MPD: Measures involving nociception assay

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Chesler1:1	Chesler1	nociception assay	(none)	latency of nociception to mechanical pressure on the tail [s] TC 34801	BXD	61	both	7-15wks	N=7	2010

Chesler1:10	Chesler1	nociception assay	(none)	mean sensory threshold eliciting withdrawal response from both hindfeet, Von Frey test days 1 and 2 [mN] VF 34810	BXD	61	both	7-15wks	N=6	2010

Chesler1:19	Chesler1	nociception assay	(none)	mean latency of both hindpaws to withdraw, Hargreaves test trials 1-3 [s] mean_HT 34819	BXD	61	both	7-15wks	N=6	2010

Chesler1:23	Chesler1	nociception assay	(none)	mean latency of tail withdrawal to thermal stimulation (trials 1, 2, 3) [s] mean_TW 34823	BXD	61	both	7-15wks	N=7	2010

Chesler1:29	Chesler1	nociception assay	(none)	mean latency of nociceptive response to hot plate (transformed) [s] mean_logN_HP 34829	BXD	61	both	7-15wks	N=6	2010

Chesler2:53	Chesler2	nociception assay	(none)	latency of nociceptive response to pressure on the tail, 60 s test [s] tail_clip 43473	CC diallel w/par	56	both	7-15wks	N=3	2011

Chesler2:54	Chesler2	nociception assay	(none)	latency of nociceptive response to hot plate (54°C), 30 s test [s] hot_plate 43474	CC diallel w/par	56	both	7-15wks	N=3	2011

Chesler3:73	Chesler3	nociception assay	(none)	latency of nociceptive response to pressure on the tail, 60 s test [s] tail_clip 43573	CC pre w/par	330	both	7-15wks	N=2	2011

Chesler3:74	Chesler3	nociception assay	(none)	latency of nociceptive response to hot plate (54°C), 30 s test [s] hot_plate 43574	CC pre w/par	329	both	7-15wks	N=2	2011

Chesler4:24	Chesler4	nociception assay	(none)	latency of hindpaw withdrawal, 55°C heat stimulation [s] HP_latency 47024	DO population w/par	9	both	12-16wks	N=8	2013

GMC07:11	GMC07	nociception assay	(none)	latency of nociceptive response to hot plate [s] latency 55611 reaction1 reaction2	inbred w/CC8	8	both	11-12wks	N=17	2018

GMC07:21	GMC07	nociception assay	(none)	type of response to hot plate, first reaction (0=no reaction, 1=shake, 2=lick, 3=jump, 4=other) [designation] response_1 55621	inbred w/CC8	8	both	11-12wks	N=17	2018

GMC07:22	GMC07	nociception assay	(none)	type of response to hot plate, second reaction (0=no reaction, 1=shake, 2=lick, 3=jump, 4=other) [designation] response_2 55622	inbred w/CC8	8	both	11-12wks	N=17	2018

Jaxwest1:23	Jaxwest1	nociception assay	(none)	hot plate test, latency to respond [s] HP 15123	inbred	7	both	9-12wks	N=8	2003

Jaxwest1:24	Jaxwest1	nociception assay	(none)	hot plate test, hindpaw response (0=flick; 1=lick) [score] HP_response 15124	inbred	7	both	9-12wks	N=8	2003

Koide1:8	Koide1	nociception assay	(none)	tail flick test: latency to respond [s] TF 1808	wild-derived Mishima	11	f	8-13wks	N=10	2000

Koide1:9	Koide1	nociception assay	(none)	hot plate test: latency to respond by licking [s] HP_LICK 1809	wild-derived Mishima	11	f	8-13wks	N=10	2000

Koide1:10	Koide1	nociception assay	(none)	hot plate test: latency to respond by jumping [s] HP_JUMP 1810	wild-derived Mishima	11	f	8-13wks	N=10	2000

Koide2:2	Koide2	nociception assay	(none)	capsaicin solution consumption, percentage of baseline [%] capsaicin 35802 concentration (µM): 0.5 1 4 7 10 15	wild-derived Mishima	14	both	8-12wks	N=10	2003

Mogil1:1	Mogil1	nociception assay	(none)	latency of nociceptive response, (53°C) hot plate test [s] HP 2201	inbred	11	m	6-18wks	N=8	2002

Mogil1:2	Mogil1	nociception assay	(none)	latency of heated hindpaw withdrawal, Hargreaves test [s] HT 2202	inbred	11	m	6-18wks	N=6	2002

Mogil1:3	Mogil1	nociception assay	(none)	latency of tail withdrawal, 49°C heat stimulation [s] TW_HOT1 2203	inbred	11	m	6-18wks	N=10	2002

