

Xenakis2

hormone quantification

arsenic

plasma insulin, 15 min after intraperitoneal (i.p. 0.2% glucose, 6h fast) injection, coefficient of variation (CV) [%] PI15_CV 118397 iAs: 1wk before 13 wks after 25 wks after

DO population

m

7-33wks

N=72

2022

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