Project measure / variable:   GMC07   response_1

ID, description, units MPD:55621   response_1   type of response to hot plate, first reaction (0=no reaction, 1=shake, 2=lick, 3=jump, 4=other)   [designation]  
Data set, strains GMC07   inbred w/CC8   8 strains     sex: both     age: 11-12wks
Procedure nociception assay
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  STRAIN COMPARISON PLOT
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GMC07 - type of response to hot plate, first reaction (0=no reaction, 1=shake, 2=lick, 3=jump, 4=other)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means1.07   designation 1.01   designation
Median of the strain means1.06   designation 1.00   designation
SD of the strain means± 0.208 ± 0.142
Coefficient of variation (CV)0.195 0.140
Min–max range of strain means0.812   –   1.45   designation 0.812   –   1.29   designation
Mean sample size per strain17.5   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.2182 0.2182 0.715 0.3986
strain 7 7.2814 1.0402 3.408 0.0017
sex:strain 7 0.7356 0.1051 0.3443 0.9329
Residuals 259 79.0521 0.3052


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.812 0.403   16 0.101 0.496 -1.22
129S1/SvImJ m 0.938 0.25   16 0.0625 0.267 -0.52
A/J f 0.812 0.403   16 0.101 0.496 -1.22
A/J m 0.812 0.403   16 0.101 0.496 -1.41
C57BL/6J f 1.06 0.25   16 0.0625 0.235 1.0, 2.0 -0.03
C57BL/6J m 1.12 0.342   16 0.0854 0.304 1.0, 2.0 0.76
CAST/EiJ f 1.16 0.375   19 0.0859 0.324 1.0, 2.0 0.45
CAST/EiJ m 1.0 0.0   17 0.0 0.0 1.0, 1.0 -0.09
NOD/ShiLtJ f 1.06 0.236   18 0.0556 0.223 1.0, 2.0 -0.03
NOD/ShiLtJ m 1.0 0.0   16 0.0 0.0 1.0, 1.0 -0.09
NZO/HlLtJ f 1.18 0.393   17 0.0953 0.334 1.0, 2.0 0.54
NZO/HlLtJ m 1.0 0.0   17 0.0 0.0 1.0, 1.0 -0.09
PWK/PhJ f 1.45 1.1   20 0.246 0.758 1.0, 4.0 1.84
PWK/PhJ m 1.29 1.23   21 0.269 0.957 1.96
WSB/EiJ f 1.0 0.485   18 0.114 0.485 -0.32
WSB/EiJ m 0.938 0.574   16 0.143 0.612 -0.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.8125 0.1381 1.0845 0.5405
129S1/SvImJ m 0.9375 0.1381 1.2095 0.6655
A/J f 0.8125 0.1381 1.0845 0.5405
A/J m 0.8125 0.1381 1.0845 0.5405
C57BL/6J f 1.0625 0.1381 1.3345 0.7905
C57BL/6J m 1.125 0.1381 1.397 0.853
CAST/EiJ f 1.1579 0.1267 1.4075 0.9083
CAST/EiJ m 1.0 0.134 1.2639 0.7361
NOD/ShiLtJ f 1.0556 0.1302 1.312 0.7991
NOD/ShiLtJ m 1.0 0.1381 1.272 0.728
NZO/HlLtJ f 1.1765 0.134 1.4403 0.9126
NZO/HlLtJ m 1.0 0.134 1.2639 0.7361
PWK/PhJ f 1.45 0.1235 1.6933 1.2067
PWK/PhJ m 1.2857 0.1206 1.5231 1.0483
WSB/EiJ f 1.0 0.1302 1.2564 0.7436
WSB/EiJ m 0.9375 0.1381 1.2095 0.6655


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.875 0.0977 1.0673 0.6827
A/J both 0.8125 0.0977 1.0048 0.6202
C57BL/6J both 1.0938 0.0977 1.2861 0.9014
CAST/EiJ both 1.0789 0.0922 1.2605 0.8974
NOD/ShiLtJ both 1.0278 0.0949 1.2147 0.8409
NZO/HlLtJ both 1.0882 0.0947 1.2748 0.9017
PWK/PhJ both 1.3679 0.0863 1.5378 1.1979
WSB/EiJ both 0.9688 0.0949 1.1556 0.7819




  GWAS USING LINEAR MIXED MODELS