Mogil1:4	Mogil1	nociception assay	(none)	median 50% foot withdrawal threshold, Von Frey test [mN] VF 2204	inbred	11	m	6-18wks	N=7	2002

Mogil1:5	Mogil1	nociception assay	(none)	number of abdominal constrictions induced with acetic acid (i.p.), 20 min [n] AC_AA 2205	inbred	11	m	6-18wks	N=6	2002

Mogil1:6	Mogil1	nociception assay	(none)	number of abdominal constrictions induced with magnesium sulfate (i.p.), 5 min [n] AC_MS 2206	inbred	11	m	6-18wks	N=6	2002

Mogil1:7	Mogil1	nociception assay	(none)	percent hypersensitivity threshold to carrageenan-induced thermal hyperalgesia, treated and heated hindpaw withdrawal [%] CAR_HT 2207	inbred	11	m	6-18wks	N=6	2002

Mogil1:8	Mogil1	nociception assay	(none)	duration of nociceptive response to acute inflammation (early phase), 0-10 min post-formalin (s.q.) injection [s] F_early 2208	inbred	11	m	6-18wks	N=7	2002

Mogil1:9	Mogil1	nociception assay	(none)	duration of nociceptive response to subacute/chronic inflammation (late phase), 10-60 min post-formalin (s.q.) injection [s] F_late 2209	inbred	11	m	6-18wks	N=7	2002

Mogil1:10	Mogil1	nociception assay	(none)	autotomy (neuropathy) score (1-11) following hindlimb denervation [score] AUT 2210	inbred	11	m	6-18wks	N=9	2002

Mogil1:11	Mogil1	nociception assay	(none)	percent hypersensitivity threshold to Hargreaves test following peripheral nerve injury (PNI) [%] PNI_HT 2211	inbred	11	m	6-18wks	N=6	2002

Mogil1:12	Mogil1	nociception assay	(none)	median 50% foot withdrawal hypersensitivity threshold to von Frey test following peripheral nerve injury (PNI) [mN] PNI_VF 2212	inbred	11	m	6-18wks	N=7	2002

Mogil1:20	Mogil1	nociception assay	(none)	duration of nociceptive response to capsaicin [s] CAP 2220	inbred	12	m	6-18wks	N=5	2002

Mogil1:21	Mogil1	nociception assay	(none)	duration of nociceptive response to bee venom [s] BV 2221	inbred	12	m	6-18wks	N=5	2002

Mogil1:22	Mogil1	nociception assay	(none)	latency of nociception to heated tail following hindleg acupuncture needles stimulation (analgesia), tail flick test [s] TF 2222	inbred	10	m	6-18wks	N=21	2002

Mogil1:23	Mogil1	nociception assay	(none)	latency of tail withdrawal, 47°C heat stimulation [s] TW_HOT2 2223	inbred	12	m	6-18wks	N=5	2002

Mogil1:24	Mogil1	nociception assay	(none)	latency of tail withdrawal, -15°C cold stimulation [s] TW_COLD 2224	inbred	12	m	6-18wks	N=5	2002

Mogil1:25	Mogil1	nociception assay	(none)	percent hypersensitivity threshold to capsaicin-induced thermal hyperalgesia, tail withdrawal at 47°C [%] CAP_TW 2225	inbred	12	m	6-18wks	N=5	2002

Mogil1:26	Mogil1	nociception assay	(none)	percent hypersensitivity threshold to bee venom-induced thermal hyperalgesia (ipsilateral), treated and heated hindpaw withdrawal [%] BV_HT 2226	inbred	12	m	6-18wks	N=5	2002

Mogil1:27	Mogil1	nociception assay	(none)	percent hypersensitivity threshold to bee venom-induced thermal hyperalgesia (contralateral), untreated and heated hindpaw withdrawal [%] BV_HT_CON 2227	inbred	12	m	6-18wks	N=5	2002

Mogil1:28	Mogil1	nociception assay	(none)	latency of nociception to pinched tail [s] TC 2228	inbred	12	m	6-18wks	N=7	2002

Mogil1:29	Mogil1	nociception assay	(none)	percent hypersensitivity threshold to mechanical stimulation following dynorphin treatment, von Frey test [%] DYN_VF 2229	inbred	7	m	6-18wks	N=4	2002

Mogil3:1	Mogil3	nociception assay	(none)	50% hindpaw withdrawal threshold, von Frey test [g] baseline 48001	inbred	18	both	7-12wks	N=3	2012

Mogil3:2	Mogil3	nociception assay	(none)	percentage of maximum hindpaw mechanical allodynia over 28 days after spared nerve injury [%] allodynia 48002	inbred	18	both	7-12wks	N=3	2012

Recla1:1	Recla1	nociception assay	(none)	time to respond to heat [s] latency_to_respond 28501	DO population		both	13-17wks	N=130	2013

