MPD: Phenotype measures mapped to MP:0020158, abnormal behavioral response to cocaine

Phenotype measures associated with ontology term
MP:0020158 'abnormal behavioral response to cocaine'

This MP term has been mapped to these MPD phenotype measurements to help users find relevant data. It should be noted that MPD measurements typically have a mixture of high-end, low-end and "normal" readings.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Dickson2:31	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, mean number of infusions (fixed ratio 1 (FR1) schedule), over ten 120 min sessions [n] FR1_infusions_mean 54831	DO population		both	12-16wks	N=35	2015

Dickson2:32	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, mean number of responses on the active lever (fixed ratio 1 (FR1) schedule), over ten 120 min sessions [n] FR1_active_mean 54832	DO population		both	12-16wks	N=35	2015

Dickson2:33	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, mean number of responses on the inactive lever (fixed ratio 1 (FR1) schedule), over ten 120 min sessions [n] FR1_inactive_mean 54833	DO population		both	12-16wks	N=35	2015

Dickson2:41	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, breakpoint for infusions (progressive ratio (PR) schedule), one 6h test [n] PR_infusions_breakpoint 54841	DO population		both	12-16wks	N=31	2015

Dickson2:42	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, number of presses on the active lever (progressive ratio (PR) schedule), one 6h test [n] PR_active 54842	DO population		both	12-16wks	N=31	2015

Dickson2:43	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, number of presses on the inactive lever (progressive ratio (PR) schedule), one 6h test [n] PR_inactive 54843	DO population		both	12-16wks	N=31	2015

Jentsch2:1	Jentsch2	operant conditioning chamber	cocaine	number of sessions (days) required to reach criteria for self-administration (FR1 reinforcement schedule) [d] acquisition_FR1 49701	BXD	4	both	8-17wks	N=8	2013

Jentsch2:2	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 1 - self administration: number of infusions earned [n] infusions_FR1 49702 day 1 day 3 day 5 last day	BXD	4	both	8-17wks	N=8	2013

Jentsch2:6	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 1 - discrimination index between active and inactive levers [%] discrimination_FR1 49706 day 1 day 3 day 5 last day	BXD	4	both	8-17wks	N=7	2013

Jentsch2:10	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 1 - time-out: number of responses [n] timeout_FR1 49710 day 1 day 3 day 5 last day	BXD	4	both	8-17wks	N=7	2013

Jentsch2:14	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 2 - self administration: number of infusions earned [n] infusions_FR2 49714 day 1 day 2 day 4	BXD	4	both	8-17wks	N=6	2013

Jentsch2:17	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 2 - discrimination index between active and inactive levers [%] discrimination_FR2 49717 day 1 day 2 day 4	BXD	4	both	8-17wks	N=6	2013

Jentsch2:20	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 2 - time-out: number of responses [n] timeout_FR2 49720 day 1 day 2 day 4	BXD	4	both	8-17wks	N=6	2013

Jentsch2:23	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 5 - self administration: number of infusions earned [n] infusions_FR5 49723 day 1 day 3 day 5	BXD	4	both	8-17wks	N=6	2013

Jentsch2:26	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 5 - discrimination index between active and inactive levers [%] discrimination_FR5 49726 day 1 day 3 day 5	BXD	4	both	8-17wks	N=6	2013

Jentsch2:29	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 5 - time-out: number of responses [n] timeout_FR5 49729 day 1 day 3 day 5	BXD	4	both	8-17wks	N=6	2013

Jentsch2:32	Jentsch2	operant conditioning chamber	cocaine	horizontal beam breaks [n] activity 49732 baseline 5 mg/kg 10 mg/kg 20 mg/kg	BXD	4	f	8-17wks	N=13	2013

Kumar1:1	Kumar1	circadian wheel running	cocaine	cocaine response over 30 minutes; data are averaged in 5 minute bins and then summed over 30 minutes [cm x 100] 1sum_5min_avg 29001	QTL population		both	10-14wks	N=122	2014

Kumar1:2	Kumar1	circadian wheel running	cocaine	cocaine response over 60 minutes; data are averaged in 5 minute bins and then summed over 60 minutes [cm x 100] 1sum_60min 29002	QTL population		both	10-14wks	N=122	2014

Kumar1:4	Kumar1	circadian wheel running	cocaine	average speed over 30 minutes after cocaine response [cm x 100 / min] 130avg 29004	QTL population		both	10-14wks	N=122	2014

Kumar1:5	Kumar1	circadian wheel running	cocaine	net response–baselineavg subtracted from 30avg [cm x 100 / min] 1resp-baseline 29005	QTL population		both	10-14wks	N=122	2014

Tarantino1:2	Tarantino1	open field test	cocaine	distance traveled, 30 min test [cm] dist 45911 baseline (day 2) treated (day 3) difference	inbred	45	m	8-11wks	N=18	2015

Tarantino1:5	Tarantino1	open field test	cocaine	ambulatory episodes, 30 min test [n] amb_epi 45916 baseline (day 2) treated (day 3) difference	inbred	45	m	8-11wks	N=18	2015

Tarantino1:8	Tarantino1	open field test	cocaine	rearing episodes, 30 min test [n] rear 45921 baseline (day 2) treated (day 3) difference	inbred	45	m	8-11wks	N=18	2015

Tarantino1:11	Tarantino1	open field test	cocaine	average velocity, 30 min test [cm/s] vel 45926 baseline (day 2) treated (day 3) difference	inbred	45	m	8-11wks	N=18	2015

Tarantino1:14	Tarantino1	open field test	cocaine	percentage of time resting, 30 min test [%] rest 45931 baseline (day 2) treated (day 3) difference	inbred	45	m	8-11wks	N=18	2015

Thomsen1:1	Thomsen1	open field test	cocaine	total activity, test 1, 3h test [n] activ_cocaine1 40701 baseline dose mg/kg i.p.: 3 10 18 32 56	inbred	15	both	8-10wks	N=8	2011

Thomsen1:7	Thomsen1	open field test	cocaine	total activity, test 2, 3h test [n] activ_cocaine2 40707 baseline dose mg/kg i.p.: 3 10 32	inbred	15	both	8-10wks	N=8	2011

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