Project measure / variable:   Rusyn6   TCA_liver_tce

ID, description, units MPD:51216   TCA_liver_tce   trichloroacetic acid (liver TCA)   [nmol/g]  
trichloroethylene study
Data set, strains Rusyn6   inbred   7 strains     sex: m     age: 6-7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn6 - trichloroacetic acid (liver TCA)



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means1322   nmol/g
Median of the strain means1498   nmol/g
SD of the strain means± 442
Coefficient of variation (CV)0.334
Min–max range of strain means495   –   1771   nmol/g
Mean sample size per strain3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 3945276.1571 657546.0262 7.2923 0.0004
Residuals 19 1713217.4783 90169.341


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 1057.0 45.0   4 22.5 0.0426 1005.0, 1114.0 -0.6
A/J m 1695.0 590.0   4 295.0 0.348 1104.0, 2407.0 0.84
BTBR T+ Itpr3tf/J m 1511.0 135.0   3 77.8 0.0891 1374.0, 1644.0 0.43
C57BL/6J m 1498.0 345.0   4 173.0 0.23 1202.0, 1894.0 0.4
CAST/EiJ m 495.0 12.3   3 7.09 0.0248 481.0, 504.0 -1.87
NOD/ShiLtJ m 1230.0 192.0   4 96.0 0.156 1098.0, 1505.0 -0.21
NZW/LacJ m 1771.0 230.0   4 115.0 0.13 1469.0, 1988.0 1.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 1057.0 150.1411 1371.2488 742.7512
A/J m 1695.175 150.1411 2009.4238 1380.9262
BTBR T+ Itpr3tf/J m 1511.0667 173.368 1873.93 1148.2034
C57BL/6J m 1498.325 150.1411 1812.5738 1184.0762
CAST/EiJ m 494.8667 173.368 857.73 132.0034
NOD/ShiLtJ m 1229.95 150.1411 1544.1988 915.7012
NZW/LacJ m 1770.8 150.1411 2085.0488 1456.5512




  GWAS USING LINEAR MIXED MODELS