Recla2:1	Recla2	nociception assay	(none)	wound licking or biting 11-60 min after formalin injection (chronic response) [score] formalin_score 62701	DO population		both	13-17wks	N=138	2018

Recla2:2	Recla2	nociception assay	(none)	wound licking or biting 11-60 min after formalin injection (chronic response), square root [sqrt(score)] formalin_score_sqrt 62702	DO population		both	13-17wks	N=138	2018

Chesler1

nociception assay

(none)

latency of nociception to mechanical pressure on the tail [s] TC 34801

BXD

61

both

7-15wks

N=7

2010

Chesler1

nociception assay

(none)

mean sensory threshold eliciting withdrawal response from both hindfeet, Von Frey test days 1 and 2 [mN] VF 34810

BXD

61

both

7-15wks

N=6

2010

Chesler1

nociception assay

(none)

mean latency of both hindpaws to withdraw, Hargreaves test trials 1-3 [s] mean_HT 34819

BXD

61

both

7-15wks

N=6

2010

Chesler1

nociception assay

(none)

mean latency of tail withdrawal to thermal stimulation (trials 1, 2, 3) [s] mean_TW 34823

BXD

61

both

7-15wks

N=7

2010

Chesler1

nociception assay

(none)

mean latency of nociceptive response to hot plate (transformed) [s] mean_logN_HP 34829

BXD

61

both

7-15wks

N=6

2010

Chesler2

nociception assay

(none)

latency of nociceptive response to pressure on the tail, 60 s test [s] tail_clip 43473

CC diallel w/par

56

both

7-15wks

N=3

2011

Chesler2

nociception assay

(none)

latency of nociceptive response to hot plate (54°C), 30 s test [s] hot_plate 43474

CC diallel w/par

56

both

7-15wks

N=3

2011

Chesler3

nociception assay

(none)

latency of nociceptive response to pressure on the tail, 60 s test [s] tail_clip 43573

CC pre w/par

330

both

7-15wks

N=2

2011

Chesler3

nociception assay

(none)

latency of nociceptive response to hot plate (54°C), 30 s test [s] hot_plate 43574

CC pre w/par

329

both

7-15wks

N=2

2011

Chesler4

nociception assay

(none)

latency of hindpaw withdrawal, 55°C heat stimulation [s] HP_latency 47024

DO population w/par

9

both

12-16wks

N=8

2013

GMC07

nociception assay

(none)

latency of nociceptive response to hot plate [s] latency 55611 reaction1 reaction2

inbred w/CC8

8

both

11-12wks

N=17

2018

GMC07

nociception assay

(none)

type of response to hot plate, first reaction (0=no reaction, 1=shake, 2=lick, 3=jump, 4=other) [designation] response_1 55621

inbred w/CC8

8

both

11-12wks

N=17

2018

GMC07

nociception assay

(none)

type of response to hot plate, second reaction (0=no reaction, 1=shake, 2=lick, 3=jump, 4=other) [designation] response_2 55622

inbred w/CC8

8

both

11-12wks

N=17

2018

Jaxwest1

nociception assay

(none)

hot plate test, latency to respond [s] HP 15123

inbred

7

both

9-12wks

N=8

2003

Jaxwest1

nociception assay

(none)

hot plate test, hindpaw response (0=flick; 1=lick) [score] HP_response 15124

inbred

7

both

9-12wks

N=8

2003

Koide1

nociception assay

(none)

tail flick test: latency to respond [s] TF 1808

wild-derived Mishima

11

f

8-13wks

N=10

2000

Koide1

nociception assay

(none)

hot plate test: latency to respond by licking [s] HP_LICK 1809

wild-derived Mishima

11

f

8-13wks

N=10

2000

Koide1

nociception assay

(none)

hot plate test: latency to respond by jumping [s] HP_JUMP 1810

wild-derived Mishima

11

f

8-13wks

N=10

2000

Koide2

nociception assay

(none)

capsaicin solution consumption, percentage of baseline [%] capsaicin 35802 concentration (µM): 0.5 1 4 7 10 15

wild-derived Mishima

14

both

8-12wks

N=10

2003

Mogil1

nociception assay

(none)

latency of nociceptive response, (53°C) hot plate test [s] HP 2201

inbred

11

m

6-18wks

N=8

2002

Mogil1

nociception assay

(none)

latency of heated hindpaw withdrawal, Hargreaves test [s] HT 2202

inbred

11

m

6-18wks

N=6

2002

Mogil1

nociception assay

(none)

latency of tail withdrawal, 49°C heat stimulation [s] TW_HOT1 2203

inbred

11

m

6-18wks

N=10

2002

Mogil1

nociception assay

(none)

