MPD: Phenotype measures mapped to MP:0020158, abnormal behavioral response to cocaine

Phenotype measures associated with ontology term
MP:0020158 'abnormal behavioral response to cocaine'

This MP term has been mapped to these MPD phenotype measurements to help users find relevant data. It should be noted that MPD measurements typically have a mixture of high-end, low-end and "normal" readings.

Sort/ Pick	Data set	Procedure / Protocol	Drug or Challenge	Phenotype Measure / Variable	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Dickson2:31	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, mean number of infusions (fixed ratio 1 (FR1) schedule), over ten 120 min sessions [n] FR1_infusions_mean 54831 measure	DO population		both	12-16wks	N=35	2015

Dickson2:32	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, mean number of responses on the active lever (fixed ratio 1 (FR1) schedule), over ten 120 min sessions [n] FR1_active_mean 54832 measure	DO population		both	12-16wks	N=35	2015

Dickson2:33	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, mean number of responses on the inactive lever (fixed ratio 1 (FR1) schedule), over ten 120 min sessions [n] FR1_inactive_mean 54833 measure	DO population		both	12-16wks	N=35	2015

Dickson2:41	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, breakpoint for infusions (progressive ratio (PR) schedule), one 6h test [n] PR_infusions_breakpoint 54841 measure	DO population		both	12-16wks	N=31	2015

Dickson2:42	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, number of presses on the active lever (progressive ratio (PR) schedule), one 6h test [n] PR_active 54842 measure	DO population		both	12-16wks	N=31	2015

Dickson2:43	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, number of presses on the inactive lever (progressive ratio (PR) schedule), one 6h test [n] PR_inactive 54843 measure	DO population		both	12-16wks	N=31	2015

Jentsch2:1	Jentsch2	operant conditioning chamber	cocaine	number of sessions (days) required to reach criteria for self-administration (FR1 reinforcement schedule) [d] acquisition_FR1 49701 measure	BXD	4	both	8-17wks	N=8	2013

Jentsch2:2	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 1 - self administration: number of infusions earned [n] infusions_FR1 49702 measure day 1 day 3 day 5 last day	BXD	4	both	8-17wks	N=8	2013

Jentsch2:6	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 1 - discrimination index between active and inactive levers [%] discrimination_FR1 49706 measure day 1 day 3 day 5 last day	BXD	4	both	8-17wks	N=7	2013

Jentsch2:10	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 1 - time-out: number of responses [n] timeout_FR1 49710 measure day 1 day 3 day 5 last day	BXD	4	both	8-17wks	N=7	2013

Jentsch2:14	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 2 - self administration: number of infusions earned [n] infusions_FR2 49714 measure day 1 day 2 day 4	BXD	4	both	8-17wks	N=6	2013

Jentsch2:17	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 2 - discrimination index between active and inactive levers [%] discrimination_FR2 49717 measure day 1 day 2 day 4	BXD	4	both	8-17wks	N=6	2013

Jentsch2:20	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 2 - time-out: number of responses [n] timeout_FR2 49720 measure day 1 day 2 day 4	BXD	4	both	8-17wks	N=6	2013

Jentsch2:23	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 5 - self administration: number of infusions earned [n] infusions_FR5 49723 measure day 1 day 3 day 5	BXD	4	both	8-17wks	N=6	2013

Jentsch2:26	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 5 - discrimination index between active and inactive levers [%] discrimination_FR5 49726 measure day 1 day 3 day 5	BXD	4	both	8-17wks	N=6	2013

Jentsch2:29	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 5 - time-out: number of responses [n] timeout_FR5 49729 measure day 1 day 3 day 5	BXD	4	both	8-17wks	N=6	2013

Jentsch2:32	Jentsch2	operant conditioning chamber	cocaine	horizontal beam breaks [n] activity 49732 measure baseline 5 mg/kg 10 mg/kg 20 mg/kg	BXD	4	f	8-17wks	N=13	2013

Kumar1:1	Kumar1	circadian wheel running	cocaine	cocaine response over 30 minutes; data are averaged in 5 minute bins and then summed over 30 minutes [cm x 100] 1sum_5min_avg 29001 measure	QTL population		both	10-14wks	N=122	2014

Kumar1:2	Kumar1	circadian wheel running	cocaine	cocaine response over 60 minutes; data are averaged in 5 minute bins and then summed over 60 minutes [cm x 100] 1sum_60min 29002 measure	QTL population		both	10-14wks	N=122	2014

Kumar1:4	Kumar1	circadian wheel running	cocaine	average speed over 30 minutes after cocaine response [cm x 100 / min] 130avg 29004 measure	QTL population		both	10-14wks	N=122	2014

Kumar1:5	Kumar1	circadian wheel running	cocaine	net response–baselineavg subtracted from 30avg [cm x 100 / min] 1resp-baseline 29005 measure	QTL population		both	10-14wks	N=122	2014

Tarantino1:11	Tarantino1	open field test	cocaine	distance traveled, 30 min test [cm] dist 45911 measure baseline treated difference	inbred	45	m	8-11wks	N=18	2015

Tarantino1:16	Tarantino1	open field test	cocaine	ambulatory episodes, 30 min test [n] amb_epi 45916 measure baseline treated difference	inbred	45	m	8-11wks	N=18	2015

Tarantino1:21	Tarantino1	open field test	cocaine	rearing episodes, 30 min test [n] rear 45921 measure baseline treated difference	inbred	45	m	8-11wks	N=18	2015

Tarantino1:26	Tarantino1	open field test	cocaine	average velocity, 30 min test [cm/s] vel 45926 measure baseline treated difference	inbred	45	m	8-11wks	N=18	2015

Tarantino1:31	Tarantino1	open field test	cocaine	percentage of time resting, 30 min test [%] rest 45931 measure baseline treated difference	inbred	45	m	8-11wks	N=18	2015

Thomsen1:1	Thomsen1	open field test	cocaine	total activity, test 1, 3h test [n] activ_cocaine1 40701 measure baseline dose mg/kg i.p.: 3 10 18 32 56	inbred	15	both	8-10wks	N=8	2011

Thomsen1:7	Thomsen1	open field test	cocaine	total activity, test 2, 3h test [n] activ_cocaine2 40707 measure baseline dose mg/kg i.p.: 3 10 32	inbred	15	both	8-10wks	N=8	2011

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