MPD: Phenotype measures mapped to MP:0008875, abnormal xenobiotic pharmacokinetics

Phenotype measures associated with ontology term
MP:0008875 'abnormal xenobiotic pharmacokinetics'

This list also includes ontology descendants of MP:0008875. Or, you can show MP:0008875 only.

MP:0008875 abnormal xenobiotic pharmacokinetics
MP:0012691 abnormal acetaminophen metabolism
MP:0012692 abnormal fluoxetine metabolism
MP:0012696 abnormal trichloroethene metabolism

This MP term has been mapped to these MPD phenotype measurements to help users find relevant data. It should be noted that MPD measurements typically have a mixture of high-end, low-end and "normal" readings.

Sort/ Pick	Data set	Procedure / Protocol	Drug or Challenge	Phenotype Measure	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Crabbe2:1	Crabbe2	drug and metabolite quantification	diazepam	brain diazepam and metabolite concentration, 30 min post-injection [ng/g] brain_DZ 15501 8 mg/kg 16 mg/kg	inbred	15	m	6-7wks	N=8	1998

Crabbe2:3	Crabbe2	drug and metabolite quantification	diazepam	brain diazepam and metabolite concentration, <5 min post-injection, after rotarod [ng/g] brain_DZ20 15503 trial block1 trial block2	inbred	8	m	6-7wks	N=13	1998

Crowley1:3	Crowley1	drug and metabolite quantification	haloperidol	plasma haloperidol concentration [nM] haloperidol 39403 day: 30 60 90 120	inbred w/CC8	27	m	9-28wks	N=6	2012

Harrill2:55	Harrill2	drug and metabolite quantification	DB289	kidney metabolite (DB75) concentration [µM] kidney_DB75 44155 control DB289	inbred	23	f	6-8wks	N=4	2012

Rusyn2:67	Rusyn2	drug and metabolite quantification	trichloroethylene	dichloroacetic acid (serum DCA x 10^-3) [nmol/mL] DCA_tce 36167 time after treatment: 2h 8h 24h	inbred	15	m	7wks	N=3	2010

Rusyn2:75	Rusyn2	drug and metabolite quantification	trichloroethylene	trichloroacetic acid (serum TCA) [nmol/mL] TCA_tce 36175 time after treatment: 2h 8h 24h	inbred	15	m	7wks	N=3	2010

Rusyn6:2	Rusyn6	drug and metabolite quantification	trichloroethylene	trichloroacetic acid (serum TCA) [nmol/mL] TCA_serum_tce 51202	inbred	7	m	6-7wks	N=3	2014

Rusyn6:4	Rusyn6	drug and metabolite quantification	trichloroethylene	dichloroacetic acid (serum DCA) [nmol/mL] DCA_serum_tce 51204	inbred	7	m	6-7wks	N=3	2014

Rusyn6:6	Rusyn6	drug and metabolite quantification	trichloroethylene	S-(1,2-dichlorovinyl) glutathione (serum DCVG) [pmol/mL] DCVG_serum_tce 51206	inbred	4	m	6-7wks	N=2	2014

Rusyn6:8	Rusyn6	drug and metabolite quantification	trichloroethylene	S-(1,2-dichlorovinyl)-L-cysteine (serum DCVC) [pmol/mL] DCVC_serum_tce 51208	inbred	7	m	6-7wks	N=3	2014

Rusyn6:16	Rusyn6	drug and metabolite quantification	trichloroethylene	trichloroacetic acid (liver TCA) [nmol/g] TCA_liver_tce 51216	inbred	7	m	6-7wks	N=4	2014

Rusyn6:18	Rusyn6	drug and metabolite quantification	trichloroethylene	dichloroacetic acid (liver DCA) [nmol/g] DCA_liver_tce 51218	inbred	7	m	6-7wks	N=4	2014

Rusyn6:20	Rusyn6	drug and metabolite quantification	trichloroethylene	trichloroethanol (liver TCOH) [nmol/g] TCOH_liver_tce 51220	inbred	7	m	6-7wks	N=4	2014

Rusyn6:22	Rusyn6	drug and metabolite quantification	trichloroethylene	S-(1,2-dichlorovinyl) glutathione (liver DCVG) [pmol/g] DCVG_liver_tce 51222	inbred	7	m	6-7wks	N=4	2014

Rusyn6:58	Rusyn6	drug and metabolite quantification	trichloroethylene	trichloroacetic acid (kidney TCA) [nmol/g] TCA_kidney_tce 51258	inbred	7	m	6-7wks	N=4	2014

Rusyn6:60	Rusyn6	drug and metabolite quantification	trichloroethylene	dichloroacetic acid (kidney DCA) [nmol/g] DCA_kidney_tce 51260	inbred	6	m	6-7wks	N=3	2014

Rusyn6:62	Rusyn6	drug and metabolite quantification	trichloroethylene	trichloroethanol (kidney TCOH) [nmol/g] TCOH_kidney_tce 51262	inbred	7	m	6-7wks	N=4	2014

Rusyn6:64	Rusyn6	drug and metabolite quantification	trichloroethylene	S-(1,2-dichlorovinyl) glutathione (kidney DCVG) [pmol/g] DCVG_kidney_tce 51264	inbred	6	m	6-7wks	N=2	2014

Rusyn6:66	Rusyn6	drug and metabolite quantification	trichloroethylene	S-(1,2-dichlorovinyl)-L-cysteine (kidney DCVC) [pmol/g] DCVC_kidney_tce 51266	inbred	6	m	6-7wks	N=2	2014

Threadgill2:9	Threadgill2	drug and metabolite quantification	acetaminophen	serum acetaminophen (APAP), 50 mg/mL dose acetaminophen [µg/mL] APAP50 39609 baseline 0.5h 1h 2h 3h 6h	inbred	5	m	6-8wks	N=5	2005

Threadgill2:16	Threadgill2	drug and metabolite quantification	acetaminophen	serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen [µg/mL] APAP_Sulf_50 39616 baseline 0.5h 1h 2h 3h 6h	inbred	5	m	6-8wks	N=5	2005

Threadgill2:22	Threadgill2	drug and metabolite quantification	acetaminophen	serum acetaminophen glucuronide (APAP-Glc), 50 mg/mL dose acetaminophen [µg/mL] APAP_Glc_50 39622 baseline 0.5h 1h 2h 3h 6h	inbred	5	m	6-8wks	N=4	2005

Threadgill2:32	Threadgill2	drug and metabolite quantification	acetaminophen	serum acetaminophen (APAP), 300 mg/mL dose acetaminophen [µg/mL] APAP300 39632 baseline 0.5h 1h 2h 3h 6h	inbred	5	m	6-8wks	N=5	2005

Threadgill2:38	Threadgill2	drug and metabolite quantification	acetaminophen	serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen [µg/mL] APAP_Sulf_300 39638 baseline 0.5h 1h 2h 3h 6h	inbred	5	m	6-8wks	N=5	2005

Threadgill2:39	Threadgill2	drug and metabolite quantification	acetaminophen	serum acetaminophen glucuronide (APAP-Glc), 300 mg/mL dose acetaminophen [µg/mL] APAP_Glc_300 39639 baseline 0.5h 1h 2h 3h 6h	inbred	5	m	6-8wks	N=5	2005

Wiltshire2:7	Wiltshire2	drug and metabolite quantification	fluoxetine	drug and metabolite concentration [ng/mL] fluoxetine 38007 fluoxetine norfluoxetine	inbred	30	m	10-11wks	N=11	2011

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