median 50% foot withdrawal threshold, Von Frey test [mN] VF 2204

inbred

11

m

6-18wks

N=7

2002

Mogil1

nociception assay

(none)

number of abdominal constrictions induced with acetic acid (i.p.), 20 min [n] AC_AA 2205

inbred

11

m

6-18wks

N=6

2002

Mogil1

nociception assay

(none)

number of abdominal constrictions induced with magnesium sulfate (i.p.), 5 min [n] AC_MS 2206

inbred

11

m

6-18wks

N=6

2002

Mogil1

nociception assay

(none)

percent hypersensitivity threshold to carrageenan-induced thermal hyperalgesia, treated and heated hindpaw withdrawal [%] CAR_HT 2207

inbred

11

m

6-18wks

N=6

2002

Mogil1

nociception assay

(none)

duration of nociceptive response to acute inflammation (early phase), 0-10 min post-formalin (s.q.) injection [s] F_early 2208

inbred

11

m

6-18wks

N=7

2002

Mogil1

nociception assay

(none)

duration of nociceptive response to subacute/chronic inflammation (late phase), 10-60 min post-formalin (s.q.) injection [s] F_late 2209

inbred

11

m

6-18wks

N=7

2002

Mogil1

nociception assay

(none)

autotomy (neuropathy) score (1-11) following hindlimb denervation [score] AUT 2210

inbred

11

m

6-18wks

N=9

2002

Mogil1

nociception assay

(none)

percent hypersensitivity threshold to Hargreaves test following peripheral nerve injury (PNI) [%] PNI_HT 2211

inbred

11

m

6-18wks

N=6

2002

Mogil1

nociception assay

(none)

median 50% foot withdrawal hypersensitivity threshold to von Frey test following peripheral nerve injury (PNI) [mN] PNI_VF 2212

inbred

11

m

6-18wks

N=7

2002

Mogil1

nociception assay

(none)

duration of nociceptive response to capsaicin [s] CAP 2220

inbred

12

m

6-18wks

N=5

2002

Mogil1

nociception assay

(none)

duration of nociceptive response to bee venom [s] BV 2221

inbred

12

m

6-18wks

N=5

2002

Mogil1

nociception assay

(none)

latency of nociception to heated tail following hindleg acupuncture needles stimulation (analgesia), tail flick test [s] TF 2222

inbred

10

m

6-18wks

N=21

2002

Mogil1

nociception assay

(none)

latency of tail withdrawal, 47°C heat stimulation [s] TW_HOT2 2223

inbred

12

m

6-18wks

N=5

2002

Mogil1

nociception assay

(none)

latency of tail withdrawal, -15°C cold stimulation [s] TW_COLD 2224

inbred

12

m

6-18wks

N=5

2002

Mogil1

nociception assay

(none)

percent hypersensitivity threshold to capsaicin-induced thermal hyperalgesia, tail withdrawal at 47°C [%] CAP_TW 2225

inbred

12

m

6-18wks

N=5

2002

Mogil1

nociception assay

(none)

percent hypersensitivity threshold to bee venom-induced thermal hyperalgesia (ipsilateral), treated and heated hindpaw withdrawal [%] BV_HT 2226

inbred

12

m

6-18wks

N=5

2002

Mogil1

nociception assay

(none)

percent hypersensitivity threshold to bee venom-induced thermal hyperalgesia (contralateral), untreated and heated hindpaw withdrawal [%] BV_HT_CON 2227

inbred

12

m

6-18wks

N=5

2002

Mogil1

nociception assay

(none)

latency of nociception to pinched tail [s] TC 2228

inbred

12

m

6-18wks

N=7

2002

Mogil1

nociception assay

(none)

percent hypersensitivity threshold to mechanical stimulation following dynorphin treatment, von Frey test [%] DYN_VF 2229

inbred

7

m

6-18wks

N=4

2002

Mogil3

nociception assay

(none)

50% hindpaw withdrawal threshold, von Frey test [g] baseline 48001

inbred

18

both

7-12wks

N=3

2012

Mogil3

nociception assay

(none)

percentage of maximum hindpaw mechanical allodynia over 28 days after spared nerve injury [%] allodynia 48002

inbred

18

both

7-12wks

N=3

2012

Recla1

nociception assay

(none)

time to respond to heat [s] latency_to_respond 28501

DO population

both

13-17wks

N=130

2013

Recla2

nociception assay

(none)

wound licking or biting 11-60 min after formalin injection (chronic response) [score] formalin_score 62701

DO population

both

13-17wks

N=138

2018

Recla2

nociception assay

(none)

wound licking or biting 11-60 min after formalin injection (chronic response), square root [sqrt(score)] formalin_score_sqrt 62702

DO population

both

13-17wks

N=138

2018

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