Project measure / variable:   Jaxwest1   HP

ID, description, units MPD:15123   HP   hot plate test, latency to respond   [s]  
Data set, strains Jaxwest1   inbred   7 strains     sex: both     age: 9-12wks
Procedure nociception assay
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  STRAIN COMPARISON PLOT
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Jaxwest1 - hot plate test, latency to respond



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means8.64   s 7.42   s
Median of the strain means9.83   s 8.03   s
SD of the strain means± 2.26 ± 2.16
Coefficient of variation (CV)0.261 0.291
Min–max range of strain means5.48   –   11.1   s 4.36   –   10.6   s
Mean sample size per strain8.0   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 42.0175 42.0175 7.7495 0.0064
strain 6 397.7911 66.2985 12.2278 < 0.0001
sex:strain 6 69.7275 11.6213 2.1434 0.0551
Residuals 98 531.3525 5.422


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 9.83 1.96   8 0.693 0.199 7.3, 13.3 0.53
129S1/SvImJ m 8.03 2.11   8 0.744 0.262 5.5, 12.1 0.28
A/J f 9.89 2.34   8 0.827 0.236 6.3, 13.1 0.56
A/J m 8.85 3.23   8 1.14 0.365 5.2, 13.9 0.66
BALB/cJ f 11.1 3.54   8 1.25 0.318 7.6, 19.2 1.09
BALB/cJ m 10.6 3.02   8 1.07 0.287 7.4, 16.8 1.47
C57BL/6J f 5.48 1.99   8 0.703 0.363 3.3, 8.4 -1.4
C57BL/6J m 6.36 1.69   8 0.596 0.265 4.6, 8.9 -0.49
DBA/2J f 5.53 2.72   8 0.961 0.492 2.5, 9.2 -1.38
DBA/2J m 4.36 2.19   8 0.773 0.501 2.3, 8.6 -1.42
NOD/ShiLtJ f 8.64 1.57   8 0.554 0.181 6.6, 11.6 0.0
NOD/ShiLtJ m 8.36 2.43   8 0.86 0.291 6.2, 13.5 0.43
SJL/J f 9.99 1.42   8 0.501 0.142 8.0, 12.0 0.6
SJL/J m 5.4 0.854   8 0.302 0.158 4.1, 6.9 -0.94


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 9.825 0.8233 11.4587 8.1913
129S1/SvImJ m 8.025 0.8233 9.6587 6.3913
A/J f 9.8875 0.8233 11.5212 8.2538
A/J m 8.85 0.8233 10.4837 7.2163
BALB/cJ f 11.15 0.8233 12.7837 9.5163
BALB/cJ m 10.55 0.8233 12.1837 8.9163
C57BL/6J f 5.475 0.8233 7.1087 3.8413
C57BL/6J m 6.3625 0.8233 7.9962 4.7288
DBA/2J f 5.525 0.8233 7.1587 3.8913
DBA/2J m 4.3625 0.8233 5.9962 2.7288
NOD/ShiLtJ f 8.6375 0.8233 10.2712 7.0038
NOD/ShiLtJ m 8.3625 0.8233 9.9962 6.7288
SJL/J f 9.9875 0.8233 11.6212 8.3538
SJL/J m 5.4 0.8233 7.0337 3.7663


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8.925 0.5821 10.0802 7.7698
A/J both 9.3687 0.5821 10.524 8.2135
BALB/cJ both 10.85 0.5821 12.0052 9.6948
C57BL/6J both 5.9188 0.5821 7.074 4.7635
DBA/2J both 4.9438 0.5821 6.099 3.7885
NOD/ShiLtJ both 8.5 0.5821 9.6552 7.3448
SJL/J both 7.6937 0.5821 8.849 6.5385




  GWAS USING LINEAR MIXED MODELS